Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
4.9%

Vaynevs Galio

BMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 6, 2026
MethodologyData Methodology

Vayne vs Galio is a decisive matchup in LoL patch 26.11. Galio wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Galio wins the early laning phase while Vayne scales better into the late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Galio matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 40.0% win rate in this matchup
Vayne
40.0% WR
VS
Galio vs Vayne matchup - 60.0% win rate
Galio
60.0% WR

Who Wins the Vayne vs Galio Matchup?

Galio wins the Vayne vs Galio matchup
Winner
Galio
Matches: 5
40.0%
Win Rate
60.0%
6.4
CS / min
5.9
726
DMG / min
613
9,892
Gold / game
9,436
205
Heal / min
110
372
DMG Mitigated / min
1,047
0.4
CC / min
1.2
40.0%
Early Game WR
60.0%
0.0%
Late Game WR
0.0%

Vayne vs Galio Matchup Summary

The Vayne vs Galio matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Galio wins with a 60.0% win rate compared to Vayne's 40.0%, giving Galio a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Galio controls the early laning stage, but Vayne outscales as the game goes longer. The matchup shifts dramatically depending on game length — Galio needs to press advantages before Vayne reaches their power spikes, while Vayne should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Galio leads by 0.8s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Galio has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Galio overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Galio Laning Phase Breakdown

Vayne wins the laning phase against Galio in League of Legends

Vayne is favored during the laning phase against Galio, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.4Vayne
5.9Galio
Vayne edges out Galio by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 8 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
726Vayne
613Galio
Vayne heavily out-damages Galio by 113 DMG/min, dominating both short trades and all-in fights. Galio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
9,892Vayne
9,436Galio
Vayne earns 456 more gold per game than Galio, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.4Vayne
1.2Galio
Galio provides 0.8 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Galio coordinate with their jungler and control the pace of skirmishes.
Sustain
578Vayne
1,157Galio
Galio vastly out-sustains Vayne, healing and mitigating 580 more damage per minute. This massive durability gap means Galio can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Galio
60.0%
+20.0% advantage
Vayne early game win rateVayne40.0%
Galio early game win rateGalio60.0%
Late Game
Vayne
0.0%
+0.0% advantage
Vayne late game win rateVayne0.0%
Galio late game win rateGalio0.0%

Galio dominates the early game (first 15 minutes) with a commanding 60.0% win rate — a 20.0 percentage point lead over Vayne. This lopsided early game means Galio can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Vayne at 0.0% win rate — only 0.0 points ahead of Galio. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Galio has the edge early, but Vayne gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Vayne Runes Against Galio

Precision rune tree - Vayne primary runes vs GalioPrecision
Press the Attack - best Vayne rune vs GalioTriumph - best Vayne rune vs GalioLegend: Alacrity - best Vayne rune vs GalioCoup de Grace - best Vayne rune vs Galio
Domination rune tree - Vayne secondary runes vs GalioDomination
Taste of Blood - best Vayne rune vs GalioTreasure Hunter - best Vayne rune vs Galio
100.0% WR

The Precision and Domination rune setup gives Vayne the best tools to compete against Galio in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Galio - Frequently Asked Questions

How does Vayne do against Galio in League of Legends?

Galio wins the Vayne vs Galio matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.11.

How does Vayne do against Galio in the early game?

In the early game, Galio has the advantage against Vayne with a 60.0% win rate versus 40.0%. Galio players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Galio in the late game?

In the late game, Vayne takes over the Vayne vs Galio matchup with a 0.0% win rate compared to 0.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Galio matchup?

Galio wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.11. The 20.0 percentage point advantage means Galio is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Galio?

The best Vayne build against Galio includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Galio?

The best Vayne runes against Galio use the Precision primary tree with Domination secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Galio matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Galio?

No, Vayne struggles against Galio with only a 40.0% win rate. Galio has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Galio's lead.

How do I play Vayne against Galio?

When playing Vayne against Galio, play cautiously and avoid Galio's power spikes. Focus on safe farming — you outscale Galio in the late game. Use the matchup-specific build and runes above to optimize your chances.