Vayne - League of Legends Champion
Win Rate
50.1%
Pick Rate
4.8%

Vaynevs Galio

CMarksmanAssassin
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Vayne vs Galio is a decisive matchup in LoL patch 26.14. Galio wins with a 100.0% win rate (+100.0%) over Vayne based on 5 games. Galio holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Galio matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 0.0% win rate in this matchup
Vayne
0.0% WR
VS
Galio vs Vayne matchup - 100.0% win rate
Galio
100.0% WR

Who Wins the Vayne vs Galio Matchup?

Galio wins the Vayne vs Galio matchup
Winner
Galio
Matches: 5
0.0%
Win Rate
100.0%
5.7
CS / min
5.4
822
DMG / min
508
10,600
Gold / game
10,355
246
Heal / min
104
609
DMG Mitigated / min
943
0.3
CC / min
1.0
0.0%
Early Game WR
100.0%
0.0%
Late Game WR
100.0%

Vayne vs Galio Matchup Summary

The Vayne vs Galio matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Galio wins with a 100.0% win rate compared to Vayne's 0.0%, giving Galio a 100.0 percentage point advantage. Galio dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Galio leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Galio has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Galio overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Galio Laning Phase Breakdown

Vayne wins the laning phase against Galio in League of Legends

Vayne is favored during the laning phase against Galio, winning 3 out of 5 key stat categories. Vayne holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
5.7Vayne
5.4Galio
Vayne and Galio farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
822Vayne
508Galio
Vayne heavily out-damages Galio by 314 DMG/min, dominating both short trades and all-in fights. Galio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
10,600Vayne
10,355Galio
Vayne and Galio generate nearly equal gold per game, with just a 245 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.3Vayne
1.0Galio
Galio provides 0.7 seconds more crowd control per minute than Vayne, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Galio coordinate with their jungler and control the pace of skirmishes.
Sustain
855Vayne
1,048Galio
Galio vastly out-sustains Vayne, healing and mitigating 192 more damage per minute. This massive durability gap means Galio can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Galio

Berserker's Greaves is the optimal boots choice against Galio, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Galio are Maw of Malmortius, Blade of The Ruined King and Randuin's Omen. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Galio matchup.

Early Game vs Late Game

Early Game
Galio
100.0%
+100.0% advantage
Vayne early game win rateVayne0.0%
Galio early game win rateGalio100.0%
Late Game
Galio
100.0%
+100.0% advantage
Vayne late game win rateVayne0.0%
Galio late game win rateGalio100.0%

Galio dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Galio can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Galio is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Vayne. Extended games heavily favor Galio, whose kit and scaling make them a dominant force in team fights and objective control.

Galio holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Galio

Precision rune tree - Vayne primary runes vs GalioPrecision
Lethal Tempo - best Vayne rune vs GalioTriumph - best Vayne rune vs GalioLegend: Alacrity - best Vayne rune vs GalioCoup de Grace - best Vayne rune vs Galio
Resolve rune tree - Vayne secondary runes vs GalioResolve
Conditioning - best Vayne rune vs GalioOvergrowth - best Vayne rune vs Galio
0.0% WR

The Precision and Resolve rune setup gives Vayne the best tools to compete against Galio in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.14. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
48.56%3485.884712,97944.1%50.9%
53.42%3075.983912,94048.8%56.6%
48.20%2786.183613,47041.3%51.6%
47.74%2436.286012,61047.6%47.9%
53.08%2116.387812,62143.0%61.0%
41.53%1836.177312,60338.8%43.1%
52.78%1446.179112,82955.8%51.1%
51.91%1316.488114,08340.9%57.5%
41.41%1286.189212,80238.3%43.2%
49.00%1006.395213,52845.7%50.8%
42.86%986.082513,13140.0%44.1%
52.75%916.289012,27555.1%50.0%
50.00%885.772712,17443.8%53.6%
51.81%836.191011,36254.5%50.0%
47.50%806.182012,47545.7%48.9%
60.00%656.097412,77468.2%55.8%
50.00%646.084711,77746.1%52.6%
62.50%646.189912,62366.7%58.8%
33.33%605.769810,50028.6%37.5%
64.91%576.11,04212,26760.0%68.8%
50.88%576.178712,25354.8%46.1%
53.57%565.872512,48543.5%60.6%
47.17%536.472112,52633.3%58.6%
45.28%535.774511,42548.1%42.3%
40.38%526.080712,80542.9%38.7%
52.00%505.675710,82771.4%37.9%
24.00%505.559310,36710.5%32.3%
50.00%486.380412,29937.5%62.5%
43.48%465.983113,24640.0%46.1%
64.44%456.61,35613,35552.9%71.4%
44.19%436.578312,29642.9%45.5%
48.78%416.287913,46428.6%59.3%
52.94%346.789613,04850.0%55.6%
63.64%336.51,11612,11253.3%72.2%
62.50%326.381912,63145.5%71.4%
59.38%326.185412,12688.9%47.8%
38.71%315.71,02511,46427.3%45.0%
54.84%315.882011,57820.0%71.4%
67.74%316.01,05512,46354.5%75.0%
43.33%306.287912,49536.4%47.4%
53.33%306.51,29614,35044.4%57.1%
42.86%285.983212,55236.4%47.1%
66.67%276.389310,71269.2%64.3%
62.96%276.31,01010,80457.1%69.2%
51.85%276.682711,71960.0%47.1%
40.00%255.91,07612,66655.6%31.3%
66.67%246.385111,36875.0%58.3%
41.67%246.598211,95853.9%27.3%
39.13%235.380811,11011.1%57.1%
43.48%235.990312,03940.0%44.4%
52.17%236.371612,15850.0%53.3%
50.00%226.378612,37350.0%50.0%
50.00%226.387711,26933.3%61.5%
54.55%226.194413,47650.0%56.3%
50.00%225.785710,86766.7%38.5%
61.90%215.780711,32255.6%66.7%
38.10%216.188512,47866.7%26.7%
47.62%216.379414,04633.3%50.0%
40.00%206.189612,75940.0%40.0%
68.42%196.195110,33575.0%63.6%
57.89%196.381312,24550.0%63.6%
50.00%185.893811,87355.6%44.4%
70.59%176.41,04113,11580.0%66.7%
56.25%166.581114,11950.0%58.3%
43.75%165.673311,69628.6%55.6%
31.25%166.073811,87840.0%27.3%
62.50%166.294612,97250.0%70.0%
46.67%156.06619,61655.6%33.3%
66.67%156.293814,61825.0%81.8%
78.57%146.891815,770100.0%70.0%
35.71%146.29069,94233.3%37.5%
71.43%146.484613,11242.9%100.0%
64.29%146.11,14912,06157.1%71.4%
53.85%135.981013,10933.3%60.0%
53.85%135.41,01713,23150.0%57.1%
53.85%135.875710,86575.0%20.0%
50.00%126.389413,15325.0%62.5%
58.33%126.586310,15833.3%83.3%
41.67%124.489010,67950.0%25.0%
54.55%115.776412,34433.3%62.5%
50.00%106.483812,06366.7%42.9%
80.00%106.084712,029100.0%66.7%
33.33%95.072312,6860.0%50.0%
22.22%94.078213,4440.0%33.3%
66.67%94.388214,962100.0%62.5%
77.78%95.579215,017100.0%71.4%
25.00%86.486611,04250.0%0.0%
37.50%84.578011,84250.0%33.3%
12.50%84.482311,95525.0%0.0%
71.43%76.479513,70250.0%80.0%
42.86%74.852210,75633.3%50.0%
33.33%66.082514,1640.0%40.0%
50.00%63.246210,33966.7%33.3%
16.67%65.193311,15633.3%0.0%
50.00%64.07398,97350.0%50.0%
50.00%63.16307,38350.0%50.0%
83.33%65.571814,890100.0%80.0%
66.67%65.997916,5040.0%66.7%
16.67%64.784611,2830.0%25.0%
40.00%50.751211,18333.3%50.0%
0.00%55.782210,6000.0%0.0%
60.00%56.979212,10050.0%66.7%
60.00%54.298815,3860.0%60.0%
40.00%54.57149,28266.7%0.0%

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Vayne vs Galio - Frequently Asked Questions

How does Vayne do against Galio in League of Legends?

Galio wins the Vayne vs Galio matchup with a 100.0% win rate compared to Vayne's 0.0%, a 100.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.14.

How does Vayne do against Galio in the early game?

In the early game, Galio has the advantage against Vayne with a 100.0% win rate versus 0.0%. Galio players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Galio in the late game?

In the late game, Galio takes over the Vayne vs Galio matchup with a 100.0% win rate compared to 0.0%. Galio scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Galio matchup?

Galio wins the matchup against Vayne with a 100.0% win rate in League of Legends patch 26.14. The 100.0 percentage point advantage means Galio is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Vayne build against Galio?

The best Vayne build against Galio includes Maw of Malmortius, Blade of The Ruined King, Randuin's Omen with Berserker's Greaves. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Galio?

The best Vayne runes against Galio use the Precision primary tree with Resolve secondary. This rune setup achieves a 0.0% win rate in the Vayne vs Galio matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Galio?

No, Vayne struggles against Galio with only a 0.0% win rate. Galio has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Galio's lead.

How do I play Vayne against Galio?

When playing Vayne against Galio, play cautiously and avoid Galio's power spikes. Look for jungle assistance and team-dependent plays since Galio has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.