Strike•Attack

Is Strike good in Slay the Spire 2?

Strike is a basic Regent attack in Slay the Spire 2. In combat it resolves as: Deal 6 damage. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 165 recorded runs, decks running it win 10.6% of the time, trailing the 12.6% average by 2.1%. It’s a popular draft, appearing in 31.8% of eligible decks. Regent players keep it in 99.4% of their runs, so it’s a familiar sight in those decks. On average it shows up 3.8 times in the decks that take it.

It performs best next to Mad Science — together they post a +89.4% swing in win rate. It also has strong chemistry with the relic Ornamental Fan, which moves its win rate by +89.4%. At 1 energy, it’s upgraded in 3.1% of runs and usually joins the deck around floor 1.

Upgraded, it gains +3 Damage, which is why so many decks invest a rest-site upgrade in it. That’s 15 wins, 127 deaths, and 23 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Terror Eel Elite, which closes out 7.3% of its appearances. Read on for Strike’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Strike

Ranked by win-rate lift, Strike performs best alongside Mad Science (+89.4%), Mayhem (+64.4%), and Stratagem (+56.1%).

Mad Science+89.4%5 runsMayhem+64.4%4 runsStratagem+56.1%3 runsBig Bang+44.0%11 runsCalamity+39.4%4 runsDebt+39.4%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Strike Win Rate by Class

Strike is drafted only by the Regent, where it holds a 10.6% win rate across 165 runs.

The Regentappears in 99.4% of its runs (165 tracked)

Best Relics for Strike

Strike pairs best with the relics Ornamental Fan (+89.4%), Daughter of the Wind (+89.4%), and Beating Remnant (+56.1%), ranked by win-rate lift.

Ornamental Fan+89.4%3 runsDaughter of the Wind+89.4%3 runsBeating Remnant+56.1%3 runsBowler Hat+56.1%3 runsDolly's Mirror+56.1%3 runsBing Bong+56.1%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Strike Card Details

Strike is a basic attack costing 1 energy; it’s upgraded in 3.1% of runs and usually picked up by floor 1.

Deal 6 damage.

Upgrade: +3 Damage

What Ends Runs with Strike

Strike’s most common run-enders are Terror Eel Elite (7.3%), Vantom Boss (7.3%), and Skulking Colony Elite (6.1%).

• Terror Eel Elite7.3% of runs
• Vantom Boss7.3% of runs
• Skulking Colony Elite6.1% of runs
• Waterfall Giant Boss4.8% of runs
• Ceremonial Beast Boss4.2% of runs

See Also

Compare Strike with the rest of the best Slay the Spire 2 cards, relics, and classes below.