Strike Attack

Is Strike good in Slay the Spire 2?

Strike is a basic Regent attack in Slay the Spire 2. In combat it resolves as: Deal 6 damage. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 4215 recorded runs, decks running it win 11.3% of the time, trailing the 14.3% average by 3.0%. It’s a popular draft, appearing in 15.6% of eligible decks. Regent players keep it in 90.2% of their runs, so it’s a familiar sight in those decks. On average it shows up 3.3 times in the decks that take it.

It performs best next to Mad Science — together they post a +44.3% swing in win rate. It also has strong chemistry with the relic History Course, which moves its win rate by +54.9%. At 1 energy, it’s upgraded in 6.1% of runs and usually joins the deck around floor 1.

Upgraded, it gains +3 Damage, which is why so many decks invest a rest-site upgrade in it. That’s 464 wins, 3657 deaths, and 94 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Decimillipede Elite, which closes out 3.5% of its appearances. Read on for Strike’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

When to Pick Up Strike

Strike is strongest when it joins the deck in Starting deck, where runs win 11.2% across 4210 runs — one of 1 recorded pickup windows.

Win rate of runs by the act Strike entered the deck. Acts that have not reached the sample floor show their run count only.

Best Cards to Pair with Strike

Ranked by win-rate lift, Strike performs best alongside Mad Science (+44.3%), Bad Luck (+39.2%), and Enthralled (+37.8%).

Mad Science+44.3%145 runsBad Luck+39.2%20 runsEnthralled+37.8%32 runsMaster of Strategy+32.3%27 runsApotheosis+30.9%33 runsMayhem+30.9%33 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Strike Win Rate by Class

Strike is drafted only by the Regent, where it holds a 11.3% win rate across 4215 runs.

The Regentappears in 90.2% of its runs (4215 tracked)

Best Relics for Strike

Strike pairs best with the relics History Course (+54.9%), Sai (+49.4%), and Sword of Jade (+47.9%), ranked by win-rate lift.

History Course+54.9%28 runsSai+49.4%43 runsSword of Jade+47.9%46 runsMusic Box+44.3%28 runsTri-Boomerang+42.4%35 runsCrossbow+41.7%28 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Strike Card Details

Strike is a basic attack costing 1 energy; it’s upgraded in 6.1% of runs and usually picked up by floor 1.

Deal 6 damage.

Upgrade: +3 Damage

What Ends Runs with Strike

Strike’s most common run-enders are Decimillipede Elite (3.5%), Knowledge Demon Boss (3.3%), and Phrog Parasite Elite (3.3%).

• Decimillipede Elite3.5% of runs
• Knowledge Demon Boss3.3% of runs
• Phrog Parasite Elite3.3% of runs
• Infested Prisms Elite2.9% of runs
• Kaiser Crab Boss2.9% of runs

See Also

Compare Strike with the rest of the best Slay the Spire 2 cards, relics, and classes below.