Master of Strategy•Skill

Is Master of Strategy good in Slay the Spire 2?

Master of Strategy is a rare Colorless skill in Slay the Spire 2. In combat it resolves as: Draw cards. It ranks among the strongest cards its class can draft right now, earning a spot at S tier in our Slay the Spire 2 card tier list.

Across 55 recorded runs, decks running it win 50.0% of the time, comfortably clear of the 18.9% average, by 31.1%. It’s a more selective pick, turning up in just 1.4% of decks that could run it. Necrobinder players keep it in 0.7% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.0 times in the decks that take it.

It performs best next to Reflex — together they post a +14.3% swing in win rate. It also has strong chemistry with the relic Tiny Mailbox, which moves its win rate by +16.7%. At 0 energy, it’s upgraded in 28.1% of runs and usually joins the deck around floor 24.

Upgraded, it gains +1 Cards, which is why so many decks invest a rest-site upgrade in it. That’s 24 wins, 24 deaths, and 7 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Test Subject Boss, which closes out 9.1% of its appearances. Read on for Master of Strategy’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Colorless run.

Best Cards to Pair with Master of Strategy

Ranked by win-rate lift, Master of Strategy performs best alongside Reflex (+14.3%), Defy (+14.3%), and Inflame (+12.5%).

Reflex+14.3%5 runsDefy+14.3%4 runsInflame+12.5%6 runsBlack Hole+11.5%3 runsBackstab+11.5%3 runsFlame Barrier+11.5%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Master of Strategy Win Rate by Class

Master of Strategy is played across 5 classes, led by Necrobinder (80.0%), Regent (57.1%), and Ironclad (46.7%) by win rate.

The Necrobinder80.0%6 runsThe Regent57.1%7 runsThe Ironclad46.7%16 runsThe Silent43.8%18 runsThe Defect40.0%8 runs

Best Relics for Master of Strategy

Master of Strategy pairs best with the relics Tiny Mailbox (+16.7%), Anchor (+15.2%), and Happy Flower (+14.7%), ranked by win-rate lift.

Tiny Mailbox+16.7%5 runsAnchor+15.2%14 runsHappy Flower+14.7%7 runsMiniature Cannon+14.3%6 runsStrawberry+13.2%9 runsRed Mask+13.2%10 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Master of Strategy Card Details

Master of Strategy is a rare skill costing 0 energy; it’s upgraded in 28.1% of runs and usually picked up by floor 24.

Draw cards.

Upgrade: +1 Cards

What Ends Runs with Master of Strategy

Master of Strategy’s most common run-enders are Test Subject Boss (9.1%), Kaiser Crab Boss (5.5%), and Knowledge Demon Boss (3.6%).

• Test Subject Boss9.1% of runs
• Kaiser Crab Boss5.5% of runs
• Knowledge Demon Boss3.6% of runs
• Infested Prisms Elite3.6% of runs
• Aeonglass Boss3.6% of runs

See Also

Compare Master of Strategy with the rest of the best Slay the Spire 2 cards, relics, and classes below.