Mayhem•Power

Is Mayhem good in Slay the Spire 2?

In Slay the Spire 2, Mayhem is a rare power from the Colorless card pool. Its effect: At the start of your turn, play the top card of your Draw Pile. Right now it’s a premium pick that sits at S tier — one of the better cards you can add to a deck this run.

Over 44 tracked runs its win rate sits at 52.5%, 33.5% ahead of the 19.0% all-deck baseline. It sees niche play, included in only 1.2% of eligible runs. Within Necrobinder runs it’s drafted 1.1% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Gather Light, which lifts its win rate by +11.6% when the two share a deck. On the relic side, Mercury Hourglass is its standout companion, worth a +15.8% win-rate swing alongside it. It costs 2 energy, gets upgraded 61.7% of the time, and tends to be picked up near floor 21.

Upgrading the card adds -1 EnergyCost to its stat line. Of the runs that drafted it, 21 ended in victory against 19 deaths and 4 abandons. Its most common run-ender is Queen Boss, finishing 6.8% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Mayhem fits a Colorless deck.

Best Cards to Pair with Mayhem

Mayhem’s strongest card pairings so far are Gather Light (+11.6%), Astral Pulse (+11.0%), and Particle Wall (+11.0%), each shown with the win-rate lift it adds.

Gather Light+11.6%6 runsAstral Pulse+11.0%3 runsParticle Wall+11.0%3 runsReflex+11.0%3 runsSpectrum Shift+11.0%3 runsStardust+11.0%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Mayhem Win Rate by Class

Of the 5 classes that draft Mayhem, it performs best with Necrobinder (62.5%), Regent (62.5%), and Defect (60.0%).

The Necrobinder62.5%9 runsThe Regent62.5%8 runsThe Defect60.0%5 runsThe Silent50.0%10 runsThe Ironclad36.4%12 runs

Best Relics for Mayhem

The relics that swing Mayhem’s win rate the most are Mercury Hourglass (+15.8%), Vajra (+13.7%), and Orichalcum (+13.7%), with each lift shown.

Mercury Hourglass+15.8%5 runsVajra+13.7%7 runsOrichalcum+13.7%8 runsPendulum+13.7%7 runsCandelabra+13.6%4 runsRipple Basin+13.6%5 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Mayhem Card Details

A 2-energy rare power, Mayhem is upgraded 61.7% of the time and tends to enter the deck around floor 21.

At the start of your turn, play the top card of your Draw Pile.

Upgrade: -1 EnergyCost

What Ends Runs with Mayhem

Runs holding Mayhem end most often against Queen Boss (6.8%), The Obscura Normal (6.8%), and Test Subject Boss (6.8%) — the share of its runs each accounts for is shown.

• Queen Boss6.8% of runs
• The Obscura Normal6.8% of runs
• Test Subject Boss6.8% of runs
• Construct Menagerie Normal4.5% of runs
• Vine Shambler Normal4.5% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.