Black Blood•Relic

Is Black Blood good in Slay the Spire 2?

Black Blood is a starter relic in Slay the Spire 2. While carried, it does the following: At the end of combat, heal HP. It currently underperforms most relics, sitting at F tier in our Slay the Spire 2 relic rankings.

Across 84 recorded runs, decks carrying it win 25.0% of the time, comfortably clear of the 13.9% average, by 11.1%. It’s a more situational relic, showing up in just 0.7% of runs. The class that gets the most out of it is the Ironclad, at a 25.0% win rate. Ironclad players hold onto it in 3.1% of their runs.

It combos especially well with Dominate, worth a +25.0% win-rate swing together. Another strong card to run with it is Battle Trance, worth +23.4% to its win rate. On average it’s acquired around floor 18 of a run. Its starter rarity shapes how frequently you’ll run into it.

It has 21 run wins against 63 losses in our tracked data. When runs carrying it end, the most frequent culprit is Decimillipede Elite, which closes out 8.3% of them. Read on for Black Blood’s complete card, class, and threat breakdown before you decide to pick it up.

Pick or Skip: Black Blood

Black Blood is taken in 100.0% of its 84 recorded offers, but with 84 runs picking it and 0 passing, neither side has enough decided runs for a win rate yet.

Taken 84 times out of 84 offers.

A win rate is only shown once that side clears the sample floor. Below it you get the run counts and nothing else — a 0% here would be a reporting artefact, not a result.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Black Blood

Ranked by win-rate lift, the best cards to run with Black Blood are Dominate (+25.0%), Battle Trance (+23.4%), and Thunderclap (+17.1%).

Dominate+25.0%18 runsBattle Trance+23.4%31 runsThunderclap+17.1%19 runsBully+16.2%17 runsBlood Wall+15.9%22 runsBreakthrough+15.0%15 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Black Blood Win Rate by Class

So far Black Blood is carried mainly by the Ironclad, who win 25.0% of their runs with it across 84 tracked.

The Ironcladappears in 3.1% of its runs (84 tracked)

Black Blood Details

Black Blood is a starter relic carried in 0.7% of runs and usually picked up around floor 18.

At the end of combat, heal HP.

What Ends Runs with Black Blood

Black Blood’s most common run-enders are Decimillipede Elite (8.3%), Knowledge Demon Boss (8.3%), and Infested Prisms Elite (8.3%).

• Decimillipede Elite8.3% of runs
• Knowledge Demon Boss8.3% of runs
• Infested Prisms Elite8.3% of runs
• The Insatiable Boss7.1% of runs
• Test Subject Boss7.1% of runs

See Also

Compare Black Blood with the rest of the best Slay the Spire 2 relics, cards, and classes below.