Black BloodRelic
At the end of combat, heal HP.
Is Black Blood good in Slay the Spire 2?
Black Blood is a starter relic in Slay the Spire 2. While carried, it does the following: At the end of combat, heal HP. It currently underperforms most relics, sitting at F tier in our Slay the Spire 2 relic rankings.
Across 22 recorded runs, decks carrying it win 27.3% of the time, comfortably clear of the 18.9% average, by 8.3%. It’s a more situational relic, showing up in just 0.6% of runs. The class that gets the most out of it is the Ironclad, at a 27.3% win rate. Ironclad players hold onto it in 3.1% of their runs.
It combos especially well with Rupture, worth a +72.7% win-rate swing together. Another strong card to run with it is Cruelty, worth +47.7% to its win rate. On average it’s acquired around floor 18 of a run. Its starter rarity shapes how frequently you’ll run into it.
It has 6 run wins against 16 losses in our tracked data. When runs carrying it end, the most frequent culprit is Knowledge Demon Boss, which closes out 13.6% of them. Read on for Black Blood’s complete card, class, and threat breakdown before you decide to pick it up.
Black Blood Win Rate & Pick Rate
Black Blood’s 27.3% win rate clears the 18.9% all-run average by 8.3%, the gap charted below.
Run Outcomes with Black Blood
Black Blood has 6 wins and 16 losses over 22 tracked runs (27.3% won); abandoned runs count as losses.
- Wins 27.3%
- Losses 72.7%
Best Cards with Black Blood
Ranked by win-rate lift, the best cards to run with Black Blood are Rupture (+72.7%), Cruelty (+47.7%), and Breakthrough (+47.7%).
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Black Blood Win Rate by Class
So far Black Blood is carried mainly by the Ironclad, who win 27.3% of their runs with it across 22 tracked.
The Ironcladappears in 3.1% of its runs (22 tracked)Black Blood Details
Black Blood is a starter relic carried in 0.6% of runs and usually picked up around floor 18.
At the end of combat, heal HP.
What Ends Runs with Black Blood
Black Blood’s most common run-enders are Knowledge Demon Boss (13.6%), Decimillipede Elite (9.1%), and Infested Prisms Elite (9.1%).
- Knowledge Demon Boss13.6% of runs
- Decimillipede Elite9.1% of runs
- Infested Prisms Elite9.1% of runs
- Test Subject Boss9.1% of runs
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Black Blood – Frequently Asked Questions
Is Black Blood good in Slay the Spire 2?
Across 22 tracked runs carrying it, Black Blood wins 27.3% of the time — +8.3% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Black Blood do in Slay the Spire 2?
At the end of combat, heal HP.
How rare is Black Blood in Slay the Spire 2?
Black Blood is a Starter relic, picked up in 0.6% of tracked runs.
What is the best card to use with Black Blood?
In tracked runs, Black Blood has performed best alongside Rupture, which lifts its win rate by +72.7% over 3 runs together.
See Also
Compare Black Blood with the rest of the best Slay the Spire 2 relics, cards, and classes below.