Cassiopeia - League of Legends Champion
Win Rate
51.2%
Pick Rate
0.8%

Cassiopeiavs Pantheon

AMage
Patch26.10
Matches2,379,056
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 25, 2026
MethodologyData Methodology

Cassiopeia vs Pantheon is a decisive matchup in LoL patch 26.10. Cassiopeia wins with a 80.0% win rate (+60.0%) over Pantheon based on 5 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Pantheon matchup.

Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pantheon - 80.0% win ratePantheon(80.0%)
Cassiopeia - 80.0% win rate in this matchup
Cassiopeia
80.0% WR
VS
Pantheon vs Cassiopeia matchup - 20.0% win rate
Pantheon
20.0% WR

Who Wins the Cassiopeia vs Pantheon Matchup?

Cassiopeia wins the Cassiopeia vs Pantheon matchup
Winner
Cassiopeia
Matches: 5
80.0%
Win Rate
20.0%
5.8
CS / min
5.5
1,064
DMG / min
843
12,017
Gold / game
11,354
290
Heal / min
270
671
DMG Mitigated / min
851
1.4
CC / min
0.8
100.0%
Early Game WR
0.0%
75.0%
Late Game WR
25.0%

Cassiopeia vs Pantheon Matchup Summary

The Cassiopeia vs Pantheon matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Cassiopeia wins with a 80.0% win rate compared to Pantheon's 20.0%, giving Cassiopeia a 60.0 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Pantheon players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Cassiopeia leads by 0.6s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Pantheon and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Pantheon away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Pantheon Laning Phase Breakdown

Cassiopeia wins the laning phase against Pantheon in League of Legends

Cassiopeia is favored during the laning phase against Pantheon, winning 4 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.8Cassiopeia
5.5Pantheon
Cassiopeia and Pantheon farm at nearly identical rates in this matchup, with only a 0.2 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
1,064Cassiopeia
843Pantheon
Cassiopeia heavily out-damages Pantheon by 221 DMG/min, dominating both short trades and all-in fights. Pantheon should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Cassiopeia's sustained damage advantage take over.
Economy
12,017Cassiopeia
11,354Pantheon
Cassiopeia earns 663 more gold per game than Pantheon, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Cassiopeia slightly faster item completions.
Utility
1.4Cassiopeia
0.8Pantheon
Cassiopeia provides 0.6 seconds more crowd control per minute than Pantheon, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Cassiopeia coordinate with their jungler and control the pace of skirmishes.
Sustain
961Cassiopeia
1,121Pantheon
Pantheon vastly out-sustains Cassiopeia, healing and mitigating 160 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Cassiopeia is forced to recall. Building grievous wounds early is essential for Cassiopeia, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Pantheon

Swiftmarch is the optimal boots choice against Pantheon, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Pantheon are Rod of Ages, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Pantheon. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Pantheon matchup.

Early Game vs Late Game

Early Game
Cassiopeia
100.0%
+100.0% advantage
Cassiopeia early game win rateCassiopeia100.0%
Pantheon early game win ratePantheon0.0%
Late Game
Cassiopeia
75.0%
+50.0% advantage
Cassiopeia late game win rateCassiopeia75.0%
Pantheon late game win ratePantheon25.0%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Pantheon. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Pantheon. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Pantheon players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Pantheon

Sorcery rune tree - Cassiopeia primary runes vs PantheonSorcery
Deathfire Touch - best Cassiopeia rune vs PantheonManaflow Band - best Cassiopeia rune vs PantheonTranscendence - best Cassiopeia rune vs PantheonScorch - best Cassiopeia rune vs Pantheon
Precision rune tree - Cassiopeia secondary runes vs PantheonPrecision
Coup de Grace - best Cassiopeia rune vs PantheonPresence of Mind - best Cassiopeia rune vs Pantheon
100.0% WR

Running Sorcery primary with Precision secondary allows Cassiopeia to press their advantage against Pantheon, amplifying the strengths that make this a favorable matchup.


Cassiopeia matchup data for League of Legends patch 26.10. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.55%586.482311,86463.6%36.1%
46.81%476.891811,96044.4%48.3%
51.06%476.574611,16357.1%46.1%
37.78%456.986911,13340.9%34.8%
53.49%436.680510,95856.5%50.0%
51.43%356.876712,32077.8%42.3%
26.47%346.276711,33415.4%33.3%
53.13%326.891611,16038.5%63.2%
70.97%316.890213,39363.6%75.0%
54.84%316.176810,21735.7%70.6%
40.00%306.270011,38044.4%38.1%
50.00%306.085711,74435.7%62.5%
55.56%276.577611,55236.4%68.8%
61.54%266.397411,51845.5%73.3%
61.54%266.283510,70972.7%53.3%
42.31%266.385111,68440.0%43.8%
37.50%246.582611,34425.0%43.8%
54.17%246.691611,23538.5%72.7%
45.83%246.869811,75340.0%50.0%
52.17%236.688212,79472.7%33.3%
43.48%236.668310,32050.0%36.4%
42.86%216.383711,13940.0%45.5%
28.57%216.494412,06410.0%45.5%
57.89%197.188111,38866.7%50.0%
52.63%197.380111,76270.0%33.3%
66.67%186.885111,46366.7%66.7%
50.00%186.769311,02533.3%66.7%
61.11%186.51,01113,86980.0%53.9%
68.75%166.891512,42466.7%70.0%
25.00%166.797510,88720.0%33.3%
40.00%156.481212,48240.0%40.0%
46.67%156.688011,31233.3%66.7%
53.33%157.075810,33175.0%28.6%
46.67%155.68379,41857.1%37.5%
60.00%156.777511,88950.0%66.7%
53.33%156.495915,25280.0%40.0%
42.86%146.584314,39960.0%33.3%
42.86%145.699912,81040.0%44.4%
57.14%146.874510,70466.7%40.0%
46.15%136.177311,11675.0%33.3%
46.15%136.275213,06525.0%55.6%
38.46%136.888612,28040.0%37.5%
38.46%136.587112,22925.0%44.4%
46.15%136.367710,36550.0%42.9%
33.33%126.584611,52540.0%28.6%
75.00%126.095312,12566.7%77.8%
33.33%127.188613,28133.3%33.3%
40.00%106.774810,25150.0%33.3%
70.00%106.276013,23466.7%71.4%
40.00%106.695112,29625.0%50.0%
30.00%105.07719,95420.0%40.0%
60.00%106.859610,76260.0%60.0%
33.33%96.66649,94340.0%25.0%
55.56%95.89409,89180.0%25.0%
55.56%96.264312,38675.0%40.0%
37.50%86.593711,12350.0%25.0%
75.00%86.869212,90166.7%80.0%
50.00%87.693613,63150.0%50.0%
62.50%85.073812,673100.0%57.1%
42.86%76.281310,95333.3%50.0%
42.86%76.79509,39650.0%33.3%
28.57%76.091914,773100.0%16.7%
42.86%76.584413,416100.0%33.3%
57.14%77.388712,39066.7%50.0%
57.14%76.783713,61266.7%50.0%
57.14%76.78359,91660.0%50.0%
42.86%74.775111,3020.0%50.0%
42.86%77.097912,94750.0%33.3%
50.00%68.572911,19875.0%0.0%
66.67%66.685711,941100.0%33.3%
50.00%65.41,10610,45266.7%33.3%
33.33%65.194012,71350.0%25.0%
50.00%66.468310,56750.0%50.0%
50.00%67.585610,70466.7%33.3%
50.00%66.01,00311,64566.7%33.3%
50.00%66.678211,7340.0%60.0%
50.00%66.880010,45850.0%50.0%
50.00%66.490011,37166.7%33.3%
80.00%55.91,14210,330100.0%75.0%
80.00%55.81,06412,017100.0%75.0%
20.00%55.86868,91825.0%0.0%
80.00%56.568811,435100.0%0.0%
40.00%57.193713,62933.3%50.0%
60.00%56.695214,593100.0%50.0%
60.00%56.262910,9320.0%100.0%
40.00%56.31,0999,66750.0%33.3%
20.00%53.55436,59525.0%0.0%
60.00%57.81,18313,86166.7%50.0%
60.00%57.797711,450100.0%33.3%
40.00%56.770313,7890.0%50.0%
40.00%56.782711,93250.0%33.3%
60.00%55.986912,342100.0%50.0%
60.00%57.479812,16550.0%66.7%
100.00%57.294613,607100.0%100.0%

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Cassiopeia vs Pantheon - Frequently Asked Questions

How does Cassiopeia do against Pantheon in League of Legends?

Cassiopeia wins the Cassiopeia vs Pantheon matchup with a 80.0% win rate compared to Pantheon's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Cassiopeia do against Pantheon in the early game?

In the early game, Cassiopeia has the advantage against Pantheon with a 100.0% win rate versus 0.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Pantheon in the late game?

In the late game, Cassiopeia takes over the Cassiopeia vs Pantheon matchup with a 75.0% win rate compared to 25.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Pantheon matchup?

Cassiopeia wins the matchup against Pantheon with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Cassiopeia build against Pantheon?

The best Cassiopeia build against Pantheon includes Rod of Ages, Liandry's Torment, Rylai's Crystal Scepter with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Pantheon?

The best Cassiopeia runes against Pantheon use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Pantheon matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Pantheon?

Yes, Cassiopeia has a favorable matchup against Pantheon with a 80.0% win rate. Cassiopeia strongly counters Pantheon in lane based on current patch 26.10 data.

How do I play Cassiopeia against Pantheon?

When playing Cassiopeia against Pantheon, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.