Cassiopeiavs Lissandra
Cassiopeia vs Lissandra is a decisive matchup in LoL patch 26.10. Cassiopeia wins with a 53.9% win rate (+7.7%) over Lissandra based on 26 games. Lissandra wins the early laning phase while Cassiopeia scales better into the late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Lissandra matchup.
Cassiopeia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Lissandra(53.9%)Who Wins the Cassiopeia vs Lissandra Matchup?
Cassiopeia vs Lissandra Matchup Summary
The Cassiopeia vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 26 recent matches analyzed, Cassiopeia wins with a 53.9% win rate compared to Lissandra's 46.1%, giving Cassiopeia a 7.7 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Cassiopeia outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Cassiopeia reaches their power spikes, while Cassiopeia should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Cassiopeia leads by 260 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Cassiopeia vs Lissandra Laning Phase Breakdown
Cassiopeia is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.
Best Cassiopeia Build Against Lissandra
Immortal Path is the optimal boots choice against Lissandra, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Lissandra are Rod of Ages, Liandry's Torment and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 60.0% win rate across 5 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Lissandra matchup.
Early Game vs Late Game
Cassiopeia42.9%Lissandra57.1%Cassiopeia57.9%Lissandra42.1%Lissandra dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Cassiopeia. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Cassiopeia is far superior in the late game (25+ minutes), boasting a 57.9% win rate — 15.8 points above Lissandra. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.
This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Cassiopeia reaches their scaling breakpoints. If Cassiopeia survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.
Best Cassiopeia Runes Against Lissandra
Sorcery
Precision
Running Sorcery primary with Precision secondary allows Cassiopeia to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.
Cassiopeia matchup data for League of Legends patch 26.10. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 44.07% | 59 | 6.5 | 810 | 10,866 | 36.7% | 51.7% | |
| 44.64% | 56 | 6.7 | 877 | 11,670 | 58.3% | 34.4% | |
| 51.06% | 47 | 6.7 | 924 | 11,384 | 39.1% | 62.5% | |
| 42.55% | 47 | 6.3 | 776 | 12,324 | 73.3% | 28.1% | |
| 54.76% | 42 | 6.6 | 832 | 12,735 | 61.5% | 51.7% | |
| 57.89% | 38 | 6.1 | 761 | 10,133 | 52.4% | 64.7% | |
| 36.11% | 36 | 6.5 | 785 | 12,199 | 21.4% | 45.5% | |
| 39.39% | 33 | 6.9 | 766 | 11,592 | 46.7% | 33.3% | |
| 48.48% | 33 | 6.7 | 1,038 | 12,028 | 42.9% | 52.6% | |
| 56.25% | 32 | 6.4 | 754 | 10,778 | 50.0% | 62.5% | |
| 46.67% | 30 | 6.8 | 1,002 | 11,393 | 35.3% | 61.5% | |
| 36.67% | 30 | 6.2 | 821 | 11,816 | 35.7% | 37.5% | |
| 41.38% | 29 | 6.5 | 791 | 12,064 | 37.5% | 42.9% | |
| 58.62% | 29 | 6.8 | 837 | 11,930 | 80.0% | 47.4% | |
| 53.57% | 28 | 6.4 | 873 | 11,401 | 43.8% | 66.7% | |
| 44.44% | 27 | 6.3 | 774 | 11,548 | 33.3% | 53.3% | |
| 53.85% | 26 | 6.6 | 927 | 13,226 | 42.9% | 57.9% | |
| 36.00% | 25 | 5.8 | 790 | 11,284 | 18.2% | 50.0% | |
| 48.00% | 25 | 6.2 | 901 | 12,620 | 28.6% | 55.6% | |
| 37.50% | 24 | 6.7 | 902 | 12,216 | 45.5% | 30.8% | |
| 58.33% | 24 | 6.7 | 769 | 10,761 | 66.7% | 50.0% | |
| 58.33% | 24 | 5.6 | 866 | 12,014 | 50.0% | 62.5% | |
| 45.83% | 24 | 5.6 | 949 | 11,595 | 30.0% | 57.1% | |
| 39.13% | 23 | 6.4 | 893 | 12,929 | 33.3% | 42.9% | |
| 45.45% | 22 | 6.9 | 747 | 11,241 | 44.4% | 46.1% | |
| 40.91% | 22 | 6.1 | 787 | 11,511 | 44.4% | 38.5% | |
| 50.00% | 22 | 5.9 | 813 | 10,670 | 50.0% | 50.0% | |
| 38.10% | 21 | 6.8 | 812 | 11,505 | 55.6% | 25.0% | |
| 61.90% | 21 | 6.8 | 903 | 12,814 | 60.0% | 62.5% | |
| 23.81% | 21 | 5.5 | 807 | 11,529 | 40.0% | 18.8% | |
| 52.63% | 19 | 7.2 | 870 | 11,162 | 50.0% | 55.6% | |
| 33.33% | 18 | 6.0 | 651 | 12,136 | 14.3% | 45.5% | |
| 55.56% | 18 | 6.4 | 880 | 11,398 | 60.0% | 53.9% | |
| 33.33% | 18 | 6.1 | 872 | 13,556 | 50.0% | 25.0% | |
| 47.06% | 17 | 5.9 | 651 | 10,672 | 57.1% | 40.0% | |
| 58.82% | 17 | 6.8 | 919 | 12,158 | 75.0% | 44.4% | |
| 50.00% | 16 | 6.7 | 1,078 | 11,022 | 60.0% | 33.3% | |
| 37.50% | 16 | 6.7 | 763 | 12,024 | 0.0% | 54.5% | |
| 43.75% | 16 | 6.6 | 749 | 9,081 | 41.7% | 50.0% | |
| 66.67% | 15 | 6.4 | 774 | 11,624 | 57.1% | 75.0% | |
| 40.00% | 15 | 6.5 | 842 | 12,012 | 50.0% | 28.6% | |
| 28.57% | 14 | 6.5 | 741 | 11,027 | 0.0% | 44.4% | |
| 42.86% | 14 | 6.1 | 968 | 12,973 | 57.1% | 28.6% | |
| 69.23% | 13 | 6.6 | 805 | 11,351 | 62.5% | 80.0% | |
| 46.15% | 13 | 4.9 | 695 | 9,754 | 28.6% | 66.7% | |
| 50.00% | 12 | 5.5 | 638 | 10,094 | 66.7% | 0.0% | |
| 66.67% | 12 | 6.5 | 774 | 12,695 | 66.7% | 66.7% | |
| 18.18% | 11 | 7.2 | 962 | 11,832 | 33.3% | 0.0% | |
| 54.55% | 11 | 7.5 | 983 | 12,861 | 80.0% | 33.3% | |
| 30.00% | 10 | 6.3 | 802 | 10,866 | 40.0% | 20.0% | |
| 40.00% | 10 | 6.8 | 779 | 10,111 | 66.7% | 0.0% | |
| 50.00% | 10 | 6.4 | 862 | 9,878 | 50.0% | 50.0% | |
| 70.00% | 10 | 5.6 | 806 | 10,688 | 75.0% | 66.7% | |
| 50.00% | 10 | 6.7 | 849 | 11,450 | 62.5% | 0.0% | |
| 66.67% | 9 | 5.8 | 945 | 12,848 | 75.0% | 60.0% | |
| 44.44% | 9 | 6.1 | 698 | 9,844 | 60.0% | 25.0% | |
| 62.50% | 8 | 6.6 | 668 | 9,949 | 75.0% | 50.0% | |
| 62.50% | 8 | 6.9 | 1,019 | 11,214 | 60.0% | 66.7% | |
| 62.50% | 8 | 7.0 | 1,172 | 12,102 | 50.0% | 100.0% | |
| 25.00% | 8 | 6.3 | 720 | 14,006 | 100.0% | 0.0% | |
| 12.50% | 8 | 6.0 | 820 | 9,227 | 20.0% | 0.0% | |
| 75.00% | 8 | 6.4 | 842 | 13,876 | 100.0% | 66.7% | |
| 50.00% | 8 | 7.1 | 1,020 | 11,354 | 66.7% | 40.0% | |
| 75.00% | 8 | 7.3 | 1,016 | 14,878 | 50.0% | 83.3% | |
| 57.14% | 7 | 6.2 | 909 | 12,245 | 50.0% | 100.0% | |
| 28.57% | 7 | 5.8 | 803 | 7,083 | 66.7% | 0.0% | |
| 42.86% | 7 | 5.6 | 897 | 11,056 | 100.0% | 20.0% | |
| 42.86% | 7 | 6.5 | 1,113 | 12,379 | 33.3% | 50.0% | |
| 71.43% | 7 | 6.3 | 854 | 10,957 | 60.0% | 100.0% | |
| 42.86% | 7 | 5.7 | 909 | 14,290 | 0.0% | 50.0% | |
| 71.43% | 7 | 6.8 | 939 | 13,148 | 66.7% | 75.0% | |
| 42.86% | 7 | 6.4 | 725 | 9,266 | 20.0% | 100.0% | |
| 42.86% | 7 | 6.5 | 792 | 11,926 | 0.0% | 75.0% | |
| 57.14% | 7 | 7.2 | 670 | 7,523 | 50.0% | 100.0% | |
| 28.57% | 7 | 6.2 | 947 | 13,052 | 100.0% | 16.7% | |
| 100.00% | 7 | 7.5 | 1,273 | 14,401 | 100.0% | 100.0% | |
| 50.00% | 6 | 5.4 | 913 | 9,822 | 50.0% | 50.0% | |
| 66.67% | 6 | 5.6 | 548 | 8,515 | 66.7% | 66.7% | |
| 66.67% | 6 | 6.2 | 812 | 13,060 | 100.0% | 50.0% | |
| 50.00% | 6 | 7.1 | 875 | 13,348 | 0.0% | 75.0% | |
| 33.33% | 6 | 6.3 | 769 | 13,980 | 0.0% | 40.0% | |
| 50.00% | 6 | 7.9 | 773 | 9,944 | 66.7% | 33.3% | |
| 66.67% | 6 | 6.1 | 999 | 14,248 | 0.0% | 80.0% | |
| 33.33% | 6 | 6.4 | 764 | 10,880 | 0.0% | 50.0% | |
| 66.67% | 6 | 6.2 | 723 | 13,072 | 100.0% | 50.0% | |
| 20.00% | 5 | 6.2 | 811 | 11,565 | 0.0% | 25.0% | |
| 60.00% | 5 | 6.7 | 952 | 14,302 | 50.0% | 100.0% | |
| 100.00% | 5 | 7.2 | 859 | 12,579 | 100.0% | 100.0% | |
| 20.00% | 5 | 6.0 | 873 | 14,136 | 0.0% | 25.0% | |
| 20.00% | 5 | 7.3 | 961 | 13,692 | 33.3% | 0.0% | |
| 20.00% | 5 | 7.3 | 684 | 11,598 | 25.0% | 0.0% | |
| 40.00% | 5 | 7.2 | 852 | 11,058 | 50.0% | 33.3% | |
| 60.00% | 5 | 6.5 | 863 | 13,732 | 50.0% | 66.7% | |
| 20.00% | 5 | 7.2 | 982 | 10,463 | 50.0% | 0.0% | |
| 60.00% | 5 | 5.5 | 814 | 11,974 | 66.7% | 50.0% | |
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Cassiopeia vs Lissandra - Frequently Asked Questions
How does Cassiopeia do against Lissandra in League of Legends?
Cassiopeia wins the Cassiopeia vs Lissandra matchup with a 53.9% win rate compared to Lissandra's 46.1%, a 7.7 percentage point difference. This data is based on 26 recent ranked games in patch 26.10.
How does Cassiopeia do against Lissandra in the early game?
In the early game, Lissandra has the advantage against Cassiopeia with a 57.1% win rate versus 42.9%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Cassiopeia do against Lissandra in the late game?
In the late game, Cassiopeia takes over the Cassiopeia vs Lissandra matchup with a 57.9% win rate compared to 42.1%. Cassiopeia scales better into team fights and objective contests after 25 minutes.
Who wins the Cassiopeia vs Lissandra matchup?
Cassiopeia wins the matchup against Lissandra with a 53.9% win rate in League of Legends patch 26.10. The 7.7 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 26 games analyzed.
What is the best Cassiopeia build against Lissandra?
The best Cassiopeia build against Lissandra includes Rod of Ages, Liandry's Torment, Rylai's Crystal Scepter with Immortal Path. This build achieves a 60.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Cassiopeia runes against Lissandra?
The best Cassiopeia runes against Lissandra use the Sorcery primary tree with Precision secondary. This rune setup achieves a 60.0% win rate in the Cassiopeia vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.
Does Cassiopeia counter Lissandra?
Yes, Cassiopeia has a favorable matchup against Lissandra with a 53.9% win rate. Cassiopeia strongly counters Lissandra in lane based on current patch 26.10 data.
How do I play Cassiopeia against Lissandra?
When playing Cassiopeia against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Lissandra. Build the recommended items and runes for this specific matchup for the best results.