Cassiopeia - League of Legends Champion
Win Rate
50.3%
Pick Rate
0.7%

Cassiopeiavs Twisted Fate

BMage
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Cassiopeia vs Twisted Fate is a decisive matchup in LoL patch 26.5. Cassiopeia wins with a 100.0% win rate (+100.0%) over Twisted Fate based on 5 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Twisted Fate matchup.

Cassiopeia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Twisted Fate - 100.0% win rateTwisted Fate(100.0%)
Cassiopeia - 100.0% win rate in this matchup
Cassiopeia
100.0% WR
VS
Twisted Fate vs Cassiopeia matchup - 0.0% win rate
Twisted Fate
0.0% WR

Who Wins the Cassiopeia vs Twisted Fate Matchup?

Cassiopeia wins the Cassiopeia vs Twisted Fate matchup
Winner
Cassiopeia
Matches: 5
100.0%
Win Rate
0.0%
7.0
CS / min
6.7
789
DMG / min
850
13,086
Gold / game
12,954
352
Heal / min
226
623
DMG Mitigated / min
539
1.2
CC / min
1.4
100.0%
Early Game WR
0.0%
100.0%
Late Game WR
0.0%

Cassiopeia vs Twisted Fate Matchup Summary

The Cassiopeia vs Twisted Fate matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Cassiopeia wins with a 100.0% win rate compared to Twisted Fate's 0.0%, giving Cassiopeia a 100.0 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Twisted Fate players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 211 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Twisted Fate and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Twisted Fate away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Cassiopeia vs Twisted Fate Laning Phase Breakdown

Cassiopeia wins the laning phase against Twisted Fate in League of Legends

Cassiopeia is favored during the laning phase against Twisted Fate, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
7.0Cassiopeia
6.7Twisted Fate
Cassiopeia edges out Twisted Fate by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Cassiopeia.
Damage
789Cassiopeia
850Twisted Fate
Twisted Fate deals 61 more champion damage per minute than Cassiopeia. While noticeable in extended trades, this gap can be offset by Cassiopeia choosing favorable fight windows, such as engaging when Twisted Fate's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
13,086Cassiopeia
12,954Twisted Fate
Cassiopeia and Twisted Fate generate nearly equal gold per game, with just a 132 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Cassiopeia
1.4Twisted Fate
Both Cassiopeia and Twisted Fate provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
976Cassiopeia
765Twisted Fate
Cassiopeia vastly out-sustains Twisted Fate, healing and mitigating 211 more damage per minute. This massive durability gap means Cassiopeia can absorb significant punishment and remain in lane while Twisted Fate is forced to recall. Building grievous wounds early is essential for Twisted Fate, and focusing on burst trade patterns rather than sustained fights is critical.

Best Cassiopeia Build Against Twisted Fate

Swiftmarch is the optimal boots choice against Twisted Fate, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Twisted Fate are Rod of Ages, Liandry's Torment and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Twisted Fate. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Twisted Fate matchup.

Early Game vs Late Game

Early Game
Cassiopeia
100.0%
+100.0% advantage
Cassiopeia early game win rateCassiopeia100.0%
Twisted Fate early game win rateTwisted Fate0.0%
Late Game
Cassiopeia
100.0%
+100.0% advantage
Cassiopeia late game win rateCassiopeia100.0%
Twisted Fate late game win rateTwisted Fate0.0%

Cassiopeia dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Twisted Fate. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Cassiopeia is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Twisted Fate. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.

Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Twisted Fate players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Cassiopeia Runes Against Twisted Fate

Sorcery rune tree - Cassiopeia primary runes vs Twisted FateSorcery
Phase Rush - best Cassiopeia rune vs Twisted FateManaflow Band - best Cassiopeia rune vs Twisted FateTranscendence - best Cassiopeia rune vs Twisted FateScorch - best Cassiopeia rune vs Twisted Fate
Precision rune tree - Cassiopeia secondary runes vs Twisted FatePrecision
Coup de Grace - best Cassiopeia rune vs Twisted FatePresence of Mind - best Cassiopeia rune vs Twisted Fate
100.0% WR

Running Sorcery primary with Precision secondary allows Cassiopeia to press their advantage against Twisted Fate, amplifying the strengths that make this a favorable matchup.


Cassiopeia matchup data for League of Legends patch 26.5. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Cassiopeia matchup win rates and stats in League of Legends patch 26.5
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
40.54%376.770111,21235.3%45.0%
73.08%266.489211,87266.7%78.6%
47.37%196.77859,87666.7%14.3%
50.00%166.277611,82040.0%54.5%
81.25%166.790213,12485.7%77.8%
50.00%146.493014,221100.0%36.4%
35.71%146.785511,80622.2%60.0%
50.00%145.987612,81620.0%66.7%
30.77%136.580313,74133.3%30.0%
46.15%136.67449,90040.0%50.0%
46.15%136.268712,18975.0%33.3%
61.54%135.88009,47257.1%66.7%
58.33%127.288112,49933.3%66.7%
58.33%126.686111,17133.3%83.3%
50.00%127.688211,65871.4%20.0%
27.27%117.26329,69828.6%25.0%
40.00%106.464110,20260.0%20.0%
60.00%106.36539,46566.7%50.0%
33.33%96.81,11413,0380.0%42.9%
55.56%96.284611,12766.7%33.3%
66.67%96.888012,16766.7%66.7%
66.67%96.31,12714,36850.0%71.4%
50.00%86.267010,65333.3%60.0%
37.50%87.278810,15833.3%50.0%
50.00%85.671210,55966.7%40.0%
37.50%86.788511,60540.0%33.3%
25.00%85.377311,3690.0%33.3%
42.86%77.578110,70550.0%33.3%
83.33%66.91,07711,883100.0%50.0%
50.00%67.496412,15733.3%66.7%
66.67%67.11,10015,3690.0%66.7%
33.33%67.47589,00440.0%0.0%
66.67%66.584410,90475.0%50.0%
66.67%65.681611,28150.0%75.0%
83.33%66.764412,117100.0%75.0%
60.00%56.57529,95966.7%50.0%
100.00%57.078913,086100.0%100.0%
40.00%55.976010,76433.3%50.0%
40.00%56.595412,8600.0%100.0%
80.00%55.890413,292100.0%66.7%
40.00%55.556610,0730.0%66.7%
40.00%57.21,01411,92050.0%33.3%
100.00%26.89507,998100.0%0.0%

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Cassiopeia vs Twisted Fate - Frequently Asked Questions

How does Cassiopeia do against Twisted Fate in League of Legends?

Cassiopeia wins the Cassiopeia vs Twisted Fate matchup with a 100.0% win rate compared to Twisted Fate's 0.0%, a 100.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.5.

How does Cassiopeia do against Twisted Fate in the early game?

In the early game, Cassiopeia has the advantage against Twisted Fate with a 100.0% win rate versus 0.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Cassiopeia do against Twisted Fate in the late game?

In the late game, Cassiopeia takes over the Cassiopeia vs Twisted Fate matchup with a 100.0% win rate compared to 0.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.

Who wins the Cassiopeia vs Twisted Fate matchup?

Cassiopeia wins the matchup against Twisted Fate with a 100.0% win rate in League of Legends patch 26.5. The 100.0 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Cassiopeia build against Twisted Fate?

The best Cassiopeia build against Twisted Fate includes Rod of Ages, Liandry's Torment, Seraph's Embrace with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Cassiopeia runes against Twisted Fate?

The best Cassiopeia runes against Twisted Fate use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Twisted Fate matchup. See the full rune breakdown in the matchup comparison above.

Does Cassiopeia counter Twisted Fate?

Yes, Cassiopeia has a favorable matchup against Twisted Fate with a 100.0% win rate. Cassiopeia strongly counters Twisted Fate in lane based on current patch 26.5 data.

How do I play Cassiopeia against Twisted Fate?

When playing Cassiopeia against Twisted Fate, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.