Nautilus - League of Legends Champion
Win Rate
49.8%
Pick Rate
4.9%

Nautilusvs Lissandra

CTankSupport
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Nautilus vs Lissandra is a decisive matchup in LoL patch 26.14. Nautilus wins with a 60.0% win rate (+20.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Nautilus scales better into the late game. Below you'll find the best Nautilus build, runes, laning stats, and strategies for the Nautilus vs Lissandra matchup.

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Nautilus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Nautilus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nautilus - 60.0% win rate in this matchup
Nautilus
60.0% WR
VS
Lissandra vs Nautilus matchup - 40.0% win rate
Lissandra
40.0% WR

Who Wins the Nautilus vs Lissandra Matchup?

Nautilus wins the Nautilus vs Lissandra matchup
Winner
Nautilus
Matches: 5
60.0%
Win Rate
40.0%
1.8
CS / min
3.1
375
DMG / min
638
10,542
Gold / game
12,160
125
Heal / min
139
1,646
DMG Mitigated / min
403
2.0
CC / min
1.8
0.0%
Early Game WR
100.0%
75.0%
Late Game WR
25.0%

Nautilus vs Lissandra Matchup Summary

The Nautilus vs Lissandra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Nautilus wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Nautilus a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Nautilus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Nautilus reaches their power spikes, while Nautilus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nautilus leads by 1,229 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nautilus players can confidently pick into Lissandra and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Lissandra away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Nautilus vs Lissandra Laning Phase Breakdown

Lissandra wins the laning phase against Nautilus in League of Legends

Lissandra is favored during the laning phase against Nautilus, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
1.8Nautilus
3.1Lissandra
Lissandra significantly out-farms Nautilus by 1.3 CS per minute, accumulating an estimated 20 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Nautilus players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
375Nautilus
638Lissandra
Lissandra heavily out-damages Nautilus by 263 DMG/min, dominating both short trades and all-in fights. Nautilus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
10,542Nautilus
12,160Lissandra
Lissandra generates a commanding 1,618 more gold per game than Nautilus. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Nautilus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
2.0Nautilus
1.8Lissandra
Both Nautilus and Lissandra provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
1,771Nautilus
542Lissandra
Nautilus vastly out-sustains Lissandra, healing and mitigating 1,229 more damage per minute. This massive durability gap means Nautilus can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Nautilus Build Against Lissandra

Mercury's Treads is the optimal boots choice against Lissandra, providing the mobility and stats Nautilus needs most in this matchup. The top-performing core items for Nautilus against Lissandra are Locket of the Iron Solari, Knight's Vow and Bandlepipes. This combination gives Nautilus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Lissandra. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Nautilus vs Lissandra matchup.

Early Game vs Late Game

Early Game
Lissandra
100.0%
+100.0% advantage
Nautilus early game win rateNautilus0.0%
Lissandra early game win rateLissandra100.0%
Late Game
Nautilus
75.0%
+50.0% advantage
Nautilus late game win rateNautilus75.0%
Lissandra late game win rateLissandra25.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Nautilus. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nautilus is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Lissandra. Extended games heavily favor Nautilus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Nautilus reaches their scaling breakpoints. If Nautilus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Nautilus Runes Against Lissandra

Resolve rune tree - Nautilus primary runes vs LissandraResolve
Aftershock - best Nautilus rune vs LissandraShield Bash - best Nautilus rune vs LissandraConditioning - best Nautilus rune vs LissandraRevitalize - best Nautilus rune vs Lissandra
Precision rune tree - Nautilus secondary runes vs LissandraPrecision
Legend: Haste - best Nautilus rune vs LissandraTriumph - best Nautilus rune vs Lissandra
50.0% WR

Running Resolve primary with Precision secondary allows Nautilus to press their advantage against Lissandra, amplifying the strengths that make this a favorable matchup.


Nautilus matchup data for League of Legends patch 26.14. The table below shows Nautilus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Nautilus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Nautilus matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
45.48%3981.13628,51449.7%42.4%
50.00%3021.23608,39141.0%56.1%
52.94%2381.13508,47856.4%50.4%
53.04%2301.13778,25848.7%57.3%
46.33%2181.13488,33455.0%39.0%
46.60%1911.13898,76242.7%49.1%
55.00%1801.13848,72748.6%59.1%
52.00%1751.13838,97551.6%52.3%
43.41%1291.13568,18149.1%38.9%
50.39%1291.14188,89447.2%52.6%
48.44%1281.03468,32551.0%46.8%
60.00%1251.13558,45556.5%63.5%
46.79%1091.13839,14850.0%44.9%
50.00%1041.14228,83245.6%53.5%
48.48%991.14478,58942.2%53.7%
49.48%971.13797,96953.5%46.3%
53.85%911.13718,58654.3%53.6%
54.55%881.03827,72355.6%53.5%
54.02%871.03708,28751.2%56.5%
44.05%841.13648,68444.7%43.5%
60.24%831.03197,93360.9%59.5%
59.26%811.03848,95053.1%63.3%
48.10%791.13557,90348.6%47.7%
59.21%761.24519,54260.7%58.3%
45.95%741.13608,01438.5%54.3%
52.17%691.03778,32353.6%51.2%
55.22%671.24089,12053.1%57.1%
36.92%651.13629,00642.9%32.4%
45.16%621.13428,48845.8%44.7%
50.00%601.13797,52151.7%48.4%
38.78%491.44229,32330.0%44.8%
41.67%481.13758,57965.0%25.0%
57.45%471.03948,26657.1%57.7%
48.89%451.13888,78042.9%51.6%
45.45%441.13768,38047.6%43.5%
31.58%381.13697,70718.8%40.9%
41.18%341.13347,30847.4%33.3%
58.62%291.14059,85357.1%59.1%
44.83%292.04689,93533.3%50.0%
40.74%271.84639,39635.7%46.1%
68.00%251.23478,59971.4%63.6%
45.45%221.04568,15250.0%40.0%
55.00%201.14028,57442.9%61.5%
52.94%171.13638,82255.6%50.0%
62.50%161.64709,60575.0%58.3%
53.33%151.13978,63650.0%53.9%
76.92%132.25308,99871.4%83.3%
50.00%121.84399,96040.0%57.1%
58.33%121.23468,24450.0%62.5%
36.36%112.35728,84216.7%60.0%
54.55%111.251111,8190.0%54.5%
18.18%110.94468,2260.0%50.0%
18.18%111.84138,53233.3%0.0%
63.64%111.04119,42433.3%75.0%
20.00%101.14048,8360.0%28.6%
77.78%91.44629,423100.0%66.7%
66.67%91.03468,749100.0%57.1%
62.50%81.33687,46050.0%75.0%
50.00%81.447911,23450.0%50.0%
62.50%81.13258,11933.3%80.0%
42.86%71.03099,52766.7%25.0%
71.43%70.44206,10180.0%50.0%
71.43%71.63947,73575.0%66.7%
50.00%60.84077,75340.0%100.0%
66.67%65.877810,43550.0%75.0%
33.33%61.237910,5680.0%33.3%
33.33%61.385814,3230.0%50.0%
83.33%62.96209,54966.7%100.0%
50.00%61.351010,76633.3%66.7%
80.00%53.667310,56950.0%100.0%
40.00%51.152510,3890.0%66.7%
60.00%51.261611,098100.0%50.0%
20.00%53.861411,6350.0%25.0%
40.00%51.84319,7990.0%66.7%
20.00%51.85369,5720.0%50.0%
80.00%51.042411,152100.0%66.7%
40.00%51.954010,779100.0%25.0%
80.00%51.64488,654100.0%50.0%
60.00%51.837510,5420.0%75.0%
0.00%52.547110,4370.0%0.0%
40.00%51.55179,720100.0%25.0%

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Nautilus vs Lissandra - Frequently Asked Questions

How does Nautilus do against Lissandra in League of Legends?

Nautilus wins the Nautilus vs Lissandra matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.14.

How does Nautilus do against Lissandra in the early game?

In the early game, Lissandra has the advantage against Nautilus with a 100.0% win rate versus 0.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Nautilus do against Lissandra in the late game?

In the late game, Nautilus takes over the Nautilus vs Lissandra matchup with a 75.0% win rate compared to 25.0%. Nautilus scales better into team fights and objective contests after 25 minutes.

Who wins the Nautilus vs Lissandra matchup?

Nautilus wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.14. The 20.0 percentage point advantage means Nautilus is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Nautilus build against Lissandra?

The best Nautilus build against Lissandra includes Locket of the Iron Solari, Knight's Vow, Bandlepipes with Mercury's Treads. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Nautilus runes against Lissandra?

The best Nautilus runes against Lissandra use the Resolve primary tree with Precision secondary. This rune setup achieves a 50.0% win rate in the Nautilus vs Lissandra matchup. See the full rune breakdown in the matchup comparison above.

Does Nautilus counter Lissandra?

Yes, Nautilus has a favorable matchup against Lissandra with a 60.0% win rate. Nautilus strongly counters Lissandra in lane based on current patch 26.14 data.

How do I play Nautilus against Lissandra?

When playing Nautilus against Lissandra, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Lissandra. Build the recommended items and runes for this specific matchup for the best results.