Vaynevs Dr. Mundo
Vayne vs Dr. Mundo is a decisive matchup in LoL patch 26.13. Vayne wins with a 64.7% win rate (+29.4%) over Dr. Mundo based on 17 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Dr. Mundo matchup.
Vayne Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Vayne vs Dr. Mundo Matchup?
Vayne vs Dr. Mundo Matchup Summary
The Vayne vs Dr. Mundo matchup is a decisive matchup in League of Legends ranked play. Based on 17 recent matches analyzed, Vayne wins with a 64.7% win rate compared to Dr. Mundo's 35.3%, giving Vayne a 29.4 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Dr. Mundo players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Dr. Mundo leads by 1,058 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Dr. Mundo and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Dr. Mundo away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Vayne vs Dr. Mundo Laning Phase Breakdown
Dr. Mundo is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Dr. Mundo holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.
Best Vayne Build Against Dr. Mundo
Berserker's Greaves is the optimal boots choice against Dr. Mundo, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Dr. Mundo are Terminus, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Dr. Mundo. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Dr. Mundo matchup.
Early Game vs Late Game
Vayne57.1%
Dr. Mundo42.9%Vayne70.0%Dr. Mundo30.0%Vayne dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Dr. Mundo. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Vayne is far superior in the late game (25+ minutes), boasting a 70.0% win rate — 40.0 points above Dr. Mundo. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.
Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Dr. Mundo players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Vayne Runes Against Dr. Mundo
Precision
Resolve
Running Precision primary with Resolve secondary allows Vayne to press their advantage against Dr. Mundo, amplifying the strengths that make this a favorable matchup.
Vayne matchup data for League of Legends patch 26.13. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 58.62% | 145 | 5.9 | 771 | 12,511 | 57.8% | 59.5% | |
| 51.75% | 143 | 5.9 | 846 | 13,098 | 52.3% | 51.3% | |
| 43.26% | 141 | 5.5 | 721 | 12,529 | 35.7% | 48.2% | |
| 52.76% | 127 | 6.3 | 823 | 12,163 | 55.0% | 50.8% | |
| 50.00% | 110 | 6.2 | 812 | 12,827 | 47.9% | 51.6% | |
| 53.27% | 107 | 6.0 | 820 | 13,023 | 54.0% | 52.9% | |
| 39.74% | 78 | 6.1 | 795 | 11,992 | 45.2% | 33.3% | |
| 42.25% | 71 | 6.2 | 879 | 13,191 | 37.9% | 45.2% | |
| 54.29% | 70 | 6.2 | 886 | 12,979 | 51.6% | 56.4% | |
| 54.69% | 64 | 6.0 | 847 | 13,371 | 50.0% | 57.9% | |
| 53.57% | 56 | 6.0 | 834 | 12,857 | 53.9% | 53.3% | |
| 50.00% | 54 | 6.0 | 808 | 11,545 | 46.4% | 53.9% | |
| 42.00% | 50 | 6.2 | 753 | 12,285 | 43.5% | 40.7% | |
| 30.43% | 46 | 6.7 | 1,063 | 11,968 | 26.1% | 34.8% | |
| 54.55% | 44 | 5.9 | 756 | 12,694 | 57.1% | 52.2% | |
| 41.03% | 39 | 6.5 | 826 | 11,715 | 40.0% | 42.9% | |
| 44.44% | 36 | 5.8 | 739 | 11,434 | 42.1% | 47.1% | |
| 41.67% | 36 | 6.2 | 995 | 12,622 | 38.9% | 44.4% | |
| 48.57% | 35 | 5.7 | 787 | 12,494 | 53.3% | 45.0% | |
| 66.67% | 33 | 6.3 | 792 | 12,055 | 64.7% | 68.8% | |
| 54.55% | 33 | 6.4 | 795 | 12,299 | 43.8% | 64.7% | |
| 43.75% | 32 | 5.3 | 639 | 10,600 | 35.7% | 50.0% | |
| 56.67% | 30 | 6.8 | 925 | 14,960 | 57.1% | 56.3% | |
| 56.67% | 30 | 5.9 | 907 | 12,705 | 42.9% | 68.8% | |
| 44.83% | 29 | 5.8 | 605 | 10,635 | 41.7% | 47.1% | |
| 46.15% | 26 | 5.9 | 989 | 11,887 | 20.0% | 62.5% | |
| 61.54% | 26 | 5.1 | 1,063 | 11,719 | 62.5% | 61.1% | |
| 42.31% | 26 | 6.0 | 897 | 13,038 | 46.7% | 36.4% | |
| 45.45% | 22 | 5.8 | 992 | 11,792 | 50.0% | 42.9% | |
| 31.82% | 22 | 5.7 | 850 | 9,690 | 33.3% | 30.0% | |
| 63.64% | 22 | 5.9 | 1,048 | 13,703 | 55.6% | 69.2% | |
| 54.55% | 22 | 5.8 | 811 | 13,789 | 66.7% | 46.1% | |
| 65.00% | 20 | 5.8 | 973 | 12,613 | 66.7% | 63.6% | |
| 52.94% | 17 | 6.1 | 826 | 13,930 | 57.1% | 50.0% | |
| 64.71% | 17 | 6.2 | 902 | 14,881 | 57.1% | 70.0% | |
| 64.71% | 17 | 5.9 | 1,481 | 11,218 | 57.1% | 70.0% | |
| 52.94% | 17 | 5.9 | 868 | 11,104 | 62.5% | 44.4% | |
| 56.25% | 16 | 6.0 | 1,010 | 10,777 | 55.6% | 57.1% | |
| 56.25% | 16 | 6.5 | 817 | 10,651 | 55.6% | 57.1% | |
| 46.67% | 15 | 6.2 | 927 | 12,799 | 60.0% | 40.0% | |
| 35.71% | 14 | 6.0 | 706 | 10,579 | 22.2% | 60.0% | |
| 42.86% | 14 | 6.2 | 944 | 12,022 | 60.0% | 33.3% | |
| 50.00% | 14 | 5.7 | 917 | 12,046 | 50.0% | 50.0% | |
| 61.54% | 13 | 6.7 | 930 | 12,377 | 80.0% | 50.0% | |
| 30.77% | 13 | 6.3 | 930 | 11,441 | 37.5% | 20.0% | |
| 23.08% | 13 | 6.1 | 706 | 9,155 | 28.6% | 16.7% | |
| 61.54% | 13 | 5.3 | 1,090 | 12,933 | 66.7% | 57.1% | |
| 38.46% | 13 | 5.4 | 825 | 11,639 | 20.0% | 50.0% | |
| 23.08% | 13 | 5.9 | 862 | 12,777 | 20.0% | 25.0% | |
| 41.67% | 12 | 5.4 | 864 | 12,753 | 50.0% | 37.5% | |
| 45.45% | 11 | 6.5 | 1,113 | 13,236 | 66.7% | 37.5% | |
| 63.64% | 11 | 6.2 | 885 | 10,690 | 40.0% | 83.3% | |
| 63.64% | 11 | 6.6 | 925 | 11,375 | 66.7% | 60.0% | |
| 45.45% | 11 | 6.6 | 868 | 12,739 | 25.0% | 57.1% | |
| 27.27% | 11 | 5.8 | 955 | 14,331 | 33.3% | 25.0% | |
| 54.55% | 11 | 6.1 | 960 | 12,901 | 60.0% | 50.0% | |
| 45.45% | 11 | 5.7 | 950 | 11,174 | 60.0% | 33.3% | |
| 45.45% | 11 | 5.8 | 736 | 11,151 | 16.7% | 80.0% | |
| 36.36% | 11 | 5.2 | 806 | 12,226 | 40.0% | 33.3% | |
| 55.56% | 9 | 6.1 | 1,001 | 10,987 | 50.0% | 66.7% | |
| 66.67% | 9 | 5.6 | 974 | 15,312 | 50.0% | 71.4% | |
| 11.11% | 9 | 6.2 | 916 | 15,190 | 33.3% | 0.0% | |
| 44.44% | 9 | 6.6 | 821 | 13,080 | 40.0% | 50.0% | |
| 33.33% | 9 | 6.2 | 800 | 13,176 | 33.3% | 33.3% | |
| 62.50% | 8 | 6.0 | 975 | 16,558 | 50.0% | 66.7% | |
| 62.50% | 8 | 6.5 | 1,341 | 13,507 | 100.0% | 40.0% | |
| 37.50% | 8 | 6.7 | 933 | 12,083 | 33.3% | 40.0% | |
| 85.71% | 7 | 6.9 | 1,048 | 15,780 | 100.0% | 80.0% | |
| 42.86% | 7 | 6.6 | 805 | 12,364 | 40.0% | 50.0% | |
| 85.71% | 7 | 7.3 | 845 | 15,317 | 0.0% | 85.7% | |
| 71.43% | 7 | 5.2 | 816 | 13,073 | 100.0% | 66.7% | |
| 28.57% | 7 | 5.7 | 711 | 9,332 | 25.0% | 33.3% | |
| 57.14% | 7 | 6.3 | 984 | 14,027 | 50.0% | 60.0% | |
| 16.67% | 6 | 6.4 | 582 | 11,487 | 33.3% | 0.0% | |
| 50.00% | 6 | 5.8 | 766 | 10,859 | 25.0% | 100.0% | |
| 33.33% | 6 | 6.6 | 920 | 13,373 | 0.0% | 40.0% | |
| 83.33% | 6 | 6.3 | 872 | 15,834 | 0.0% | 83.3% | |
| 50.00% | 6 | 7.0 | 1,124 | 12,202 | 75.0% | 0.0% | |
| 16.67% | 6 | 6.3 | 840 | 12,213 | 0.0% | 33.3% | |
| 40.00% | 5 | 5.9 | 362 | 9,930 | 33.3% | 50.0% | |
| 60.00% | 5 | 4.4 | 621 | 11,714 | 33.3% | 100.0% | |
| 80.00% | 5 | 3.7 | 971 | 17,499 | 100.0% | 75.0% | |
| 40.00% | 5 | 6.4 | 741 | 9,713 | 33.3% | 50.0% | |
| 80.00% | 5 | 5.4 | 886 | 13,365 | 100.0% | 50.0% | |
| 60.00% | 5 | 4.7 | 558 | 11,122 | 100.0% | 33.3% | |
| 20.00% | 5 | 6.1 | 1,252 | 15,172 | 0.0% | 25.0% | |
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Vayne vs Dr. Mundo - Frequently Asked Questions
How does Vayne do against Dr. Mundo in League of Legends?
Vayne wins the Vayne vs Dr. Mundo matchup with a 64.7% win rate compared to Dr. Mundo's 35.3%, a 29.4 percentage point difference. This data is based on 17 recent ranked games in patch 26.13.
How does Vayne do against Dr. Mundo in the early game?
In the early game, Vayne has the advantage against Dr. Mundo with a 57.1% win rate versus 42.9%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Vayne do against Dr. Mundo in the late game?
In the late game, Vayne takes over the Vayne vs Dr. Mundo matchup with a 70.0% win rate compared to 30.0%. Vayne scales better into team fights and objective contests after 25 minutes.
Who wins the Vayne vs Dr. Mundo matchup?
Vayne wins the matchup against Dr. Mundo with a 64.7% win rate in League of Legends patch 26.13. The 29.4 percentage point advantage means Vayne is significantly favored in this lane matchup based on 17 games analyzed.
What is the best Vayne build against Dr. Mundo?
The best Vayne build against Dr. Mundo includes Terminus, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Vayne runes against Dr. Mundo?
The best Vayne runes against Dr. Mundo use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Dr. Mundo matchup. See the full rune breakdown in the matchup comparison above.
Does Vayne counter Dr. Mundo?
Yes, Vayne has a favorable matchup against Dr. Mundo with a 64.7% win rate. Vayne strongly counters Dr. Mundo in lane based on current patch 26.13 data.
How do I play Vayne against Dr. Mundo?
When playing Vayne against Dr. Mundo, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.