Devastate•Attack

Is Devastate good in Slay the Spire 2?

In Slay the Spire 2, Devastate is an uncommon attack from the Regent card pool. Its effect: Deal 30 damage. The data flags it as a weaker pick, settling at D tier — usually one to pass on unless your deck specifically wants it.

Over 67 tracked runs its win rate sits at 25.4%, 6.5% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 1.8% of eligible runs. Within Regent runs it’s drafted 9.8% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.0 copies on average.

Its standout pairing so far is Arsenal, which lifts its win rate by +21.3% when the two share a deck. On the relic side, Pear is its standout companion, worth a +24.8% win-rate swing alongside it. It costs 1 energy, gets upgraded 32.9% of the time, and tends to be picked up near floor 12.

Upgrading the card adds +10 Damage to its stat line. Of the runs that drafted it, 16 ended in victory against 47 deaths and 4 abandons. Its most common run-ender is Vantom Boss, finishing 6.0% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Devastate fits a Regent deck.

Best Cards to Pair with Devastate

Devastate’s strongest card pairings so far are Arsenal (+21.3%), Big Bang (+19.6%), and Stardust (+16.9%), each shown with the win-rate lift it adds.

Arsenal+21.3%4 runsBig Bang+19.6%9 runsStardust+16.9%24 runsSpectrum Shift+16.1%13 runsMad Science+15.5%6 runsMonologue+15.3%11 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Devastate Win Rate by Class

Exclusive to the Regent, Devastate posts a 25.4% win rate over 67 tracked runs.

The Regentappears in 9.8% of its runs (67 tracked)

Best Relics for Devastate

The relics that swing Devastate’s win rate the most are Pear (+24.8%), Fencing Manual (+21.7%), and Horn Cleat (+21.7%), with each lift shown.

Pear+24.8%8 runsFencing Manual+21.7%6 runsHorn Cleat+21.7%6 runsVajra+21.7%7 runsMummified Hand+21.3%4 runsPendulum+20.4%13 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Devastate Card Details

A 1-energy uncommon attack, Devastate is upgraded 32.9% of the time and tends to enter the deck around floor 12.

Deal 30 damage.

Upgrade: +10 Damage

What Ends Runs with Devastate

Runs holding Devastate end most often against Vantom Boss (6.0%), Decimillipede Elite (4.5%), and The Insatiable Boss (4.5%) — the share of its runs each accounts for is shown.

• Vantom Boss6.0% of runs
• Decimillipede Elite4.5% of runs
• The Insatiable Boss4.5% of runs
• Ceremonial Beast Boss4.5% of runs
• Knowledge Demon Boss4.5% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.