Anivia - League of Legends Champion
Win Rate
48.8%
Pick Rate
2.3%

Aniviavs Vayne

FMage
Patch26.7
Matches949,984
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 19, 2026
MethodologyData Methodology

Anivia vs Vayne is a decisive matchup in LoL patch 26.7. Anivia wins with a 80.0% win rate (+60.0%) over Vayne based on 5 games. Anivia holds the advantage in both the early and late game. Below you'll find the best Anivia build, runes, laning stats, and strategies for the Anivia vs Vayne matchup.

Anivia Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Anivia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 80.0% win rateVayne(80.0%)
Anivia - 80.0% win rate in this matchup
Anivia
80.0% WR
VS
Vayne vs Anivia matchup - 20.0% win rate
Vayne
20.0% WR

Who Wins the Anivia vs Vayne Matchup?

Anivia wins the Anivia vs Vayne matchup
Winner
Anivia
Matches: 5
80.0%
Win Rate
20.0%
7.2
CS / min
6.8
668
DMG / min
915
11,841
Gold / game
12,553
194
Heal / min
235
609
DMG Mitigated / min
371
1.4
CC / min
0.4
100.0%
Early Game WR
0.0%
66.7%
Late Game WR
33.3%

Anivia vs Vayne Matchup Summary

The Anivia vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Anivia wins with a 80.0% win rate compared to Vayne's 20.0%, giving Anivia a 60.0 percentage point advantage. Anivia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Anivia leads by 1.0s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Anivia players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Anivia vs Vayne Laning Phase Breakdown

Anivia wins the laning phase against Vayne in League of Legends

Anivia is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Anivia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.2Anivia
6.8Vayne
Anivia edges out Vayne by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Anivia.
Damage
668Anivia
915Vayne
Vayne heavily out-damages Anivia by 247 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,841Anivia
12,553Vayne
Vayne earns 712 more gold per game than Anivia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
1.4Anivia
0.4Vayne
Anivia brings significantly more crowd control than Vayne, with 1.0 more seconds of CC per minute. This large utility gap makes Anivia far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
803Anivia
606Vayne
Anivia vastly out-sustains Vayne, healing and mitigating 197 more damage per minute. This massive durability gap means Anivia can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Anivia Build Against Vayne

Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Anivia needs most in this matchup. The top-performing core items for Anivia against Vayne are Rod of Ages, Liandry's Torment and Void Staff. This combination gives Anivia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Anivia vs Vayne matchup.

Early Game vs Late Game

Early Game
Anivia
100.0%
+100.0% advantage
Anivia early game win rateAnivia100.0%
Vayne early game win rateVayne0.0%
Late Game
Anivia
66.7%
+33.3% advantage
Anivia late game win rateAnivia66.7%
Vayne late game win rateVayne33.3%

Anivia dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Vayne. This lopsided early game means Anivia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Anivia is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Vayne. Extended games heavily favor Anivia, whose kit and scaling make them a dominant force in team fights and objective control.

Anivia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Anivia Runes Against Vayne

Sorcery rune tree - Anivia primary runes vs VayneSorcery
Arcane Comet - best Anivia rune vs VayneManaflow Band - best Anivia rune vs VayneTranscendence - best Anivia rune vs VayneScorch - best Anivia rune vs Vayne
Precision rune tree - Anivia secondary runes vs VaynePrecision
Coup de Grace - best Anivia rune vs VaynePresence of Mind - best Anivia rune vs Vayne
100.0% WR

Running Sorcery primary with Precision secondary allows Anivia to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.


Anivia matchup data for League of Legends patch 26.7. The table below shows Anivia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Anivia build, runes, laning stats, and early vs late game analysis for that specific matchup.

Anivia matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
43.37%836.674612,01848.6%39.1%
38.36%736.775011,25838.7%38.1%
41.94%626.668811,23941.9%41.9%
37.74%536.380811,34037.0%38.5%
50.00%524.365710,28650.0%50.0%
44.23%526.679810,75548.1%40.0%
55.77%525.975612,17466.7%48.4%
47.83%466.684411,23252.2%43.5%
48.89%456.575211,20645.0%52.0%
54.55%446.267111,13960.9%47.6%
59.52%426.873410,49773.1%37.5%
50.00%406.869410,26242.9%57.9%
44.74%386.570410,53950.0%37.5%
31.43%356.878212,63433.3%30.4%
35.48%316.383112,71142.9%29.4%
48.39%316.870312,66940.0%56.3%
38.71%311.853810,15545.5%35.0%
54.84%314.883311,99650.0%57.1%
60.00%306.271311,45945.5%68.4%
53.33%306.975311,39762.5%42.9%
41.38%296.682811,87636.4%44.4%
50.00%286.773111,81358.3%43.8%
44.44%276.665810,34743.8%45.5%
44.44%274.867810,34038.5%50.0%
53.85%266.780310,96530.8%76.9%
62.50%246.884611,82076.9%45.5%
54.17%245.274412,21557.1%52.9%
45.83%246.471311,90144.4%46.7%
47.83%231.95409,03750.0%45.5%
56.52%236.375412,08170.0%46.1%
69.57%236.875711,04371.4%66.7%
50.00%226.067311,80525.0%64.3%
59.09%226.873611,46853.9%66.7%
47.62%211.95419,21633.3%58.3%
60.00%206.978312,31860.0%60.0%
45.00%201.94849,49440.0%50.0%
45.00%206.280010,89833.3%54.5%
36.84%191.95597,75246.1%16.7%
52.63%193.664510,67575.0%36.4%
31.58%192.85448,37428.6%40.0%
21.05%191.85629,76025.0%18.2%
57.89%196.787411,13055.6%60.0%
68.42%196.678812,01471.4%66.7%
33.33%187.183912,36150.0%25.0%
55.56%183.664611,34933.3%66.7%
35.29%172.463310,03922.2%50.0%
41.18%177.069611,07140.0%42.9%
35.29%176.571411,48428.6%40.0%
31.25%163.185610,56933.3%30.0%
50.00%162.75339,91240.0%54.5%
50.00%163.55749,07512.5%87.5%
60.00%151.960210,52733.3%77.8%
46.67%155.367213,05360.0%40.0%
42.86%141.75328,24640.0%50.0%
57.14%141.74578,91950.0%62.5%
64.29%141.75269,39766.7%62.5%
38.46%136.583212,10816.7%57.1%
61.54%136.879213,00366.7%57.1%
61.54%136.371710,46862.5%60.0%
69.23%136.885612,70283.3%57.1%
76.92%137.279812,363100.0%50.0%
41.67%125.792412,47950.0%37.5%
41.67%121.94858,55237.5%50.0%
83.33%127.31,15912,87880.0%85.7%
58.33%125.568212,22440.0%71.4%
63.64%116.890710,27380.0%50.0%
63.64%116.01,06210,87680.0%50.0%
27.27%111.55528,62725.0%33.3%
36.36%114.991914,95825.0%42.9%
45.45%116.492711,56450.0%40.0%
27.27%111.760810,16950.0%22.2%
40.00%106.490812,21640.0%40.0%
60.00%107.677212,32275.0%50.0%
70.00%106.385311,39360.0%80.0%
77.78%96.81,03913,830100.0%75.0%
22.22%92.84618,7840.0%40.0%
44.44%96.978211,81150.0%42.9%
44.44%92.957312,3380.0%50.0%
22.22%96.366911,0900.0%33.3%
44.44%96.387812,55350.0%40.0%
55.56%91.661111,01066.7%50.0%
62.50%86.764912,597100.0%57.1%
50.00%82.566810,737100.0%42.9%
62.50%86.778511,94633.3%80.0%
37.50%87.477111,91666.7%20.0%
87.50%87.61,01513,365100.0%75.0%
57.14%77.06549,67540.0%100.0%
71.43%77.997312,83380.0%50.0%
71.43%76.469410,66375.0%66.7%
42.86%77.06589,61460.0%0.0%
14.29%77.185411,6170.0%25.0%
50.00%66.08157,92350.0%50.0%
66.67%67.079214,190100.0%60.0%
83.33%66.295112,293100.0%75.0%
50.00%66.25959,45050.0%50.0%
50.00%63.575212,7410.0%50.0%
66.67%66.152511,39850.0%75.0%
16.67%61.94419,1820.0%25.0%
40.00%57.277811,38733.3%50.0%
80.00%57.266811,841100.0%66.7%
20.00%51.66978,61820.0%0.0%
60.00%56.998513,7750.0%75.0%
20.00%53.15079,3830.0%33.3%

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Anivia vs Vayne - Frequently Asked Questions

How does Anivia do against Vayne in League of Legends?

Anivia wins the Anivia vs Vayne matchup with a 80.0% win rate compared to Vayne's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.

How does Anivia do against Vayne in the early game?

In the early game, Anivia has the advantage against Vayne with a 100.0% win rate versus 0.0%. Anivia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Anivia do against Vayne in the late game?

In the late game, Anivia takes over the Anivia vs Vayne matchup with a 66.7% win rate compared to 33.3%. Anivia scales better into team fights and objective contests after 25 minutes.

Who wins the Anivia vs Vayne matchup?

Anivia wins the matchup against Vayne with a 80.0% win rate in League of Legends patch 26.7. The 60.0 percentage point advantage means Anivia is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Anivia build against Vayne?

The best Anivia build against Vayne includes Rod of Ages, Liandry's Torment, Void Staff with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Anivia runes against Vayne?

The best Anivia runes against Vayne use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Anivia vs Vayne matchup. See the full rune breakdown in the matchup comparison above.

Does Anivia counter Vayne?

Yes, Anivia has a favorable matchup against Vayne with a 80.0% win rate. Anivia strongly counters Vayne in lane based on current patch 26.7 data.

How do I play Anivia against Vayne?

When playing Anivia against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.