Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
4.9%

Vaynevs Anivia

BMarksmanAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Vayne vs Anivia is a decisive matchup in LoL patch 26.11. Vayne wins with a 60.0% win rate (+20.0%) over Anivia based on 10 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Anivia matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 60.0% win rate in this matchup
Vayne
60.0% WR
VS
Anivia vs Vayne matchup - 40.0% win rate
Anivia
40.0% WR

Who Wins the Vayne vs Anivia Matchup?

Vayne wins the Vayne vs Anivia matchup
Winner
Vayne
Matches: 10
60.0%
Win Rate
40.0%
5.7
CS / min
6.8
820
DMG / min
729
12,597
Gold / game
12,283
223
Heal / min
225
623
DMG Mitigated / min
814
0.4
CC / min
1.6
50.0%
Early Game WR
50.0%
62.5%
Late Game WR
37.5%

Vayne vs Anivia Matchup Summary

The Vayne vs Anivia matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Vayne wins with a 60.0% win rate compared to Anivia's 40.0%, giving Vayne a 20.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Anivia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Anivia leads by 1.3s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Anivia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Anivia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Anivia Laning Phase Breakdown

Anivia wins the laning phase against Vayne in League of Legends

Anivia is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Anivia holds advantages in farming, crowd control and sustain, making them the stronger laner in this matchup.

Farming
5.7Vayne
6.8Anivia
Anivia significantly out-farms Vayne by 1.0 CS per minute, accumulating an estimated 16 CS lead by mid game. This substantial farming gap gives Anivia a major gold advantage and earlier item completions. Vayne players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
820Vayne
729Anivia
Vayne heavily out-damages Anivia by 91 DMG/min, dominating both short trades and all-in fights. Anivia should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,597Vayne
12,283Anivia
Vayne earns 314 more gold per game than Anivia, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Vayne slightly faster item completions.
Utility
0.4Vayne
1.6Anivia
Anivia brings significantly more crowd control than Vayne, with 1.3 more seconds of CC per minute. This large utility gap makes Anivia far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Vayne should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
845Vayne
1,040Anivia
Anivia vastly out-sustains Vayne, healing and mitigating 194 more damage per minute. This massive durability gap means Anivia can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Anivia

Boots of Swiftness is the optimal boots choice against Anivia, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Anivia are Immortal Shieldbow, Edge of Night and Mercurial Scimitar. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Anivia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Anivia matchup.

Early Game vs Late Game

Early Game
Vayne
50.0%
+0.0% advantage
Vayne early game win rateVayne50.0%
Anivia early game win rateAnivia50.0%
Late Game
Vayne
62.5%
+25.0% advantage
Vayne late game win rateVayne62.5%
Anivia late game win rateAnivia37.5%

The early game (first 15 minutes) is a toss-up between Vayne and Anivia, with Vayne holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vayne is far superior in the late game (25+ minutes), boasting a 62.5% win rate — 25.0 points above Anivia. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Anivia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Anivia

Precision rune tree - Vayne primary runes vs AniviaPrecision
Press the Attack - best Vayne rune vs AniviaTriumph - best Vayne rune vs AniviaLegend: Alacrity - best Vayne rune vs AniviaCoup de Grace - best Vayne rune vs Anivia
Resolve rune tree - Vayne secondary runes vs AniviaResolve
Bone Plating - best Vayne rune vs AniviaOvergrowth - best Vayne rune vs Anivia
100.0% WR

Running Precision primary with Resolve secondary allows Vayne to press their advantage against Anivia, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.11. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
46.01%4766.078912,87544.3%47.4%
47.20%4476.079112,72545.4%48.6%
46.26%4285.779612,71544.9%47.3%
53.92%3956.085712,96853.2%54.6%
47.85%3726.289413,18946.8%48.6%
52.99%3516.284313,14252.5%53.4%
52.98%2856.390413,45646.2%58.8%
53.90%2696.387713,73748.2%58.0%
52.38%1895.988612,46846.1%58.2%
51.92%1566.591311,98950.0%53.4%
54.30%1516.185913,22758.5%51.2%
50.33%1516.180413,00743.8%55.2%
45.95%1485.978013,60345.3%46.3%
45.38%1306.177613,08138.2%50.7%
47.83%1156.481213,76538.5%52.6%
42.61%1156.178112,08234.0%49.2%
50.88%1145.886612,98941.2%58.7%
45.19%1046.489913,17548.7%43.1%
59.80%1026.585413,18963.5%56.0%
31.00%1005.563510,36011.1%47.3%
45.83%965.885713,16444.4%46.7%
50.53%956.31,12012,73751.6%50.0%
58.06%936.379613,00854.8%60.8%
44.09%935.862511,33042.4%45.0%
45.56%905.883011,35543.6%47.1%
45.98%876.385113,57237.9%50.0%
55.81%866.189910,74843.2%65.3%
55.95%846.21,29211,54651.4%59.2%
56.41%786.388313,43557.1%55.8%
54.84%625.981412,06158.3%52.6%
45.76%596.287712,77548.0%44.1%
51.92%526.091311,59248.1%56.0%
45.10%516.592112,14440.9%48.3%
52.00%506.087513,62147.8%55.6%
35.42%486.272110,98228.0%43.5%
58.33%486.198911,81064.0%52.2%
45.83%486.21,00510,83851.9%38.1%
50.00%466.297013,36447.4%51.9%
58.70%466.291413,67162.5%54.5%
54.55%446.287414,06357.1%53.3%
44.19%436.683913,74455.0%34.8%
26.19%425.987411,67823.5%28.0%
48.78%415.983611,64443.5%55.6%
52.50%405.683813,60737.5%56.3%
38.46%396.785410,96150.0%28.6%
41.03%396.07439,57128.6%55.6%
67.57%376.589811,52662.5%76.9%
45.95%375.683211,99840.0%50.0%
52.94%346.475912,24550.0%54.5%
52.94%346.41,05111,47452.6%53.3%
66.67%336.393813,52461.5%70.0%
48.48%336.478411,26950.0%46.1%
48.48%336.597913,30562.5%44.0%
40.63%325.382011,34442.1%38.5%
62.50%325.779613,16341.7%75.0%
40.63%326.267610,36931.6%53.9%
58.06%316.484912,13864.3%52.9%
53.33%305.685512,15255.6%52.4%
60.00%306.095312,30876.9%47.1%
43.33%306.664611,44137.5%50.0%
55.56%275.379211,00650.0%60.0%
48.15%276.283411,46543.8%54.5%
50.00%265.969311,80141.7%57.1%
50.00%266.171011,42146.1%53.9%
30.77%265.370011,00127.3%33.3%
50.00%265.883412,30154.5%46.7%
48.00%256.081612,91020.0%66.7%
44.00%256.475811,84450.0%38.5%
54.17%246.399112,32564.3%40.0%
45.83%246.085011,12557.1%30.0%
56.52%235.761010,29945.5%66.7%
45.45%226.573412,18438.5%55.6%
40.91%226.080612,81544.4%38.5%
42.11%196.292010,37245.5%37.5%
63.16%196.387012,58950.0%72.7%
42.11%195.881712,14257.1%33.3%
61.11%185.61,00813,43366.7%58.3%
62.50%166.188511,54762.5%62.5%
80.00%152.288517,36850.0%84.6%
53.33%156.498513,30150.0%54.5%
60.00%156.583311,24437.5%85.7%
46.67%156.687611,53050.0%42.9%
46.67%155.491613,99225.0%54.5%
42.86%146.482413,96675.0%30.0%
42.86%146.084113,4470.0%66.7%
53.85%136.584913,506100.0%33.3%
46.15%135.275011,57950.0%42.9%
66.67%125.61,02512,92880.0%57.1%
33.33%126.092711,90033.3%33.3%
54.55%115.61,00213,29850.0%57.1%
63.64%116.164210,20450.0%80.0%
54.55%112.982014,06866.7%40.0%
81.82%116.277512,783100.0%71.4%
54.55%113.484613,74333.3%62.5%
54.55%115.576111,64971.4%25.0%
45.45%115.69159,80875.0%28.6%
40.00%104.670811,73250.0%25.0%
60.00%105.782012,59750.0%62.5%
50.00%103.877113,23733.3%57.1%
40.00%105.592611,89340.0%40.0%
66.67%93.81,03913,79866.7%66.7%
33.33%96.11,07613,2730.0%50.0%
55.56%96.793013,145100.0%20.0%
33.33%96.085513,01833.3%33.3%
55.56%93.986012,86033.3%66.7%
50.00%85.887014,56550.0%50.0%
62.50%87.368411,84766.7%50.0%
50.00%83.288313,47975.0%25.0%
25.00%85.26909,10216.7%50.0%
37.50%85.85269,89450.0%25.0%
57.14%74.076010,75033.3%75.0%
71.43%73.674311,42580.0%50.0%
42.86%74.572311,69733.3%50.0%
28.57%74.567612,0460.0%40.0%
50.00%63.578115,0220.0%60.0%
33.33%66.882313,7790.0%50.0%
33.33%62.998912,89833.3%33.3%
66.67%65.91,00614,14350.0%75.0%
20.00%54.75778,99933.3%0.0%
40.00%52.161112,29050.0%0.0%
40.00%56.41,17614,5940.0%50.0%
80.00%56.21,02413,762100.0%66.7%
40.00%55.996213,2480.0%50.0%
40.00%56.06739,21850.0%0.0%
40.00%56.47269,89240.0%0.0%

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Vayne vs Anivia - Frequently Asked Questions

How does Vayne do against Anivia in League of Legends?

Vayne wins the Vayne vs Anivia matchup with a 60.0% win rate compared to Anivia's 40.0%, a 20.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.11.

How does Vayne do against Anivia in the early game?

In the early game, Vayne has the advantage against Anivia with a 50.0% win rate versus 50.0%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Anivia in the late game?

In the late game, Vayne takes over the Vayne vs Anivia matchup with a 62.5% win rate compared to 37.5%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Anivia matchup?

Vayne wins the matchup against Anivia with a 60.0% win rate in League of Legends patch 26.11. The 20.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Vayne build against Anivia?

The best Vayne build against Anivia includes Immortal Shieldbow, Edge of Night, Mercurial Scimitar with Boots of Swiftness. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Anivia?

The best Vayne runes against Anivia use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Anivia matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Anivia?

Yes, Vayne has a favorable matchup against Anivia with a 60.0% win rate. Vayne strongly counters Anivia in lane based on current patch 26.11 data.

How do I play Vayne against Anivia?

When playing Vayne against Anivia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.