Cassiopeiavs Vayne
Cassiopeia vs Vayne is a decisive matchup in LoL patch 26.7. Cassiopeia wins with a 60.0% win rate (+20.0%) over Vayne based on 5 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Vayne matchup.
Cassiopeia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Vayne(60.0%)Who Wins the Cassiopeia vs Vayne Matchup?
Cassiopeia vs Vayne Matchup Summary
The Cassiopeia vs Vayne matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Cassiopeia wins with a 60.0% win rate compared to Vayne's 40.0%, giving Cassiopeia a 20.0 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Cassiopeia leads by 1.4s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Vayne and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Vayne away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Cassiopeia vs Vayne Laning Phase Breakdown
Cassiopeia is favored during the laning phase against Vayne, winning 3 out of 5 key stat categories. Cassiopeia holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.
Best Cassiopeia Build Against Vayne
Sorcerer's Shoes is the optimal boots choice against Vayne, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Vayne are Shadowflame, Cosmic Drive and Rylai's Crystal Scepter. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Vayne. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Vayne matchup.
Early Game vs Late Game
Cassiopeia0.0%Vayne0.0%Cassiopeia60.0%Vayne40.0%The early game (first 15 minutes) is a toss-up between Cassiopeia and Vayne, with Cassiopeia holding a razor-thin 0.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.
Cassiopeia is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Vayne. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.
Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Cassiopeia Runes Against Vayne
Precision
Sorcery
Running Precision primary with Sorcery secondary allows Cassiopeia to press their advantage against Vayne, amplifying the strengths that make this a favorable matchup.
Cassiopeia matchup data for League of Legends patch 26.7. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 56.25% | 32 | 6.7 | 885 | 12,088 | 50.0% | 66.7% | |
| 55.17% | 29 | 7.0 | 829 | 11,663 | 50.0% | 60.0% | |
| 48.00% | 25 | 6.7 | 767 | 12,316 | 50.0% | 47.4% | |
| 47.83% | 23 | 6.8 | 729 | 11,512 | 40.0% | 62.5% | |
| 45.45% | 22 | 6.3 | 859 | 13,061 | 20.0% | 52.9% | |
| 59.09% | 22 | 6.4 | 849 | 12,548 | 62.5% | 57.1% | |
| 42.11% | 19 | 6.9 | 864 | 11,121 | 27.3% | 62.5% | |
| 42.11% | 19 | 6.5 | 908 | 10,894 | 33.3% | 57.1% | |
| 57.89% | 19 | 6.4 | 921 | 12,992 | 28.6% | 75.0% | |
| 41.18% | 17 | 6.3 | 739 | 12,065 | 37.5% | 44.4% | |
| 35.29% | 17 | 6.7 | 736 | 11,498 | 14.3% | 50.0% | |
| 58.82% | 17 | 7.0 | 761 | 10,089 | 61.5% | 50.0% | |
| 43.75% | 16 | 6.5 | 793 | 12,564 | 33.3% | 46.1% | |
| 37.50% | 16 | 6.6 | 799 | 11,966 | 33.3% | 40.0% | |
| 37.50% | 16 | 6.7 | 692 | 11,337 | 28.6% | 44.4% | |
| 66.67% | 15 | 6.1 | 948 | 12,981 | 75.0% | 63.6% | |
| 66.67% | 15 | 7.0 | 980 | 13,675 | 100.0% | 54.5% | |
| 50.00% | 14 | 6.5 | 804 | 11,933 | 33.3% | 62.5% | |
| 57.14% | 14 | 6.5 | 650 | 11,062 | 50.0% | 62.5% | |
| 21.43% | 14 | 6.4 | 858 | 12,885 | 66.7% | 9.1% | |
| 46.15% | 13 | 6.8 | 691 | 9,869 | 37.5% | 60.0% | |
| 69.23% | 13 | 6.4 | 940 | 11,618 | 66.7% | 71.4% | |
| 58.33% | 12 | 6.9 | 840 | 13,601 | 50.0% | 66.7% | |
| 66.67% | 12 | 6.9 | 1,017 | 11,759 | 50.0% | 83.3% | |
| 36.36% | 11 | 6.2 | 623 | 11,142 | 60.0% | 16.7% | |
| 81.82% | 11 | 6.8 | 942 | 11,319 | 71.4% | 100.0% | |
| 54.55% | 11 | 6.5 | 930 | 13,223 | 60.0% | 50.0% | |
| 63.64% | 11 | 7.4 | 659 | 9,845 | 55.6% | 100.0% | |
| 36.36% | 11 | 5.5 | 830 | 12,700 | 25.0% | 42.9% | |
| 45.45% | 11 | 6.7 | 1,090 | 12,212 | 25.0% | 57.1% | |
| 45.45% | 11 | 7.1 | 790 | 11,958 | 50.0% | 42.9% | |
| 40.00% | 10 | 6.4 | 836 | 13,983 | 33.3% | 42.9% | |
| 20.00% | 10 | 7.5 | 658 | 11,942 | 0.0% | 25.0% | |
| 77.78% | 9 | 7.0 | 930 | 11,929 | 100.0% | 60.0% | |
| 44.44% | 9 | 6.1 | 1,062 | 14,147 | 100.0% | 37.5% | |
| 33.33% | 9 | 6.3 | 740 | 10,388 | 20.0% | 50.0% | |
| 62.50% | 8 | 6.2 | 932 | 12,070 | 75.0% | 50.0% | |
| 50.00% | 8 | 6.5 | 840 | 11,206 | 60.0% | 33.3% | |
| 62.50% | 8 | 7.2 | 1,069 | 13,954 | 50.0% | 66.7% | |
| 37.50% | 8 | 7.3 | 753 | 11,987 | 0.0% | 60.0% | |
| 62.50% | 8 | 6.5 | 804 | 12,100 | 40.0% | 100.0% | |
| 71.43% | 7 | 6.7 | 1,077 | 12,316 | 50.0% | 80.0% | |
| 42.86% | 7 | 6.6 | 1,025 | 13,529 | 50.0% | 40.0% | |
| 57.14% | 7 | 6.2 | 825 | 11,090 | 66.7% | 50.0% | |
| 28.57% | 7 | 6.4 | 793 | 13,236 | 50.0% | 0.0% | |
| 85.71% | 7 | 7.0 | 970 | 12,450 | 100.0% | 75.0% | |
| 83.33% | 6 | 6.8 | 641 | 10,210 | 75.0% | 100.0% | |
| 33.33% | 6 | 6.5 | 752 | 10,289 | 25.0% | 50.0% | |
| 83.33% | 6 | 6.7 | 840 | 13,445 | 50.0% | 100.0% | |
| 33.33% | 6 | 6.8 | 758 | 10,811 | 25.0% | 50.0% | |
| 66.67% | 6 | 5.9 | 872 | 14,875 | 100.0% | 60.0% | |
| 16.67% | 6 | 6.1 | 558 | 10,776 | 0.0% | 50.0% | |
| 83.33% | 6 | 6.9 | 862 | 13,632 | 100.0% | 50.0% | |
| 60.00% | 5 | 7.1 | 905 | 15,491 | 0.0% | 75.0% | |
| 0.00% | 5 | 6.9 | 1,073 | 12,453 | 0.0% | 0.0% | |
| 60.00% | 5 | 7.3 | 1,077 | 13,114 | 66.7% | 50.0% | |
| 80.00% | 5 | 6.9 | 999 | 12,801 | 100.0% | 50.0% | |
| 40.00% | 5 | 6.7 | 834 | 10,909 | 33.3% | 50.0% | |
| 20.00% | 5 | 5.7 | 754 | 9,531 | 33.3% | 0.0% | |
| 80.00% | 5 | 7.0 | 796 | 11,092 | 75.0% | 100.0% | |
| 40.00% | 5 | 6.7 | 745 | 13,361 | 100.0% | 0.0% | |
| 80.00% | 5 | 7.2 | 675 | 8,508 | 100.0% | 50.0% | |
| 60.00% | 5 | 5.9 | 1,144 | 16,919 | 0.0% | 60.0% | |
| 60.00% | 5 | 6.7 | 732 | 9,347 | 100.0% | 0.0% | |
| 20.00% | 5 | 6.8 | 954 | 11,166 | 33.3% | 0.0% | |
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Cassiopeia vs Vayne - Frequently Asked Questions
How does Cassiopeia do against Vayne in League of Legends?
Cassiopeia wins the Cassiopeia vs Vayne matchup with a 60.0% win rate compared to Vayne's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.7.
How does Cassiopeia do against Vayne in the early game?
In the early game, Cassiopeia has the advantage against Vayne with a 0.0% win rate versus 0.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Cassiopeia do against Vayne in the late game?
In the late game, Cassiopeia takes over the Cassiopeia vs Vayne matchup with a 60.0% win rate compared to 40.0%. Cassiopeia scales better into team fights and objective contests after 25 minutes.
Who wins the Cassiopeia vs Vayne matchup?
Cassiopeia wins the matchup against Vayne with a 60.0% win rate in League of Legends patch 26.7. The 20.0 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 5 games analyzed.
What is the best Cassiopeia build against Vayne?
The best Cassiopeia build against Vayne includes Shadowflame, Cosmic Drive, Rylai's Crystal Scepter with Sorcerer's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Cassiopeia runes against Vayne?
The best Cassiopeia runes against Vayne use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Vayne matchup. See the full rune breakdown in the matchup comparison above.
Does Cassiopeia counter Vayne?
Yes, Cassiopeia has a favorable matchup against Vayne with a 60.0% win rate. Cassiopeia strongly counters Vayne in lane based on current patch 26.7 data.
How do I play Cassiopeia against Vayne?
When playing Cassiopeia against Vayne, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.