Karthus - League of Legends Champion
Win Rate
50.1%
Pick Rate
1.2%

Karthusvs Nautilus

BMage
Patch26.10
Matches1,492,117
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 20, 2026
MethodologyData Methodology

Karthus vs Nautilus is a decisive matchup in LoL patch 26.10. Nautilus wins with a 80.0% win rate (+60.0%) over Karthus based on 5 games. Karthus wins the early laning phase while Nautilus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Nautilus matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Nautilus - 20.0% win rateNautilus(20.0%)
Karthus - 20.0% win rate in this matchup
Karthus
20.0% WR
VS
Nautilus vs Karthus matchup - 80.0% win rate
Nautilus
80.0% WR

Who Wins the Karthus vs Nautilus Matchup?

Nautilus wins the Karthus vs Nautilus matchup
Winner
Nautilus
Matches: 5
20.0%
Win Rate
80.0%
2.3
CS / min
1.3
1,122
DMG / min
529
13,874
Gold / game
12,208
136
Heal / min
186
469
DMG Mitigated / min
1,983
0.8
CC / min
2.4
100.0%
Early Game WR
0.0%
0.0%
Late Game WR
100.0%

Karthus vs Nautilus Matchup Summary

The Karthus vs Nautilus matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Nautilus wins with a 80.0% win rate compared to Karthus's 20.0%, giving Nautilus a 60.0 percentage point advantage. Game phase dynamics play a critical role here: Karthus controls the early laning stage, but Nautilus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Karthus needs to press advantages before Nautilus reaches their power spikes, while Nautilus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Nautilus leads by 1,564 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Nautilus has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Nautilus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Nautilus Laning Phase Breakdown

Karthus wins the laning phase against Nautilus in League of Legends

Karthus is favored during the laning phase against Nautilus, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
2.3Karthus
1.3Nautilus
Karthus significantly out-farms Nautilus by 1.1 CS per minute, accumulating an estimated 16 CS lead by mid game. This substantial farming gap gives Karthus a major gold advantage and earlier item completions. Nautilus players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
1,122Karthus
529Nautilus
Karthus heavily out-damages Nautilus by 593 DMG/min, dominating both short trades and all-in fights. Nautilus should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,874Karthus
12,208Nautilus
Karthus generates a commanding 1,666 more gold per game than Nautilus. This substantial economic advantage means Karthus consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Nautilus should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.8Karthus
2.4Nautilus
Nautilus brings significantly more crowd control than Karthus, with 1.6 more seconds of CC per minute. This large utility gap makes Nautilus far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Karthus should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
604Karthus
2,168Nautilus
Nautilus vastly out-sustains Karthus, healing and mitigating 1,564 more damage per minute. This massive durability gap means Nautilus can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Nautilus

Sorcerer's Shoes is the optimal boots choice against Nautilus, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Nautilus are Shadowflame, Zhonya's Hourglass and Malignance. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Nautilus matchup.

Early Game vs Late Game

Early Game
Karthus
100.0%
+100.0% advantage
Karthus early game win rateKarthus100.0%
Nautilus early game win rateNautilus0.0%
Late Game
Nautilus
100.0%
+100.0% advantage
Karthus late game win rateKarthus0.0%
Nautilus late game win rateNautilus100.0%

Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Nautilus. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Nautilus is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Karthus. Extended games heavily favor Nautilus, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Karthus must aggressively press their early advantage and close out the game before Nautilus reaches their scaling breakpoints. If Nautilus survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Karthus Runes Against Nautilus

Sorcery rune tree - Karthus primary runes vs NautilusSorcery
Deathfire Touch - best Karthus rune vs NautilusAxiom Arcanist - best Karthus rune vs NautilusTranscendence - best Karthus rune vs NautilusScorch - best Karthus rune vs Nautilus
Precision rune tree - Karthus secondary runes vs NautilusPrecision
Presence of Mind - best Karthus rune vs NautilusLast Stand - best Karthus rune vs Nautilus
100.0% WR

The Sorcery and Precision rune setup gives Karthus the best tools to compete against Nautilus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.10. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.72%876.51,43615,47744.4%55.0%
38.81%671.31,12513,16139.4%38.2%
56.25%641.31,19413,04853.6%58.3%
47.54%616.51,31513,77460.9%39.5%
49.12%571.31,22613,24150.0%48.1%
48.21%566.41,33314,54271.4%34.3%
49.06%531.61,25814,67943.8%51.4%
55.77%521.41,24614,31768.2%46.7%
45.83%486.41,31013,50359.1%34.6%
51.06%471.61,19014,27650.0%51.7%
47.83%466.61,29814,16350.0%46.4%
64.44%451.51,10713,99162.5%65.5%
38.64%446.81,26513,47840.0%37.5%
47.62%421.41,05612,78643.5%52.6%
47.62%421.21,14712,99544.4%50.0%
51.22%416.41,47315,65130.0%58.1%
45.00%401.41,09414,12441.7%46.4%
72.73%331.31,17112,66290.0%46.1%
60.61%331.61,25315,41075.0%56.0%
57.58%336.51,46816,29470.0%52.2%
46.88%326.31,18014,08654.5%42.9%
46.88%321.51,17813,60046.1%47.4%
51.61%311.51,20214,79846.1%55.6%
41.94%311.61,28414,23630.8%50.0%
58.62%292.01,18514,59654.5%61.1%
37.93%294.91,28913,75540.0%36.8%
51.85%271.21,17213,62150.0%53.3%
33.33%276.31,23015,01728.6%35.0%
51.85%271.51,16813,01436.4%62.5%
60.00%251.41,07412,26860.0%60.0%
56.00%251.21,23414,42140.0%66.7%
33.33%241.21,09511,94633.3%33.3%
43.48%231.81,10011,23244.4%42.9%
39.13%231.41,23813,90250.0%30.8%
50.00%222.01,14814,38725.0%55.6%
59.09%221.51,29414,98042.9%66.7%
40.91%222.11,14013,17857.1%33.3%
47.62%215.31,18714,06150.0%47.4%
57.14%211.51,23914,30633.3%66.7%
70.00%202.51,09412,70890.0%50.0%
36.84%196.01,53514,06266.7%23.1%
26.32%196.21,11210,98511.1%40.0%
52.63%196.71,24912,88355.6%50.0%
47.37%196.71,18112,60988.9%10.0%
63.16%191.51,19914,17375.0%54.5%
78.95%193.11,26815,94160.0%85.7%
33.33%186.21,24313,99557.1%18.2%
50.00%182.21,43716,30575.0%42.9%
41.18%175.01,43416,07250.0%38.5%
58.82%171.31,24914,72871.4%50.0%
58.82%176.01,22814,48733.3%64.3%
64.71%176.31,26112,77671.4%60.0%
52.94%174.31,24414,93866.7%50.0%
47.06%172.194013,06150.0%44.4%
31.25%162.21,22713,87050.0%25.0%
53.33%156.11,30014,18950.0%55.6%
46.67%151.71,36313,81540.0%50.0%
46.67%151.699413,75966.7%33.3%
46.67%153.11,21514,57471.4%25.0%
40.00%151.41,10812,71340.0%40.0%
28.57%143.993710,91225.0%30.0%
42.86%146.51,25415,88325.0%50.0%
42.86%145.81,34513,50460.0%33.3%
21.43%141.41,04411,32212.5%33.3%
50.00%146.91,23014,77125.0%60.0%
35.71%146.71,13512,15022.2%60.0%
61.54%132.81,31812,08950.0%71.4%
76.92%136.71,32415,23850.0%81.8%
66.67%126.01,36315,16666.7%66.7%
58.33%122.392511,28157.1%60.0%
27.27%113.21,33314,15350.0%14.3%
45.45%116.51,13412,11060.0%33.3%
54.55%114.690911,36866.7%40.0%
36.36%113.61,24512,58133.3%37.5%
30.00%103.61,13714,21633.3%28.6%
30.00%104.71,38812,64225.0%33.3%
60.00%106.11,55313,14466.7%50.0%
60.00%101.71,15412,30560.0%60.0%
44.44%91.41,24815,30225.0%60.0%
66.67%95.81,10412,813100.0%57.1%
77.78%96.81,29912,37350.0%85.7%
66.67%91.31,04812,239100.0%40.0%
87.50%84.51,19713,451100.0%80.0%
25.00%83.41,14213,50933.3%20.0%
87.50%86.41,47414,41275.0%100.0%
62.50%87.01,11710,44575.0%50.0%
28.57%74.01,33913,9550.0%40.0%
42.86%71.61,09211,84950.0%33.3%
71.43%76.91,32613,79050.0%100.0%
42.86%76.51,29313,07950.0%33.3%
42.86%75.41,43910,76333.3%50.0%
14.29%72.61,55313,9700.0%20.0%
71.43%76.41,14711,13566.7%100.0%
28.57%73.11,17012,82120.0%50.0%
28.57%76.51,42014,40550.0%20.0%
50.00%65.11,11810,97925.0%100.0%
83.33%66.41,24814,492100.0%75.0%
50.00%64.98565,88340.0%100.0%
50.00%65.97556,75750.0%50.0%
16.67%62.71,32815,1970.0%20.0%
83.33%61.51,33912,763100.0%66.7%
33.33%61.81,19810,54240.0%0.0%
20.00%52.31,12213,874100.0%0.0%
60.00%52.280511,041100.0%50.0%
80.00%56.91,83313,03550.0%100.0%
60.00%56.41,52016,893100.0%50.0%
40.00%57.01,05313,5150.0%50.0%
60.00%54.71,49115,869100.0%50.0%
80.00%57.01,31014,701100.0%75.0%
60.00%56.61,02913,18933.3%100.0%
40.00%57.21,22312,39825.0%100.0%
20.00%56.71,2529,7390.0%33.3%
20.00%56.81,04914,3630.0%20.0%

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Karthus vs Nautilus - Frequently Asked Questions

How does Karthus do against Nautilus in League of Legends?

Nautilus wins the Karthus vs Nautilus matchup with a 80.0% win rate compared to Karthus's 20.0%, a 60.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Karthus do against Nautilus in the early game?

In the early game, Karthus has the advantage against Nautilus with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Nautilus in the late game?

In the late game, Nautilus takes over the Karthus vs Nautilus matchup with a 100.0% win rate compared to 0.0%. Nautilus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Nautilus matchup?

Nautilus wins the matchup against Karthus with a 80.0% win rate in League of Legends patch 26.10. The 60.0 percentage point advantage means Nautilus is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karthus build against Nautilus?

The best Karthus build against Nautilus includes Shadowflame, Zhonya's Hourglass, Malignance with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Nautilus?

The best Karthus runes against Nautilus use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Nautilus matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Nautilus?

No, Karthus struggles against Nautilus with only a 20.0% win rate. Nautilus has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Nautilus's lead.

How do I play Karthus against Nautilus?

When playing Karthus against Nautilus, play cautiously and avoid Nautilus's power spikes. Look for jungle assistance and team-dependent plays since Nautilus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.