Lissandra - League of Legends Champion
Win Rate
51.3%
Pick Rate
1.9%

Lissandravs Zyra

AMage
Patch26.10
Matches788,689
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 18, 2026
MethodologyData Methodology

Lissandra vs Zyra is a decisive matchup in LoL patch 26.10. Zyra wins with a 60.0% win rate (+20.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Zyra scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Zyra matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zyra - 40.0% win rateZyra(40.0%)
Lissandra - 40.0% win rate in this matchup
Lissandra
40.0% WR
VS
Zyra vs Lissandra matchup - 60.0% win rate
Zyra
60.0% WR

Who Wins the Lissandra vs Zyra Matchup?

Zyra wins the Lissandra vs Zyra matchup
Winner
Zyra
Matches: 5
40.0%
Win Rate
60.0%
4.3
CS / min
4.0
675
DMG / min
995
11,128
Gold / game
10,656
134
Heal / min
83
315
DMG Mitigated / min
302
1.7
CC / min
2.1
50.0%
Early Game WR
50.0%
33.3%
Late Game WR
66.7%

Lissandra vs Zyra Matchup Summary

The Lissandra vs Zyra matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Zyra wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Zyra a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Zyra outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Zyra reaches their power spikes, while Zyra should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in damage output, where Zyra leads by 320 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Zyra has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Zyra overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Zyra Laning Phase Breakdown

Lissandra wins the laning phase against Zyra in League of Legends

Lissandra is favored during the laning phase against Zyra, winning 3 out of 5 key stat categories. Lissandra holds advantages in farming, gold income and sustain, making them the stronger laner in this matchup.

Farming
4.3Lissandra
4.0Zyra
Lissandra and Zyra farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
675Lissandra
995Zyra
Zyra heavily out-damages Lissandra by 320 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zyra's sustained damage advantage take over.
Economy
11,128Lissandra
10,656Zyra
Lissandra earns 472 more gold per game than Zyra, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Lissandra slightly faster item completions.
Utility
1.7Lissandra
2.1Zyra
Zyra provides 0.4 seconds more crowd control per minute than Lissandra, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Zyra coordinate with their jungler and control the pace of skirmishes.
Sustain
449Lissandra
385Zyra
Lissandra heals and mitigates 64 more damage per minute than Zyra, providing moderate extra durability. This sustain edge allows Lissandra to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Zyra.

Best Lissandra Build Against Zyra

Ionian Boots of Lucidity is the optimal boots choice against Zyra, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Zyra are Morellonomicon, Rylai's Crystal Scepter and Blackfire Torch. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Zyra matchup.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Zyra early game win rateZyra50.0%
Late Game
Zyra
66.7%
+33.3% advantage
Lissandra late game win rateLissandra33.3%
Zyra late game win rateZyra66.7%

The early game (first 15 minutes) is a toss-up between Lissandra and Zyra, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Zyra is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Lissandra. Extended games heavily favor Zyra, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Lissandra has the edge early, but Zyra gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Lissandra Runes Against Zyra

Sorcery rune tree - Lissandra primary runes vs ZyraSorcery
Arcane Comet - best Lissandra rune vs ZyraManaflow Band - best Lissandra rune vs ZyraTranscendence - best Lissandra rune vs ZyraGathering Storm - best Lissandra rune vs Zyra
Precision rune tree - Lissandra secondary runes vs ZyraPrecision
Triumph - best Lissandra rune vs ZyraCut Down - best Lissandra rune vs Zyra
100.0% WR

The Sorcery and Precision rune setup gives Lissandra the best tools to compete against Zyra in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.10. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.05%1716.676911,31151.3%52.8%
56.96%1586.883812,10962.9%53.1%
56.25%1446.880212,07560.0%53.9%
57.35%1366.585111,77743.3%68.4%
54.17%1206.689411,83858.7%51.4%
52.10%1196.675911,54458.0%47.8%
50.55%916.886411,83342.9%55.4%
50.00%866.076311,36348.6%51.0%
49.40%836.668210,75635.1%60.9%
53.09%816.894512,08459.5%47.7%
48.65%746.587012,07565.5%37.8%
44.44%726.480011,90248.0%42.5%
40.30%676.679112,26054.2%32.6%
41.07%567.091010,56442.9%39.3%
43.75%486.492611,68442.9%44.4%
45.83%486.976410,31648.1%42.9%
44.68%477.191310,27446.1%42.9%
48.89%456.774111,85055.6%44.4%
56.82%446.680710,71460.0%52.6%
47.50%406.888911,81435.7%53.9%
52.50%406.580111,07859.1%44.4%
48.72%396.379410,53757.9%40.0%
54.05%376.289411,67847.1%60.0%
48.65%376.884212,04869.2%37.5%
52.78%366.577912,44260.0%50.0%
50.00%346.67739,95460.0%42.1%
50.00%346.789912,47850.0%50.0%
59.38%326.685112,14046.1%68.4%
43.75%326.373511,21155.6%39.1%
62.50%327.089211,23666.7%58.8%
35.48%316.790111,72750.0%28.6%
33.33%305.891912,36750.0%25.0%
36.67%306.988112,31350.0%31.8%
51.72%296.881710,56962.5%38.5%
51.72%296.979211,75670.0%42.1%
53.85%266.279111,44255.6%52.9%
61.54%266.881611,31671.4%50.0%
50.00%226.884211,41060.0%41.7%
45.45%227.184710,22553.9%33.3%
61.90%215.885210,29258.3%66.7%
55.00%205.780510,44766.7%45.5%
35.00%206.567211,29344.4%27.3%
26.32%195.971112,06425.0%27.3%
41.18%176.976510,63760.0%14.3%
70.59%176.589712,69080.0%66.7%
43.75%163.559310,75350.0%41.7%
66.67%157.092911,70940.0%80.0%
53.33%156.783211,82150.0%57.1%
66.67%156.676910,95857.1%75.0%
60.00%156.888914,333100.0%50.0%
66.67%157.490412,42385.7%50.0%
42.86%143.885213,75866.7%36.4%
38.46%136.384413,80350.0%36.4%
69.23%135.977812,797100.0%60.0%
66.67%126.786011,77966.7%66.7%
41.67%126.888512,73525.0%50.0%
72.73%117.486911,82080.0%66.7%
36.36%116.399712,01833.3%40.0%
50.00%106.874311,79066.7%25.0%
22.22%91.54868,3950.0%33.3%
33.33%96.773911,320100.0%14.3%
33.33%97.577010,76266.7%16.7%
55.56%96.91,07811,74633.3%66.7%
22.22%97.082511,61320.0%25.0%
66.67%96.189612,85166.7%66.7%
22.22%95.776010,70850.0%14.3%
37.50%82.05567,33950.0%0.0%
37.50%87.594613,49166.7%20.0%
37.50%87.391710,19520.0%66.7%
50.00%82.75139,630100.0%33.3%
50.00%87.31,05311,45750.0%50.0%
25.00%86.882811,86333.3%20.0%
57.14%72.462312,2880.0%57.1%
85.71%76.499811,349100.0%75.0%
28.57%75.272210,611100.0%16.7%
71.43%77.094211,67033.3%100.0%
57.14%76.57077,45375.0%33.3%
28.57%77.01,20012,84850.0%20.0%
83.33%66.993211,04975.0%100.0%
83.33%67.61,02412,158100.0%66.7%
50.00%66.785513,791100.0%40.0%
33.33%67.094112,15450.0%25.0%
16.67%66.399410,56850.0%0.0%
33.33%66.278310,96850.0%25.0%
66.67%64.367711,77250.0%75.0%
40.00%52.05108,11966.7%0.0%
80.00%55.390610,607100.0%50.0%
40.00%54.367511,12850.0%33.3%
60.00%56.28127,81460.0%0.0%
20.00%51.85648,39950.0%0.0%
80.00%56.86467,52875.0%100.0%
60.00%57.463411,653100.0%50.0%
60.00%52.46207,49933.3%100.0%
60.00%53.77858,70650.0%66.7%
0.00%56.675011,4390.0%0.0%
60.00%55.878911,40250.0%66.7%
60.00%53.84173,79660.0%0.0%
40.00%56.37717,0390.0%100.0%

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Lissandra vs Zyra - Frequently Asked Questions

How does Lissandra do against Zyra in League of Legends?

Zyra wins the Lissandra vs Zyra matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Lissandra do against Zyra in the early game?

In the early game, Lissandra has the advantage against Zyra with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Zyra in the late game?

In the late game, Zyra takes over the Lissandra vs Zyra matchup with a 66.7% win rate compared to 33.3%. Zyra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Zyra matchup?

Zyra wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Zyra is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Zyra?

The best Lissandra build against Zyra includes Morellonomicon, Rylai's Crystal Scepter, Blackfire Torch with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Zyra?

The best Lissandra runes against Zyra use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Zyra matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Zyra?

No, Lissandra struggles against Zyra with only a 40.0% win rate. Zyra has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Zyra's lead.

How do I play Lissandra against Zyra?

When playing Lissandra against Zyra, play cautiously and avoid Zyra's power spikes. Look for jungle assistance and team-dependent plays since Zyra has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.