Zoe, League of Legends champion
Win Rate
48.1%
Pick Rate
1.4%
Ban Rate
2.2%

Zoe Mid Runes: Keystone & Shards

Zoe F TierMage
Patch
26.20
Games
2,409
Lane
Mid
Tier
All Tiers
Last Updated
Oct 16, 2026 UTC
Methodology
Data Methodology

Best Mid Zoe runes for LoL Patch 26.20 - Electrocute from the Domination tree with Sorcery secondary (67.7% WR, 1.3% pick rate). Zoe's optimal primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Secondary tree: Nimbus Cloak, Scorch.

Zoe performs best with Electrocute as the keystone rune from the Domination tree. Zoe's optimal primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Zoe's secondary rune tree is Sorcery with Nimbus Cloak, Scorch. This rune setup achieves a 67.74% win rate (+19.7% win rate difference) with a 1.3% pick rate across 31 Zoe games.
67.7%Win Rate
+19.7%WR Diff
1.3%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Taste of BloodTaste of Blood

Heal when you damage an enemy champion.

Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)

Cooldown: 20s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Nimbus CloakNimbus Cloak

After casting a Summoner Spell, gain a Move Speed increase that lasts for 2s and allows you to pass through units.

Increase: 15% - 45% Move Speed based on the Summoner Spell's cooldown. (Higher cooldown Summoner Spells grant more Move Speed).

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

This alternative Zoe rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Taste of Blood, Grisly Mementos, Relentless Hunter. Zoe's secondary rune tree is Sorcery with Nimbus Cloak, Scorch. This setup achieves a 54.46% win rate (+6.4% win rate difference) with a 4.2% pick rate across 101 games.
54.5%Win Rate
+6.4%WR Diff
4.2%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Taste of BloodTaste of Blood

Heal when you damage an enemy champion.

Healing: 16-40 (+0.1 bonus AD, +0.05 AP) health (based on level)

Cooldown: 20s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Nimbus CloakNimbus Cloak

After casting a Summoner Spell, gain a Move Speed increase that lasts for 2s and allows you to pass through units.

Increase: 15% - 45% Move Speed based on the Summoner Spell's cooldown. (Higher cooldown Summoner Spells grant more Move Speed).

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

These champions share at least 4 runes with Zoe's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Zoe's playstyle or want to learn champions with familiar rune setups.Ahri, Neeko, Anivia, Kennen

Every Zoe Mid Keystone and Secondary Tree (Patch 26.20)

2,334 games

Zoe Mid runs Electrocute in 71% of games, with a 48.4% win rate. Summon Aery wins clearly more often (58.8% over 160 games) — worth a look when the matchup allows. Sorcery is the usual secondary tree (75%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
ElectrocuteElectrocuteMost played71.0%48.4%1,656
Dark HarvestDark Harvest16.8%44.8%393
Summon AerySummon Aery6.9%58.8%160
Stormraider's SurgeStormraider's Surge3.3%37.7%77

Secondary trees

RunePlayersWin RateGames
SorcerySorceryMost played74.9%48.2%1,748
PrecisionPrecision19.8%48.3%462
DominationDomination2.5%39.7%58

Pick rate is the share of Zoe games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Zoe Minor Runes by Tree

Every minor rune Zoe players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Grisly MementosGrisly MementosMost played81.9%48.1%1,911
Relentless HunterRelentless Hunter79.6%47.6%1,859
Sudden ImpactSudden Impact61.5%47.4%1,435
Taste of BloodTaste of Blood23.7%47.8%554
Treasure HunterTreasure Hunter6.3%47.3%146
Cheap ShotCheap Shot5.0%46.2%117

Sorcery

RunePlayersWin RateGames
Nimbus CloakNimbus CloakMost played73.7%48.9%1,719
TranscendenceTranscendence59.6%47.7%1,391
ScorchScorch26.2%50.7%612
Manaflow BandManaflow Band8.3%43.5%193
CelerityCelerity7.5%51.1%174
Gathering StormGathering Storm6.6%48.7%154

Precision

RunePlayersWin RateGames
Cut DownCut DownMost played18.1%48.8%422
Legend: HasteLegend: Haste18.0%47.3%419
Presence of MindPresence of Mind2.3%66.0%53

Zoe Stat Shards

Which stat shards Zoe players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played96.7%47.9%2,256
Attack Speed (offense)Attack Speed (offense)85.4%48.3%1,994
Health Scaling (defense)Health Scaling (defense)63.5%48.8%1,481
Health (defense)Health (defense)31.9%46.8%744
Adaptive Force (offense)Adaptive Force (offense)11.7%48.2%274
Tenacity and Slow Resist (defense)Tenacity and Slow Resist (defense)4.7%47.7%109
Move Speed (flex)Move Speed (flex)2.9%52.2%67
Ability Haste (offense)Ability Haste (offense)2.8%42.4%66
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Zoe Runes FAQ - Patch 26.20

What is the best keystone for Zoe Mid?

Electrocute: Zoe Mid takes it in 71% of ranked games and wins 48.4% of 1,656 games. Alternatives: Dark Harvest (17%, 44.8%), Summon Aery (7%, 58.8%).

What stat shards should Zoe take?

Most Zoe players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Zoe runes in patch 26.20?

The best Zoe runes in patch 26.20 use the Domination tree with Electrocute, Taste of Blood, Grisly Mementos, and Relentless Hunter, and the Sorcery tree with Nimbus Cloak and Scorch. This rune setup achieves a 67.7% win rate with a 1.3% pick rate.

What is the win rate for Zoe's best rune page?

Zoe's best rune page has a 67.7% win rate in patch 26.20, which is +19.7% compared to Zoe's average win rate. This rune setup has a 1.3% pick rate among Zoe players.

What keystone should I use on Zoe?

Electrocute from the Domination tree is the best keystone rune for Zoe in patch 26.20. This keystone synergizes well with Zoe's kit and provides a 67.7% win rate.

What is Zoe's primary rune tree?

Zoe's primary rune tree is Domination. The optimal Domination runes for Zoe are Electrocute, Taste of Blood, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Zoe's secondary rune tree?

Zoe's best secondary rune tree is Sorcery. The recommended Sorcery runes are Nimbus Cloak and Scorch, which complement Zoe's Domination primary tree.

What are alternative rune setups for Zoe?

An alternative Zoe rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Zoe's runes?

Zoe's top rune page has a 1.3% pick rate in patch 26.20. This indicates that 1.3% of Zoe players use the Electrocute setup with Domination and Sorcery trees.