Cleanse•Skill

Is Cleanse good in Slay the Spire 2?

In Slay the Spire 2, Cleanse is an uncommon skill from the Necrobinder card pool. Its effect: Summon 3. Exhaust 1 card from your Draw Pile. The data flags it as a weaker pick, settling at D tier — usually one to pass on unless your deck specifically wants it.

Over 65 tracked runs its win rate sits at 25.4%, 6.5% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 1.7% of eligible runs. Within Necrobinder runs it’s drafted 7.7% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Haunt, which lifts its win rate by +17.3% when the two share a deck. On the relic side, Festive Popper is its standout companion, worth a +22.0% win-rate swing alongside it. It costs 1 energy, gets upgraded 24.6% of the time, and tends to be picked up near floor 14.

Upgrading the card adds +2 Summon to its stat line. Of the runs that drafted it, 14 ended in victory against 41 deaths and 10 abandons. Its most common run-ender is Test Subject Boss, finishing 7.7% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Cleanse fits a Necrobinder deck.

Best Cards to Pair with Cleanse

Cleanse’s strongest card pairings so far are Haunt (+17.3%), Demesne (+16.5%), and Lethality (+16.5%), each shown with the win-rate lift it adds.

Haunt+17.3%10 runsDemesne+16.5%8 runsLethality+16.5%8 runsEnfeebling Touch+15.2%11 runsDefy+14.4%22 runsDirge+14.3%14 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Cleanse Win Rate by Class

Of the 2 classes that draft Cleanse, it performs best with Necrobinder (25.9%) and Ironclad (0.0%).

The Necrobinder25.9%64 runsThe Ironclad0.0%1 runs

Best Relics for Cleanse

The relics that swing Cleanse’s win rate the most are Festive Popper (+22.0%), Bag of Marbles (+18.9%), and Pendulum (+16.5%), with each lift shown.

Festive Popper+22.0%8 runsBag of Marbles+18.9%8 runsPendulum+16.5%9 runsAmethyst Aubergine+14.3%9 runsRed Mask+14.3%11 runsCentennial Puzzle+14.3%9 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Cleanse Card Details

A 1-energy uncommon skill, Cleanse is upgraded 24.6% of the time and tends to enter the deck around floor 14.

Summon 3. Exhaust 1 card from your Draw Pile.

Upgrade: +2 Summon

What Ends Runs with Cleanse

Runs holding Cleanse end most often against Test Subject Boss (7.7%), Knowledge Demon Boss (4.6%), and Kaiser Crab Boss (4.6%) — the share of its runs each accounts for is shown.

• Test Subject Boss7.7% of runs
• Knowledge Demon Boss4.6% of runs
• Kaiser Crab Boss4.6% of runs
• Vantom Boss3.1% of runs
• Queen Boss3.1% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.