Pillar of Creation•Power

Is Pillar of Creation good in Slay the Spire 2?

Pillar of Creation is an uncommon Regent power in Slay the Spire 2. In combat it resolves as: Whenever you create a card, gain 3 Block. It ranks among the strongest cards its class can draft right now, earning a spot at B tier in our Slay the Spire 2 card tier list.

Across 25 recorded runs, decks running it win 25.0% of the time, comfortably clear of the 12.6% average, by 12.4%. It’s a more selective pick, turning up in just 4.8% of decks that could run it. Regent players keep it in 15.1% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.

It performs best next to Manifest Authority — together they post a +75.0% swing in win rate. It also has strong chemistry with the relic Strawberry, which moves its win rate by +75.0%. At 1 energy, it’s upgraded in 25.0% of runs and usually joins the deck around floor 15.

Upgraded, it gains +1 Block, which is why so many decks invest a rest-site upgrade in it. That’s 6 wins, 18 deaths, and 1 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Waterfall Giant Boss, which closes out 8.0% of its appearances. Read on for Pillar of Creation’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Regent run.

Best Cards to Pair with Pillar of Creation

Ranked by win-rate lift, Pillar of Creation performs best alongside Manifest Authority (+75.0%), Mad Science (+75.0%), and Radiate (+50.0%).

Manifest Authority+75.0%4 runsMad Science+75.0%4 runsRadiate+50.0%4 runsBulwark+50.0%4 runsBlack Hole+41.7%6 runsEternal Armor+41.7%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Pillar of Creation Win Rate by Class

Pillar of Creation is drafted only by the Regent, where it holds a 25.0% win rate across 25 runs.

The Regentappears in 15.1% of its runs (25 tracked)

Best Relics for Pillar of Creation

Pillar of Creation pairs best with the relics Strawberry (+75.0%), Mummified Hand (+75.0%), and Ornamental Fan (+75.0%), ranked by win-rate lift.

Strawberry+75.0%3 runsMummified Hand+75.0%3 runsOrnamental Fan+75.0%3 runsPendulum+75.0%5 runsBronze Scales+75.0%3 runsRed Mask+50.0%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Pillar of Creation Card Details

Pillar of Creation is an uncommon power costing 1 energy; it’s upgraded in 25.0% of runs and usually picked up by floor 15.

Whenever you create a card, gain 3 Block.

Upgrade: +1 Block

What Ends Runs with Pillar of Creation

Pillar of Creation’s most common run-enders are Waterfall Giant Boss (8.0%), Byrdonis Elite (8.0%), and Bygone Effigy Elite (8.0%).

• Waterfall Giant Boss8.0% of runs
• Byrdonis Elite8.0% of runs
• Bygone Effigy Elite8.0% of runs
• Skulking Colony Elite8.0% of runs

See Also

Compare Pillar of Creation with the rest of the best Slay the Spire 2 cards, relics, and classes below.