Lissandra - League of Legends Champion
Win Rate
50.2%
Pick Rate
1.7%

Lissandravs Leona

BMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Lissandra vs Leona is a decisive matchup in LoL patch 26.14. Leona wins with a 60.0% win rate (+20.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Leona scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Leona matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 40.0% win rate in this matchup
Lissandra
40.0% WR
VS
Leona vs Lissandra matchup - 60.0% win rate
Leona
60.0% WR

Who Wins the Lissandra vs Leona Matchup?

Leona wins the Lissandra vs Leona matchup
Winner
Leona
Matches: 5
40.0%
Win Rate
60.0%
1.7
CS / min
1.2
558
DMG / min
454
5,765
Gold / game
5,480
89
Heal / min
136
347
DMG Mitigated / min
1,424
1.9
CC / min
1.9
50.0%
Early Game WR
50.0%
0.0%
Late Game WR
100.0%

Lissandra vs Leona Matchup Summary

The Lissandra vs Leona matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Leona wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Leona a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Leona outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Leona reaches their power spikes, while Leona should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Leona leads by 1,124 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Leona has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Leona overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Leona Laning Phase Breakdown

Lissandra wins the laning phase against Leona in League of Legends

Lissandra is favored during the laning phase against Leona, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.7Lissandra
1.2Leona
Lissandra edges out Leona by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Lissandra.
Damage
558Lissandra
454Leona
Lissandra heavily out-damages Leona by 104 DMG/min, dominating both short trades and all-in fights. Leona should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
5,765Lissandra
5,480Leona
Lissandra and Leona generate nearly equal gold per game, with just a 285 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.9Lissandra
1.9Leona
Both Lissandra and Leona provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
435Lissandra
1,560Leona
Leona vastly out-sustains Lissandra, healing and mitigating 1,124 more damage per minute. This massive durability gap means Leona can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Lissandra
50.0%
+0.0% advantage
Lissandra early game win rateLissandra50.0%
Leona early game win rateLeona50.0%
Late Game
Leona
100.0%
+100.0% advantage
Lissandra late game win rateLissandra0.0%
Leona late game win rateLeona100.0%

The early game (first 15 minutes) is a toss-up between Lissandra and Leona, with Lissandra holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Leona is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Leona, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Lissandra has the edge early, but Leona gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Lissandra Runes Against Leona

Domination rune tree - Lissandra primary runes vs LeonaDomination
Electrocute - best Lissandra rune vs LeonaCheap Shot - best Lissandra rune vs LeonaGrisly Mementos - best Lissandra rune vs LeonaUltimate Hunter - best Lissandra rune vs Leona
Sorcery rune tree - Lissandra secondary runes vs LeonaSorcery
Manaflow Band - best Lissandra rune vs LeonaTranscendence - best Lissandra rune vs Leona
100.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Leona in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.14. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
62.22%456.484911,48773.7%53.9%
65.00%407.190012,18566.7%63.6%
47.06%346.689111,06457.1%40.0%
58.06%316.979110,55552.9%64.3%
55.56%276.884213,85877.8%44.4%
51.85%276.390310,35241.7%60.0%
44.00%256.473011,99228.6%50.0%
52.00%256.694112,41350.0%52.9%
47.83%236.88059,91335.7%66.7%
45.45%226.977111,01946.1%44.4%
28.57%216.769011,05228.6%28.6%
45.00%206.078912,2360.0%60.0%
50.00%206.783512,83340.0%53.3%
42.11%196.584710,93833.3%46.1%
52.94%176.475311,19533.3%63.6%
57.14%146.378810,31971.4%42.9%
50.00%146.793912,13040.0%55.6%
57.14%146.773910,99757.1%57.1%
45.45%117.090111,16360.0%33.3%
45.45%117.187812,49250.0%42.9%
45.45%114.57409,87540.0%50.0%
60.00%107.093011,03360.0%60.0%
40.00%106.370710,52750.0%25.0%
44.44%96.695112,88850.0%42.9%
55.56%96.481011,06466.7%50.0%
33.33%97.369511,41550.0%28.6%
25.00%86.570212,0800.0%28.6%
62.50%86.71,01613,65375.0%50.0%
75.00%87.11,06413,712100.0%66.7%
75.00%86.278110,08833.3%100.0%
85.71%77.496113,984100.0%80.0%
57.14%75.597511,52366.7%50.0%
14.29%76.383312,1060.0%16.7%
71.43%76.667610,12666.7%75.0%
66.67%67.181812,647100.0%60.0%
83.33%66.999013,827100.0%75.0%
50.00%66.07047,95666.7%33.3%
33.33%66.91,05110,52633.3%33.3%
33.33%66.71,02715,0690.0%33.3%
40.00%56.987412,25150.0%33.3%
40.00%55.16269,32550.0%33.3%
40.00%54.91,02512,6540.0%50.0%
20.00%53.774610,6910.0%50.0%
20.00%56.271812,3140.0%20.0%
40.00%51.75585,76550.0%0.0%

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Lissandra vs Leona - Frequently Asked Questions

How does Lissandra do against Leona in League of Legends?

Leona wins the Lissandra vs Leona matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.14.

How does Lissandra do against Leona in the early game?

In the early game, Lissandra has the advantage against Leona with a 50.0% win rate versus 50.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Leona in the late game?

In the late game, Leona takes over the Lissandra vs Leona matchup with a 100.0% win rate compared to 0.0%. Leona scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Leona matchup?

Leona wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.14. The 20.0 percentage point advantage means Leona is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Leona?

The best Lissandra build against Leona includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Leona?

The best Lissandra runes against Leona use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Leona matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Leona?

No, Lissandra struggles against Leona with only a 40.0% win rate. Leona has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Leona's lead.

How do I play Lissandra against Leona?

When playing Lissandra against Leona, play cautiously and avoid Leona's power spikes. Look for jungle assistance and team-dependent plays since Leona has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.