Lissandra - League of Legends Champion
Win Rate
50.4%
Pick Rate
1.7%

Lissandravs Milio

BMage
Patch26.14
Matches491,560
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Lissandra vs Milio is a decisive matchup in LoL patch 26.14. Lissandra wins with a 66.7% win rate (+33.3%) over Milio based on 6 games. Lissandra holds the advantage in both the early and late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Milio matchup.

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Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Lissandra - 66.7% win rate in this matchup
Lissandra
66.7% WR
VS
Milio vs Lissandra matchup - 33.3% win rate
Milio
33.3% WR

Who Wins the Lissandra vs Milio Matchup?

Lissandra wins the Lissandra vs Milio matchup
Winner
Lissandra
Matches: 6
66.7%
Win Rate
33.3%
2.8
CS / min
1.7
607
DMG / min
281
9,991
Gold / game
8,708
140
Heal / min
353
348
DMG Mitigated / min
378
1.8
CC / min
0.7
100.0%
Early Game WR
0.0%
50.0%
Late Game WR
50.0%

Lissandra vs Milio Matchup Summary

The Lissandra vs Milio matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Lissandra wins with a 66.7% win rate compared to Milio's 33.3%, giving Lissandra a 33.3 percentage point advantage. Lissandra dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Milio players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in crowd control, where Lissandra leads by 1.1s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Lissandra players can confidently pick into Milio and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Milio away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Milio Laning Phase Breakdown

Lissandra wins the laning phase against Milio in League of Legends

Lissandra is favored during the laning phase against Milio, winning 4 out of 5 key stat categories. Lissandra holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
2.8Lissandra
1.7Milio
Lissandra significantly out-farms Milio by 1.1 CS per minute, accumulating an estimated 17 CS lead by mid game. This substantial farming gap gives Lissandra a major gold advantage and earlier item completions. Milio players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
607Lissandra
281Milio
Lissandra heavily out-damages Milio by 327 DMG/min, dominating both short trades and all-in fights. Milio should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Lissandra's sustained damage advantage take over.
Economy
9,991Lissandra
8,708Milio
Lissandra generates a commanding 1,283 more gold per game than Milio. This substantial economic advantage means Lissandra consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Milio should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.8Lissandra
0.7Milio
Lissandra brings significantly more crowd control than Milio, with 1.1 more seconds of CC per minute. This large utility gap makes Lissandra far more valuable in setting up jungle ganks, controlling objectives, and locking down targets in team fights. Milio should invest in tenacity and position carefully to avoid being chain-CC'd.
Sustain
488Lissandra
731Milio
Milio vastly out-sustains Lissandra, healing and mitigating 243 more damage per minute. This massive durability gap means Milio can absorb significant punishment and remain in lane while Lissandra is forced to recall. Building grievous wounds early is essential for Lissandra, and focusing on burst trade patterns rather than sustained fights is critical.

Best Lissandra Build Against Milio

Sorcerer's Shoes is the optimal boots choice against Milio, providing the mobility and stats Lissandra needs most in this matchup. The top-performing core items for Lissandra against Milio are Luden's Echo, Void Staff and Malignance. This combination gives Lissandra an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Lissandra vs Milio matchup.

Early Game vs Late Game

Early Game
Lissandra
100.0%
+100.0% advantage
Lissandra early game win rateLissandra100.0%
Milio early game win rateMilio0.0%
Late Game
Lissandra
50.0%
+0.0% advantage
Lissandra late game win rateLissandra50.0%
Milio late game win rateMilio50.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Milio. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Lissandra at 50.0% win rate — only 0.0 points ahead of Milio. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

Lissandra holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Milio players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Lissandra Runes Against Milio

Domination rune tree - Lissandra primary runes vs MilioDomination
Dark Harvest - best Lissandra rune vs MilioCheap Shot - best Lissandra rune vs MilioGrisly Mementos - best Lissandra rune vs MilioUltimate Hunter - best Lissandra rune vs Milio
Sorcery rune tree - Lissandra secondary runes vs MilioSorcery
Transcendence - best Lissandra rune vs MilioScorch - best Lissandra rune vs Milio
66.7% WR

Running Domination primary with Sorcery secondary allows Lissandra to press their advantage against Milio, amplifying the strengths that make this a favorable matchup.


Lissandra matchup data for League of Legends patch 26.14. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
56.00%1006.882911,70950.0%60.0%
54.88%826.590211,76663.3%50.0%
48.15%816.587811,63150.0%46.8%
55.07%696.780112,59753.6%56.1%
43.55%626.673910,94353.9%36.1%
56.45%626.780810,82951.9%60.0%
54.39%576.388510,87848.1%60.0%
49.12%576.790211,34841.7%54.5%
46.15%526.686710,75050.0%42.9%
42.00%506.883311,88752.4%34.5%
54.76%426.788411,04464.7%48.0%
51.28%395.570811,60125.0%63.0%
50.00%386.677811,40442.9%54.2%
44.44%366.671011,33130.8%52.2%
45.45%336.881012,15938.5%50.0%
33.33%276.072311,76540.0%31.8%
44.44%276.777012,01450.0%42.1%
62.96%276.383710,83475.0%53.3%
64.00%256.974910,01473.3%50.0%
47.83%236.492011,17444.4%50.0%
45.45%226.785912,50133.3%50.0%
50.00%226.279312,36850.0%50.0%
57.14%216.381813,51980.0%50.0%
61.90%216.890211,20380.0%45.5%
72.22%186.677311,19650.0%90.0%
50.00%186.697313,12450.0%50.0%
76.47%177.087313,897100.0%71.4%
41.18%176.589312,80260.0%33.3%
58.82%176.284911,48685.7%40.0%
41.18%176.175310,54540.0%41.7%
46.67%156.480510,47440.0%50.0%
46.67%157.078512,21266.7%41.7%
57.14%146.481012,30166.7%54.5%
42.86%146.979311,28742.9%42.9%
46.15%134.17129,62942.9%50.0%
61.54%136.991813,162100.0%50.0%
16.67%126.79369,20416.7%16.7%
63.64%117.095613,587100.0%50.0%
54.55%116.384011,6570.0%75.0%
27.27%116.891713,30433.3%25.0%
66.67%95.193511,97080.0%50.0%
44.44%96.880212,256100.0%28.6%
77.78%96.788814,322100.0%71.4%
33.33%96.47468,58540.0%25.0%
66.67%96.87559,92940.0%100.0%
55.56%97.384311,38566.7%50.0%
44.44%97.01,00813,81266.7%33.3%
87.50%86.71,21811,330100.0%66.7%
37.50%86.488010,16050.0%33.3%
42.86%74.673111,07625.0%66.7%
57.14%72.06357,01560.0%50.0%
33.33%65.382710,99950.0%25.0%
33.33%67.01,16514,7130.0%33.3%
50.00%65.885012,748100.0%25.0%
50.00%66.476310,65033.3%66.7%
66.67%62.86079,991100.0%50.0%
33.33%65.390911,5150.0%50.0%
20.00%51.84187,0570.0%100.0%
20.00%55.865910,91350.0%0.0%
80.00%56.792012,965100.0%66.7%
40.00%54.91,02512,6540.0%50.0%
40.00%53.163812,160100.0%25.0%
40.00%57.21,22913,57550.0%33.3%
40.00%55.872314,8620.0%40.0%
60.00%56.27519,297100.0%33.3%
100.00%57.21,07011,231100.0%100.0%

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Lissandra vs Milio - Frequently Asked Questions

How does Lissandra do against Milio in League of Legends?

Lissandra wins the Lissandra vs Milio matchup with a 66.7% win rate compared to Milio's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.14.

How does Lissandra do against Milio in the early game?

In the early game, Lissandra has the advantage against Milio with a 100.0% win rate versus 0.0%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Milio in the late game?

In the late game, Lissandra takes over the Lissandra vs Milio matchup with a 50.0% win rate compared to 50.0%. Lissandra scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Milio matchup?

Lissandra wins the matchup against Milio with a 66.7% win rate in League of Legends patch 26.14. The 33.3 percentage point advantage means Lissandra is significantly favored in this lane matchup based on 6 games analyzed.

What is the best Lissandra build against Milio?

The best Lissandra build against Milio includes Luden's Echo, Void Staff, Malignance with Sorcerer's Shoes. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Milio?

The best Lissandra runes against Milio use the Domination primary tree with Sorcery secondary. This rune setup achieves a 66.7% win rate in the Lissandra vs Milio matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Milio?

Yes, Lissandra has a favorable matchup against Milio with a 66.7% win rate. Lissandra strongly counters Milio in lane based on current patch 26.14 data.

How do I play Lissandra against Milio?

When playing Lissandra against Milio, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.