Vayne - League of Legends Champion
Win Rate
50.7%
Pick Rate
4.7%

Vaynevs Locke

BMarksmanAssassin
Patch26.13
Matches177,854
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 27, 2026
MethodologyData Methodology

Vayne vs Locke is a decisive matchup in LoL patch 26.13. Vayne wins with a 80.0% win rate (+60.0%) over Locke based on 10 games. Vayne holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Locke matchup.

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Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Vayne - 80.0% win rate in this matchup
Vayne
80.0% WR
VS
Locke vs Vayne matchup - 20.0% win rate
Locke
20.0% WR

Who Wins the Vayne vs Locke Matchup?

Vayne wins the Vayne vs Locke matchup
Winner
Vayne
Matches: 10
80.0%
Win Rate
20.0%
5.7
CS / min
5.4
1,189
DMG / min
705
12,002
Gold / game
10,026
263
Heal / min
322
490
DMG Mitigated / min
720
0.5
CC / min
0.4
83.3%
Early Game WR
16.7%
75.0%
Late Game WR
25.0%

Vayne vs Locke Matchup Summary

The Vayne vs Locke matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Vayne wins with a 80.0% win rate compared to Locke's 20.0%, giving Vayne a 60.0 percentage point advantage. Vayne dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Locke players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Vayne leads by 484 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Vayne players can confidently pick into Locke and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Locke away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Locke Laning Phase Breakdown

Vayne wins the laning phase against Locke in League of Legends

Vayne is favored during the laning phase against Locke, winning 4 out of 5 key stat categories. Vayne holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
5.7Vayne
5.4Locke
Vayne edges out Locke by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Vayne.
Damage
1,189Vayne
705Locke
Vayne heavily out-damages Locke by 484 DMG/min, dominating both short trades and all-in fights. Locke should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
12,002Vayne
10,026Locke
Vayne generates a commanding 1,976 more gold per game than Locke. This substantial economic advantage means Vayne consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Locke should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.5Vayne
0.4Locke
Both Vayne and Locke provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
753Vayne
1,042Locke
Locke vastly out-sustains Vayne, healing and mitigating 289 more damage per minute. This massive durability gap means Locke can absorb significant punishment and remain in lane while Vayne is forced to recall. Building grievous wounds early is essential for Vayne, and focusing on burst trade patterns rather than sustained fights is critical.

Best Vayne Build Against Locke

Berserker's Greaves is the optimal boots choice against Locke, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Locke are Jak'Sho, The Protean, Blade of The Ruined King and Guinsoo's Rageblade. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Locke. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Locke matchup.

Early Game vs Late Game

Early Game
Vayne
83.3%
+66.7% advantage
Vayne early game win rateVayne83.3%
Locke early game win rateLocke16.7%
Late Game
Vayne
75.0%
+50.0% advantage
Vayne late game win rateVayne75.0%
Locke late game win rateLocke25.0%

Vayne dominates the early game (first 15 minutes) with a commanding 83.3% win rate — a 66.7 percentage point lead over Locke. This lopsided early game means Vayne can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Vayne is far superior in the late game (25+ minutes), boasting a 75.0% win rate — 50.0 points above Locke. Extended games heavily favor Vayne, whose kit and scaling make them a dominant force in team fights and objective control.

Vayne holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Locke players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Locke

Precision rune tree - Vayne primary runes vs LockePrecision
Press the Attack - best Vayne rune vs LockeTriumph - best Vayne rune vs LockeLegend: Alacrity - best Vayne rune vs LockeLast Stand - best Vayne rune vs Locke
Inspiration rune tree - Vayne secondary runes vs LockeInspiration
Magical Footwear - best Vayne rune vs LockeCosmic Insight - best Vayne rune vs Locke
100.0% WR

Running Precision primary with Inspiration secondary allows Vayne to press their advantage against Locke, amplifying the strengths that make this a favorable matchup.


Vayne matchup data for League of Legends patch 26.13. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.13
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
57.01%1075.978512,87957.7%56.4%
38.78%985.571312,31430.0%44.8%
48.35%915.984512,90150.0%47.2%
50.00%766.080211,57360.0%41.5%
56.58%766.382212,99254.5%58.1%
61.11%725.989113,24363.0%60.0%
43.14%516.387513,41240.9%44.8%
45.10%516.179211,61346.4%43.5%
58.70%466.085513,21652.9%62.1%
52.27%446.185712,68950.0%53.9%
36.84%386.078611,97626.3%47.4%
62.86%356.082012,87468.8%57.9%
30.30%336.71,09511,99926.7%33.3%
53.13%325.975912,61856.3%50.0%
51.72%296.172911,48652.9%50.0%
38.46%266.778611,13341.2%33.3%
56.00%255.778413,09463.6%50.0%
47.83%235.856410,67850.0%46.1%
52.17%235.977312,13554.5%50.0%
63.64%226.471611,64166.7%60.0%
45.45%226.41,01412,52340.0%50.0%
59.09%225.01,06011,94071.4%53.3%
40.91%224.962010,27528.6%46.7%
47.62%215.991513,46650.0%44.4%
60.00%206.571212,21840.0%80.0%
57.89%196.593515,21862.5%54.5%
47.37%195.475210,95936.4%62.5%
31.58%195.68219,16536.4%25.0%
68.75%165.91,04914,22071.4%66.7%
43.75%165.71,00812,54320.0%54.5%
57.14%145.792815,36950.0%62.5%
46.15%135.71,03510,41842.9%50.0%
61.54%136.079613,69250.0%71.4%
53.85%136.41,07313,05833.3%60.0%
41.67%126.083914,01850.0%37.5%
58.33%125.787511,87360.0%57.1%
58.33%125.999312,07150.0%66.7%
18.18%115.95969,2790.0%50.0%
54.55%115.81,45512,35033.3%62.5%
45.45%116.41,01311,26460.0%33.3%
60.00%106.894312,23975.0%50.0%
60.00%106.186010,58450.0%75.0%
30.00%105.785712,51425.0%33.3%
80.00%105.71,18912,00283.3%75.0%
50.00%106.41,09913,00866.7%42.9%
44.44%96.070510,44116.7%100.0%
66.67%96.487710,66050.0%80.0%
50.00%86.41,00711,76360.0%33.3%
50.00%85.388213,05466.7%40.0%
12.50%85.082710,2110.0%20.0%
28.57%76.886510,23566.7%0.0%
71.43%76.51,19612,04260.0%100.0%
28.57%75.796614,13450.0%20.0%
57.14%76.51,17412,31966.7%50.0%
71.43%77.399613,04366.7%75.0%
42.86%74.778212,42633.3%50.0%
28.57%75.77119,33225.0%33.3%
42.86%76.084115,29250.0%40.0%
28.57%77.487012,68333.3%25.0%
57.14%76.293611,80466.7%50.0%
50.00%66.11,03717,4040.0%60.0%
83.33%65.279213,066100.0%80.0%
66.67%65.01,06713,20850.0%75.0%
83.33%66.61,03015,125100.0%75.0%
83.33%67.261114,2890.0%83.3%
80.00%55.488613,365100.0%50.0%
20.00%56.11,25215,1720.0%25.0%
60.00%54.755811,122100.0%33.3%
20.00%56.573711,65225.0%0.0%
40.00%56.31,00015,0350.0%40.0%

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Vayne vs Locke - Frequently Asked Questions

How does Vayne do against Locke in League of Legends?

Vayne wins the Vayne vs Locke matchup with a 80.0% win rate compared to Locke's 20.0%, a 60.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.13.

How does Vayne do against Locke in the early game?

In the early game, Vayne has the advantage against Locke with a 83.3% win rate versus 16.7%. Vayne players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Locke in the late game?

In the late game, Vayne takes over the Vayne vs Locke matchup with a 75.0% win rate compared to 25.0%. Vayne scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Locke matchup?

Vayne wins the matchup against Locke with a 80.0% win rate in League of Legends patch 26.13. The 60.0 percentage point advantage means Vayne is significantly favored in this lane matchup based on 10 games analyzed.

What is the best Vayne build against Locke?

The best Vayne build against Locke includes Jak'Sho, The Protean, Blade of The Ruined King, Guinsoo's Rageblade with Berserker's Greaves. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Locke?

The best Vayne runes against Locke use the Precision primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Locke matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Locke?

Yes, Vayne has a favorable matchup against Locke with a 80.0% win rate. Vayne strongly counters Locke in lane based on current patch 26.13 data.

How do I play Vayne against Locke?

When playing Vayne against Locke, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.