Adrenaline•Skill

Is Adrenaline good in Slay the Spire 2?

In Slay the Spire 2, Adrenaline is a rare skill from the Silent card pool. Its effect: Gain Energy. Draw 2 cards. Right now it’s a premium pick that sits at S tier — one of the better cards you can add to a deck this run.

Over 108 tracked runs its win rate sits at 42.2%, 23.2% ahead of the 18.9% all-deck baseline. It sees niche play, included in only 2.9% of eligible runs. Within Regent runs it’s drafted 0.3% of the time, making it a regular part of that class’s decks. Decks that include it run about 1.1 copies on average.

Its standout pairing so far is Serpent Form, which lifts its win rate by +23.9% when the two share a deck. On the relic side, Pantograph is its standout companion, worth a +27.0% win-rate swing alongside it. It costs 0 energy, gets upgraded 44.0% of the time, and tends to be picked up near floor 18.

Upgrading the card adds +1 Energy to its stat line. Of the runs that drafted it, 43 ended in victory against 59 deaths and 6 abandons. Its most common run-ender is Queen Boss, finishing 7.4% of the runs it shows up in. See the synergies, class split, and threats below for the full picture of where Adrenaline fits a Silent deck.

Best Cards to Pair with Adrenaline

Adrenaline’s strongest card pairings so far are Serpent Form (+23.9%), Reflex (+22.7%), and Knife Trap (+19.6%), each shown with the win-rate lift it adds.

Serpent Form+23.9%10 runsReflex+22.7%16 runsKnife Trap+19.6%13 runsAfterimage+18.5%25 runsTactician+16.6%23 runsMalaise+16.5%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Adrenaline Win Rate by Class

Of the 5 classes that draft Adrenaline, it performs best with Regent (50.0%), Silent (43.2%), and Ironclad (33.3%).

The Regent50.0%2 runsThe Silent43.2%101 runsThe Ironclad33.3%3 runsThe Necrobinder0.0%1 runsThe Defect0.0%1 runs

Best Relics for Adrenaline

The relics that swing Adrenaline’s win rate the most are Pantograph (+27.0%), Potion Belt (+21.9%), and Signet Ring (+21.7%), with each lift shown.

Pantograph+27.0%12 runsPotion Belt+21.9%22 runsSignet Ring+21.7%6 runsPendulum+20.2%16 runsLasting Candy+20.1%8 runsSai+19.3%5 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Adrenaline Card Details

A 0-energy rare skill, Adrenaline is upgraded 44.0% of the time and tends to enter the deck around floor 18.

Gain Energy. Draw 2 cards.

Upgrade: +1 Energy

What Ends Runs with Adrenaline

Runs holding Adrenaline end most often against Queen Boss (7.4%), Entomancer Elite (5.6%), and Lagavulin Matriarch Boss (4.6%) — the share of its runs each accounts for is shown.

• Queen Boss7.4% of runs
• Entomancer Elite5.6% of runs
• Lagavulin Matriarch Boss4.6% of runs
• Test Subject Boss4.6% of runs
• Knowledge Demon Boss2.8% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.