Vexing Puzzlebox•Relic

Is Vexing Puzzlebox good in Slay the Spire 2?

In Slay the Spire 2, Vexing Puzzlebox is a rare relic you can pick up on your climb. Its effect: At the start of each combat, add a random card into your Hand. It's free to play this turn. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 220 tracked runs the win rate of decks holding it sits at 36.4%, 22.3% ahead of the 14.1% all-run baseline. It sees lighter play, carried in only 2.1% of runs. It does its best work in the hands of the Silent, who post a 43.1% win rate with it. Within Silent runs specifically, it’s carried 2.3% of the time.

Its standout card pairing is Abrasive, which lifts the relic’s win rate by +23.6% when both are in play. It also works nicely with Hidden Daggers, good for a +23.6% win-rate change. It typically enters the deck near floor 23. As a rare relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 79 ended in victory while 138 fell to a defeat. Its most common run-ender is Test Subject Boss, finishing 10.9% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Vexing Puzzlebox is worth grabbing.

Pick or Skip: Vexing Puzzlebox

Players take Vexing Puzzlebox in 64.4% of the 343 offers it appears in; those runs win 36.7% against 30.8% for runs that passed, a pick lift of +5.6% over 218 decided runs.

Taken 221 times out of 343 offers.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Vexing Puzzlebox

The cards that gain the most from carrying Vexing Puzzlebox are Abrasive (+23.6%), Hidden Daggers (+23.6%), and Fan of Knives (+23.6%), each shown with its win-rate swing.

Abrasive+23.6%16 runsHidden Daggers+23.6%15 runsFan of Knives+23.6%16 runsSlice+22.4%17 runsBackflip+21.3%27 runsFootwork+17.8%25 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Vexing Puzzlebox Win Rate by Class

Of the 5 classes that carry Vexing Puzzlebox, it performs best with Silent (43.1%), Necrobinder (42.1%), and Ironclad (36.5%).

The Silent43.1%60 runsThe Necrobinder42.1%38 runsThe Ironclad36.5%53 runsThe Regent33.3%36 runsThe Defect21.9%32 runs

Vexing Puzzlebox Details

Carried in 2.1% of runs, Vexing Puzzlebox is a rare relic typically acquired near floor 23.

At the start of each combat, add a random card into your Hand. It's free to play this turn.

What Ends Runs with Vexing Puzzlebox

Runs carrying Vexing Puzzlebox end most often against Test Subject Boss (10.9%), Aeonglass Boss (7.3%), and Queen Boss (7.3%) — the share of its runs each accounts for is shown.

• Test Subject Boss10.9% of runs
• Aeonglass Boss7.3% of runs
• Queen Boss7.3% of runs
• Knowledge Demon Boss7.3% of runs
• The Insatiable Boss3.6% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.