Vexing Puzzlebox
Win Rate
40.0%
Pick Rate
2.2%
Δ vs Avg
+21.1

Vexing PuzzleboxRelic

Rare
RarityRare
MethodologyData Methodology

At the start of each combat, add a random card into your Hand. It's free to play this turn.

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Is Vexing Puzzlebox good in Slay the Spire 2?

In Slay the Spire 2, Vexing Puzzlebox is a rare relic you can pick up on your climb. Its effect: At the start of each combat, add a random card into your Hand. It's free to play this turn. Performance-wise it’s a steady, unspectacular pick rated C tier overall.

Over 82 tracked runs the win rate of decks holding it sits at 40.0%, 21.1% ahead of the 18.9% all-run baseline. It sees lighter play, carried in only 2.2% of runs. It does its best work in the hands of the Necrobinder, who post a 53.3% win rate with it. Within Necrobinder runs specifically, it’s carried 1.8% of the time.

Its standout card pairing is Spur, which lifts the relic’s win rate by +60.0% when both are in play. It also works nicely with I Am Invincible, good for a +60.0% win-rate change. It typically enters the deck near floor 24. As a rare relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 32 ended in victory while 48 fell to a defeat. Its most common run-ender is Knowledge Demon Boss, finishing 9.8% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Vexing Puzzlebox is worth grabbing.

Vexing Puzzlebox Win Rate & Pick Rate

At a 40.0% win rate, Vexing Puzzlebox runs 21.1% ahead of the 18.9% all-run baseline — the bars below put the two side by side.

Win rate40.0%
Average run18.9%
+21.1% vs averagePick rate: 2.2%82 runs

Run Outcomes with Vexing Puzzlebox

Across the 82 runs that carried Vexing Puzzlebox, 32 ended in a win and 50 in a loss — a 39.0% win share, counting abandons as losses.

  • Wins 39.0%
  • Losses 61.0%

Best Cards with Vexing Puzzlebox

The cards that gain the most from carrying Vexing Puzzlebox are Spur (+60.0%), I Am Invincible (+60.0%), and Oblivion (+60.0%), each shown with its win-rate swing.

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Vexing Puzzlebox Win Rate by Class

Of the 5 classes that carry Vexing Puzzlebox, it performs best with Necrobinder (53.3%), Silent (44.4%), and Ironclad (37.5%).

Vexing Puzzlebox Details

Carried in 2.2% of runs, Vexing Puzzlebox is a rare relic typically acquired near floor 24.

At the start of each combat, add a random card into your Hand. It's free to play this turn.

RarityRare
Typical pickup floor24
Pick rate2.2%
Runs tracked82

What Ends Runs with Vexing Puzzlebox

Runs carrying Vexing Puzzlebox end most often against Knowledge Demon Boss (9.8%), Test Subject Boss (7.3%), and Queen Boss (6.1%) — the share of its runs each accounts for is shown.

  • Knowledge Demon Boss9.8% of runs
  • Test Subject Boss7.3% of runs
  • Queen Boss6.1% of runs
  • Kaiser Crab Boss3.7% of runs
  • Lagavulin Matriarch Boss2.4% of runs
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Vexing Puzzlebox – Frequently Asked Questions

Is Vexing Puzzlebox good in Slay the Spire 2?

Across 82 tracked runs carrying it, Vexing Puzzlebox wins 40.0% of the time — +21.1% above the average run. Win rate reflects how often runs with the relic end in victory.

What does Vexing Puzzlebox do in Slay the Spire 2?

At the start of each combat, add a random card into your Hand. It's free to play this turn.

How rare is Vexing Puzzlebox in Slay the Spire 2?

Vexing Puzzlebox is a Rare relic, picked up in 2.2% of tracked runs.

What is the best card to use with Vexing Puzzlebox?

In tracked runs, Vexing Puzzlebox has performed best alongside Spur, which lifts its win rate by +60.0% over 3 runs together.

Which class is Vexing Puzzlebox best in?

Vexing Puzzlebox has its highest win rate with The Necrobinder (53.3%).

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.