- Win Rate
- 52.1%
- Pick Rate
- 0.8%
- Ban Rate
- 1.5%
Anivia Mid Runes: Keystone & Shards
- Patch
- 26.20
- Games
- 1,109
- Lane
- Mid
- Tier
- All Tiers
- Last Updated
- Oct 12, 2026 UTC
- Methodology
- Data Methodology
- Author
- Dakota Chinnick
Best Mid Anivia runes for LoL Patch 26.20 - Electrocute from the Domination tree with Precision secondary (50.4% WR, 20.4% pick rate). Anivia's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Secondary tree: Coup de Grace, Presence of Mind.
Primary Tree
Domination
ElectrocuteHitting a champion with 3 separate attacks or abilities within 3s deals bonus
Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s
'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'
Cheap ShotDamaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).
Cooldown: 4s
Grisly MementosCollect 1 memento on champion
Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.
Relentless HunterGain
Coup de GraceDeal 8% more damage to champions who have less than 40% health.
Presence of MindDamaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.
Takedowns restore 15% of your maximum mana or energy.
Cooldown for damage restoration: 8s
Primary Tree
Domination
ElectrocuteHitting a champion with 3 separate attacks or abilities within 3s deals bonus
Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s
'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'
Cheap ShotDamaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).
Cooldown: 4s
Grisly MementosCollect 1 memento on champion
Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.
Relentless HunterGain
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Cooldown: 15 seconds
ScorchYour next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.
Cooldown: 10s
Every Anivia Mid Keystone and Secondary Tree (Patch 26.20)
1,084 gamesAnivia Mid runs Electrocute in 72% of games, with a 51.6% win rate. Precision is the usual secondary tree (65%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).
Keystones
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| ElectrocuteMost played | 71.7% | 51.6% | 777 |
 Arcane Comet | 13.9% | 53.0% | 151 |
 Deathfire Touch | 10.4% | 55.8% | 113 |
Secondary trees
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 PrecisionMost played | 64.7% | 53.5% | 701 |
 Sorcery | 29.1% | 48.9% | 315 |
Pick rate is the share of Anivia games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.
Anivia Minor Runes by Tree
Every minor rune Anivia players take, grouped by rune tree, with how often it is picked and how often it wins.
Domination
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Cheap ShotMost played | 72.2% | 51.7% | 783 |
| Relentless Hunter | 67.7% | 51.6% | 734 |
| Grisly Mementos | 62.7% | 51.0% | 680 |
 Sixth Sense | 6.1% | 53.0% | 66 |
 Treasure Hunter | 4.5% | 57.1% | 49 |
 Deep Ward | 4.2% | 60.0% | 45 |
Precision
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Presence of MindMost played | 62.6% | 53.3% | 679 |
| Coup de Grace | 50.6% | 53.0% | 549 |
 Cut Down | 11.8% | 52.3% | 128 |
Sorcery
| Rune | Players | Win Rate | Games |
|---|---|---|---|
| Manaflow BandMost played | 53.0% | 51.4% | 574 |
| Scorch | 46.1% | 49.8% | 500 |
 Transcendence | 22.0% | 53.6% | 239 |
 Gathering Storm | 8.0% | 58.6% | 87 |
 Celerity | 4.5% | 57.1% | 49 |
Anivia Stat Shards
Which stat shards Anivia players choose in each of the three shard rows, and the win rate of each.
| Rune | Players | Win Rate | Games |
|---|---|---|---|
 Adaptive Force (flex)Most played | 91.1% | 51.2% | 988 |
 Health Scaling (defense) | 82.7% | 51.2% | 896 |
 Attack Speed (offense) | 74.0% | 50.9% | 802 |
| Adaptive Force (offense) | 23.2% | 53.2% | 252 |
| Health (defense) | 13.4% | 55.2% | 145 |
 Move Speed (flex) | 7.1% | 59.7% | 77 |
 Tenacity and Slow Resist (defense) | 4.0% | 60.5% | 43 |
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Anivia Runes FAQ - Patch 26.20
What is the best keystone for Anivia Mid?
Electrocute: Anivia Mid takes it in 72% of ranked games and wins 51.6% of 777 games. Alternatives: Arcane Comet (14%, 53.0%), Deathfire Touch (10%, 55.8%).
What stat shards should Anivia take?
Most Anivia players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.
What are the best Anivia runes in patch 26.20?
The best Anivia runes in patch 26.20 use the Domination tree with Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, and the Precision tree with Coup de Grace and Presence of Mind. This rune setup achieves a 50.4% win rate with a 20.4% pick rate.
What is the win rate for Anivia's best rune page?
Anivia's best rune page has a 50.4% win rate in patch 26.20, which is -1.7% compared to Anivia's average win rate. This rune setup has a 20.4% pick rate among Anivia players.
What keystone should I use on Anivia?
Electrocute from the Domination tree is the best keystone rune for Anivia in patch 26.20. This keystone synergizes well with Anivia's kit and provides a 50.4% win rate.
What is Anivia's primary rune tree?
Anivia's primary rune tree is Domination. The optimal Domination runes for Anivia are Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.
What is Anivia's secondary rune tree?
Anivia's best secondary rune tree is Precision. The recommended Precision runes are Coup de Grace and Presence of Mind, which complement Anivia's Domination primary tree.
What are alternative rune setups for Anivia?
An alternative Anivia rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.
How popular are Anivia's runes?
Anivia's top rune page has a 20.4% pick rate in patch 26.20. This indicates that 20.4% of Anivia players use the Electrocute setup with Domination and Precision trees.