Anivia, League of Legends champion
Win Rate
54.3%
Pick Rate
0.9%
Ban Rate
1.7%

Anivia Mid Runes: Keystone & Shards

Anivia B TierMage
Patch
26.20
Games
682
Lane
Mid
Tier
All Tiers
Last Updated
Oct 11, 2026 UTC
Methodology
Data Methodology

Best Mid Anivia runes for LoL Patch 26.20 - Electrocute from the Domination tree with Sorcery secondary (55.6% WR, 20.8% pick rate). Anivia's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Secondary tree: Manaflow Band, Scorch.

Anivia performs best with Electrocute as the keystone rune from the Domination tree. Anivia's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Anivia's secondary rune tree is Sorcery with Manaflow Band, Scorch. This rune setup achieves a 55.63% win rate (+1.4% win rate difference) with a 20.8% pick rate across 142 Anivia games.
55.6%Win Rate
+1.4%WR Diff
20.8%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

This alternative Anivia rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Anivia's secondary rune tree is Precision with Presence of Mind, Coup de Grace. This setup achieves a 55.77% win rate (+1.5% win rate difference) with a 7.6% pick rate across 52 games.
55.8%Win Rate
+1.5%WR Diff
7.6%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Presence of MindPresence of Mind

Damaging an enemy champion restores 6-50 (80% for ranged) mana or 6 energy.

Takedowns restore 15% of your maximum mana or energy.

Cooldown for damage restoration: 8s

Coup de GraceCoup de Grace

Deal 8% more damage to champions who have less than 40% health.

These champions share at least 4 runes with Anivia's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Anivia's playstyle or want to learn champions with familiar rune setups.Katarina, Zoe, LeBlanc, Gragas, Naafiri and 4 others

Every Anivia Mid Keystone and Secondary Tree (Patch 26.20)

670 games

Anivia Mid runs Electrocute in 73% of games, with a 54.5% win rate. Precision is the usual secondary tree (65%). Standard stat shards: Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
ElectrocuteElectrocuteMost played72.5%54.5%486
Arcane CometArcane Comet13.7%51.1%92
Deathfire TouchDeathfire Touch9.6%57.8%64

Secondary trees

RunePlayersWin RateGames
PrecisionPrecisionMost played64.6%54.7%433
SorcerySorcery29.4%52.3%197

Pick rate is the share of Anivia games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Anivia Minor Runes by Tree

Every minor rune Anivia players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Cheap ShotCheap ShotMost played72.2%54.5%484
Relentless HunterRelentless Hunter67.2%54.2%450
Grisly MementosGrisly Mementos60.7%53.3%407
Sixth SenseSixth Sense7.3%55.1%49

Precision

RunePlayersWin RateGames
Presence of MindPresence of MindMost played63.0%54.3%422
Coup de GraceCoup de Grace49.1%52.9%329
Cut DownCut Down13.4%57.8%90

Sorcery

RunePlayersWin RateGames
Manaflow BandManaflow BandMost played51.9%53.4%348
ScorchScorch43.6%50.3%292
TranscendenceTranscendence21.3%51.0%143
Gathering StormGathering Storm9.0%65.0%60

Anivia Stat Shards

Which stat shards Anivia players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played90.6%53.0%607
Health Scaling (defense)Health Scaling (defense)80.3%53.2%538
Attack Speed (offense)Attack Speed (offense)74.0%54.0%496
Adaptive Force (offense)Adaptive Force (offense)22.2%51.0%149
Health (defense)Health (defense)15.4%55.3%103
Move Speed (flex)Move Speed (flex)7.3%65.3%49
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Anivia Runes FAQ - Patch 26.20

What is the best keystone for Anivia Mid?

Electrocute: Anivia Mid takes it in 73% of ranked games and wins 54.5% of 486 games. Alternatives: Arcane Comet (14%, 51.1%), Deathfire Touch (10%, 57.8%).

What stat shards should Anivia take?

Most Anivia players take Attack Speed (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Anivia runes in patch 26.20?

The best Anivia runes in patch 26.20 use the Domination tree with Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, and the Sorcery tree with Manaflow Band and Scorch. This rune setup achieves a 55.6% win rate with a 20.8% pick rate.

What is the win rate for Anivia's best rune page?

Anivia's best rune page has a 55.6% win rate in patch 26.20, which is +1.4% compared to Anivia's average win rate. This rune setup has a 20.8% pick rate among Anivia players.

What keystone should I use on Anivia?

Electrocute from the Domination tree is the best keystone rune for Anivia in patch 26.20. This keystone synergizes well with Anivia's kit and provides a 55.6% win rate.

What is Anivia's primary rune tree?

Anivia's primary rune tree is Domination. The optimal Domination runes for Anivia are Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Anivia's secondary rune tree?

Anivia's best secondary rune tree is Sorcery. The recommended Sorcery runes are Manaflow Band and Scorch, which complement Anivia's Domination primary tree.

What are alternative rune setups for Anivia?

An alternative Anivia rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Anivia's runes?

Anivia's top rune page has a 20.8% pick rate in patch 26.20. This indicates that 20.8% of Anivia players use the Electrocute setup with Domination and Sorcery trees.