Cassiopeiavs Seraphine
Cassiopeia vs Seraphine is a decisive matchup in LoL patch 26.14. Cassiopeia wins with a 77.8% win rate (+55.6%) over Seraphine based on 9 games. Cassiopeia holds the advantage in both the early and late game. Below you'll find the best Cassiopeia build, runes, laning stats, and strategies for the Cassiopeia vs Seraphine matchup.
Cassiopeia Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Cassiopeia performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Cassiopeia vs Seraphine Matchup?
Cassiopeia vs Seraphine Matchup Summary
The Cassiopeia vs Seraphine matchup is a decisive matchup in League of Legends ranked play. Based on 9 recent matches analyzed, Cassiopeia wins with a 77.8% win rate compared to Seraphine's 22.2%, giving Cassiopeia a 55.6 percentage point advantage. Cassiopeia dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 324 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Cassiopeia players can confidently pick into Seraphine and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Seraphine away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Cassiopeia vs Seraphine Laning Phase Breakdown
Cassiopeia is favored during the laning phase against Seraphine, winning 5 out of 5 key stat categories. Cassiopeia holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.
Best Cassiopeia Build Against Seraphine
Swiftmarch is the optimal boots choice against Seraphine, providing the mobility and stats Cassiopeia needs most in this matchup. The top-performing core items for Cassiopeia against Seraphine are Rod of Ages, Liandry's Torment and Seraph's Embrace. This combination gives Cassiopeia an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Seraphine. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Cassiopeia vs Seraphine matchup.
Early Game vs Late Game
Cassiopeia100.0%
Seraphine0.0%Cassiopeia71.4%Seraphine28.6%Cassiopeia dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Seraphine. This lopsided early game means Cassiopeia can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Cassiopeia is far superior in the late game (25+ minutes), boasting a 71.4% win rate — 42.9 points above Seraphine. Extended games heavily favor Cassiopeia, whose kit and scaling make them a dominant force in team fights and objective control.
Cassiopeia holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Cassiopeia Runes Against Seraphine
Precision
Sorcery
Running Precision primary with Sorcery secondary allows Cassiopeia to press their advantage against Seraphine, amplifying the strengths that make this a favorable matchup.
Cassiopeia matchup data for League of Legends patch 26.14. The table below shows Cassiopeia's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Cassiopeia build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 43.24% | 37 | 6.6 | 877 | 10,505 | 26.7% | 54.5% | |
| 50.00% | 30 | 5.9 | 865 | 10,458 | 45.5% | 52.6% | |
| 46.67% | 30 | 6.5 | 766 | 10,531 | 42.9% | 50.0% | |
| 48.28% | 29 | 6.5 | 964 | 11,073 | 56.3% | 38.5% | |
| 29.63% | 27 | 6.5 | 842 | 11,427 | 27.3% | 31.3% | |
| 56.52% | 23 | 5.5 | 650 | 10,054 | 40.0% | 69.2% | |
| 54.55% | 22 | 6.3 | 717 | 10,752 | 33.3% | 69.2% | |
| 66.67% | 21 | 6.3 | 793 | 9,592 | 77.8% | 58.3% | |
| 77.78% | 18 | 6.4 | 832 | 12,098 | 87.5% | 70.0% | |
| 41.18% | 17 | 6.2 | 859 | 10,987 | 0.0% | 63.6% | |
| 47.06% | 17 | 6.8 | 916 | 10,673 | 33.3% | 62.5% | |
| 58.82% | 17 | 6.8 | 883 | 11,902 | 50.0% | 66.7% | |
| 58.82% | 17 | 6.5 | 862 | 11,859 | 57.1% | 60.0% | |
| 41.18% | 17 | 6.1 | 696 | 10,424 | 14.3% | 60.0% | |
| 68.75% | 16 | 6.6 | 725 | 12,820 | 100.0% | 61.5% | |
| 25.00% | 16 | 6.6 | 644 | 10,619 | 22.2% | 28.6% | |
| 60.00% | 15 | 6.7 | 864 | 12,061 | 80.0% | 50.0% | |
| 28.57% | 14 | 5.2 | 947 | 11,215 | 20.0% | 33.3% | |
| 64.29% | 14 | 6.3 | 937 | 15,587 | 100.0% | 58.3% | |
| 30.77% | 13 | 7.2 | 660 | 10,238 | 33.3% | 28.6% | |
| 46.15% | 13 | 6.3 | 887 | 11,898 | 60.0% | 37.5% | |
| 38.46% | 13 | 6.0 | 749 | 11,493 | 25.0% | 44.4% | |
| 58.33% | 12 | 6.0 | 791 | 10,354 | 66.7% | 50.0% | |
| 18.18% | 11 | 6.4 | 816 | 13,124 | 0.0% | 20.0% | |
| 36.36% | 11 | 6.5 | 795 | 11,106 | 20.0% | 50.0% | |
| 45.45% | 11 | 6.4 | 698 | 11,236 | 60.0% | 33.3% | |
| 20.00% | 10 | 6.4 | 710 | 10,022 | 20.0% | 20.0% | |
| 77.78% | 9 | 6.1 | 969 | 12,632 | 66.7% | 83.3% | |
| 22.22% | 9 | 6.0 | 954 | 14,954 | 0.0% | 28.6% | |
| 77.78% | 9 | 7.0 | 835 | 8,421 | 85.7% | 50.0% | |
| 44.44% | 9 | 6.5 | 930 | 12,248 | 66.7% | 33.3% | |
| 66.67% | 9 | 6.8 | 1,033 | 12,455 | 66.7% | 66.7% | |
| 77.78% | 9 | 6.0 | 864 | 13,088 | 100.0% | 71.4% | |
| 37.50% | 8 | 6.6 | 965 | 14,894 | 33.3% | 40.0% | |
| 37.50% | 8 | 6.4 | 739 | 11,899 | 50.0% | 33.3% | |
| 57.14% | 7 | 7.4 | 1,131 | 11,888 | 100.0% | 40.0% | |
| 71.43% | 7 | 6.8 | 910 | 11,391 | 75.0% | 66.7% | |
| 42.86% | 7 | 6.7 | 910 | 11,030 | 33.3% | 50.0% | |
| 42.86% | 7 | 5.2 | 618 | 8,805 | 25.0% | 66.7% | |
| 42.86% | 7 | 7.2 | 974 | 13,071 | 0.0% | 75.0% | |
| 85.71% | 7 | 6.4 | 929 | 14,882 | 50.0% | 100.0% | |
| 0.00% | 7 | 5.9 | 643 | 9,853 | 0.0% | 0.0% | |
| 42.86% | 7 | 6.3 | 851 | 10,539 | 0.0% | 75.0% | |
| 85.71% | 7 | 6.8 | 1,021 | 12,042 | 100.0% | 66.7% | |
| 42.86% | 7 | 6.4 | 833 | 11,762 | 33.3% | 50.0% | |
| 57.14% | 7 | 6.3 | 900 | 8,838 | 66.7% | 50.0% | |
| 42.86% | 7 | 7.7 | 735 | 10,618 | 50.0% | 33.3% | |
| 57.14% | 7 | 5.6 | 864 | 9,854 | 100.0% | 0.0% | |
| 42.86% | 7 | 6.2 | 703 | 12,072 | 50.0% | 40.0% | |
| 57.14% | 7 | 6.7 | 776 | 9,868 | 75.0% | 33.3% | |
| 33.33% | 6 | 6.1 | 729 | 9,176 | 0.0% | 50.0% | |
| 16.67% | 6 | 4.8 | 717 | 11,929 | 0.0% | 20.0% | |
| 33.33% | 6 | 6.2 | 648 | 8,582 | 66.7% | 0.0% | |
| 33.33% | 6 | 6.3 | 598 | 8,920 | 25.0% | 50.0% | |
| 50.00% | 6 | 6.6 | 947 | 13,805 | 50.0% | 50.0% | |
| 16.67% | 6 | 6.0 | 712 | 9,879 | 33.3% | 0.0% | |
| 50.00% | 6 | 6.0 | 834 | 12,882 | 0.0% | 75.0% | |
| 33.33% | 6 | 6.4 | 952 | 13,204 | 0.0% | 40.0% | |
| 50.00% | 6 | 7.2 | 1,092 | 9,784 | 25.0% | 100.0% | |
| 20.00% | 5 | 6.0 | 720 | 10,789 | 0.0% | 33.3% | |
| 60.00% | 5 | 7.2 | 1,062 | 12,030 | 50.0% | 66.7% | |
| 40.00% | 5 | 6.5 | 692 | 12,201 | 50.0% | 33.3% | |
| 80.00% | 5 | 8.2 | 930 | 11,461 | 100.0% | 50.0% | |
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Cassiopeia vs Seraphine - Frequently Asked Questions
How does Cassiopeia do against Seraphine in League of Legends?
Cassiopeia wins the Cassiopeia vs Seraphine matchup with a 77.8% win rate compared to Seraphine's 22.2%, a 55.6 percentage point difference. This data is based on 9 recent ranked games in patch 26.14.
How does Cassiopeia do against Seraphine in the early game?
In the early game, Cassiopeia has the advantage against Seraphine with a 100.0% win rate versus 0.0%. Cassiopeia players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Cassiopeia do against Seraphine in the late game?
In the late game, Cassiopeia takes over the Cassiopeia vs Seraphine matchup with a 71.4% win rate compared to 28.6%. Cassiopeia scales better into team fights and objective contests after 25 minutes.
Who wins the Cassiopeia vs Seraphine matchup?
Cassiopeia wins the matchup against Seraphine with a 77.8% win rate in League of Legends patch 26.14. The 55.6 percentage point advantage means Cassiopeia is significantly favored in this lane matchup based on 9 games analyzed.
What is the best Cassiopeia build against Seraphine?
The best Cassiopeia build against Seraphine includes Rod of Ages, Liandry's Torment, Seraph's Embrace with Swiftmarch. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Cassiopeia runes against Seraphine?
The best Cassiopeia runes against Seraphine use the Precision primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Cassiopeia vs Seraphine matchup. See the full rune breakdown in the matchup comparison above.
Does Cassiopeia counter Seraphine?
Yes, Cassiopeia has a favorable matchup against Seraphine with a 77.8% win rate. Cassiopeia strongly counters Seraphine in lane based on current patch 26.14 data.
How do I play Cassiopeia against Seraphine?
When playing Cassiopeia against Seraphine, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.