
Seraphinevs Cassiopeia
Seraphine vs Cassiopeia is a decisive matchup in LoL patch 26.9. Seraphine wins with a 66.7% win rate (+33.3%) over Cassiopeia based on 6 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Cassiopeia matchup.
Seraphine Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Seraphine vs Cassiopeia Matchup?

Seraphine vs Cassiopeia Matchup Summary
The Seraphine vs Cassiopeia matchup is a decisive matchup in League of Legends ranked play. Based on 6 recent matches analyzed, Seraphine wins with a 66.7% win rate compared to Cassiopeia's 33.3%, giving Seraphine a 33.3 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Cassiopeia players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Cassiopeia leads by 348 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Cassiopeia and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Cassiopeia away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Seraphine vs Cassiopeia Laning Phase Breakdown
Seraphine is favored during the laning phase against Cassiopeia, winning 4 out of 5 key stat categories. Seraphine holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.
Best Seraphine Build Against Cassiopeia
Spellslinger's Shoes is the optimal boots choice against Cassiopeia, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Cassiopeia are Luden's Echo, Stormsurge and Rabadon's Deathcap. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Cassiopeia. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Cassiopeia matchup.
Early Game vs Late Game
Seraphine dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Cassiopeia. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Seraphine is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Cassiopeia. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.
Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Cassiopeia players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Seraphine Runes Against Cassiopeia
Running Sorcery primary with Precision secondary allows Seraphine to press their advantage against Cassiopeia, amplifying the strengths that make this a favorable matchup.
Seraphine matchup data for League of Legends patch 26.9. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 54.32% | 440 | 1.6 | 447 | 9,389 | 52.5% | 55.6% | |
| 51.11% | 407 | 1.3 | 455 | 8,697 | 53.1% | 49.3% | |
| 52.82% | 354 | 1.4 | 491 | 9,452 | 48.9% | 55.4% | |
| 47.26% | 292 | 1.4 | 498 | 9,160 | 50.7% | 44.2% | |
| 51.52% | 264 | 1.7 | 537 | 9,659 | 55.4% | 48.7% | |
| 53.67% | 259 | 1.6 | 489 | 9,040 | 58.3% | 50.0% | |
| 48.63% | 255 | 1.7 | 506 | 9,416 | 37.5% | 56.3% | |
| 54.29% | 246 | 1.5 | 507 | 9,555 | 58.8% | 51.4% | |
| 55.74% | 235 | 1.3 | 486 | 8,829 | 63.1% | 49.2% | |
| 51.63% | 215 | 1.4 | 497 | 8,688 | 52.2% | 51.0% | |
| 49.00% | 200 | 1.4 | 433 | 8,603 | 47.1% | 51.0% | |
| 50.28% | 181 | 1.5 | 499 | 9,426 | 48.1% | 52.0% | |
| 50.85% | 177 | 1.4 | 535 | 8,961 | 51.8% | 50.0% | |
| 54.86% | 175 | 1.3 | 415 | 9,000 | 58.0% | 52.8% | |
| 58.14% | 172 | 1.4 | 463 | 9,416 | 53.7% | 61.0% | |
| 56.02% | 166 | 1.4 | 502 | 9,146 | 64.9% | 48.9% | |
| 55.92% | 152 | 1.4 | 368 | 8,417 | 63.5% | 48.7% | |
| 51.37% | 146 | 1.4 | 497 | 9,420 | 52.9% | 50.0% | |
| 53.15% | 143 | 1.7 | 552 | 9,434 | 56.9% | 50.6% | |
| 56.20% | 137 | 1.5 | 480 | 9,719 | 56.7% | 55.8% | |
| 53.68% | 136 | 1.4 | 452 | 8,736 | 56.9% | 50.0% | |
| 53.03% | 132 | 1.4 | 617 | 9,197 | 52.5% | 53.5% | |
| 56.88% | 110 | 2.1 | 507 | 10,220 | 54.5% | 57.9% | |
| 55.56% | 108 | 1.4 | 498 | 9,246 | 59.5% | 53.0% | |
| 52.48% | 101 | 1.8 | 472 | 9,414 | 46.3% | 56.7% | |
| 56.38% | 94 | 1.4 | 451 | 8,689 | 57.5% | 55.3% | |
| 54.02% | 87 | 1.3 | 530 | 8,428 | 68.3% | 41.3% | |
| 50.60% | 84 | 1.4 | 500 | 9,090 | 70.0% | 39.6% | |
| 56.25% | 80 | 4.7 | 622 | 10,645 | 55.0% | 57.5% | |
| 46.67% | 75 | 1.4 | 483 | 9,013 | 52.6% | 40.5% | |
| 54.29% | 70 | 1.4 | 488 | 9,237 | 54.8% | 53.9% | |
| 55.07% | 69 | 1.4 | 482 | 9,984 | 60.9% | 52.2% | |
| 48.33% | 60 | 6.6 | 719 | 12,709 | 42.9% | 51.3% | |
| 48.28% | 58 | 1.5 | 530 | 8,800 | 46.9% | 50.0% | |
| 48.21% | 56 | 6.5 | 831 | 12,453 | 55.0% | 44.4% | |
| 50.00% | 56 | 5.9 | 783 | 12,078 | 44.0% | 54.8% | |
| 44.90% | 49 | 1.4 | 519 | 8,763 | 44.0% | 45.8% | |
| 55.10% | 49 | 5.8 | 723 | 12,000 | 66.7% | 50.0% | |
| 61.70% | 47 | 1.4 | 476 | 9,162 | 61.9% | 61.5% | |
| 56.41% | 39 | 2.0 | 587 | 10,648 | 66.7% | 50.0% | |
| 57.89% | 38 | 5.1 | 710 | 11,816 | 53.9% | 60.0% | |
| 47.37% | 38 | 2.2 | 579 | 9,659 | 64.7% | 33.3% | |
| 71.43% | 35 | 6.7 | 836 | 13,166 | 72.2% | 70.6% | |
| 58.82% | 34 | 4.4 | 669 | 10,693 | 64.3% | 55.0% | |
| 43.75% | 32 | 1.2 | 415 | 8,492 | 50.0% | 37.5% | |
| 41.94% | 31 | 1.3 | 428 | 9,521 | 36.4% | 45.0% | |
| 67.86% | 28 | 4.4 | 701 | 12,078 | 90.0% | 55.6% | |
| 61.54% | 26 | 3.8 | 597 | 9,693 | 75.0% | 50.0% | |
| 56.00% | 25 | 5.7 | 743 | 10,806 | 42.9% | 61.1% | |
| 40.00% | 25 | 1.3 | 469 | 8,454 | 50.0% | 30.8% | |
| 58.33% | 24 | 2.2 | 489 | 10,011 | 62.5% | 56.3% | |
| 33.33% | 24 | 2.0 | 483 | 8,861 | 33.3% | 33.3% | |
| 52.17% | 23 | 3.2 | 608 | 8,977 | 66.7% | 36.4% | |
| 52.17% | 23 | 1.6 | 487 | 9,685 | 44.4% | 57.1% | |
| 47.83% | 23 | 6.4 | 784 | 12,486 | 57.1% | 33.3% | |
| 60.87% | 23 | 1.7 | 517 | 9,789 | 60.0% | 61.5% | |
| 50.00% | 22 | 1.4 | 522 | 8,487 | 60.0% | 41.7% | |
| 57.14% | 21 | 6.6 | 730 | 11,710 | 44.4% | 66.7% | |
| 45.00% | 20 | 5.9 | 817 | 13,007 | 75.0% | 37.5% | |
| 45.00% | 20 | 1.6 | 546 | 9,728 | 50.0% | 42.9% | |
| 47.37% | 19 | 5.0 | 681 | 10,459 | 44.4% | 50.0% | |
| 73.68% | 19 | 6.0 | 796 | 11,369 | 87.5% | 63.6% | |
| 66.67% | 18 | 1.9 | 477 | 10,176 | 71.4% | 63.6% | |
| 44.44% | 18 | 6.1 | 781 | 11,827 | 50.0% | 37.5% | |
| 47.06% | 17 | 1.4 | 556 | 9,908 | 62.5% | 33.3% | |
| 60.00% | 15 | 1.5 | 505 | 9,689 | 85.7% | 37.5% | |
| 50.00% | 14 | 6.0 | 822 | 12,565 | 66.7% | 37.5% | |
| 71.43% | 14 | 3.8 | 566 | 10,907 | 80.0% | 66.7% | |
| 61.54% | 13 | 7.1 | 767 | 12,833 | 60.0% | 62.5% | |
| 38.46% | 13 | 4.7 | 756 | 11,441 | 40.0% | 37.5% | |
| 69.23% | 13 | 2.1 | 474 | 11,370 | 100.0% | 42.9% | |
| 33.33% | 12 | 5.6 | 750 | 8,386 | 37.5% | 25.0% | |
| 50.00% | 12 | 4.1 | 665 | 10,631 | 50.0% | 50.0% | |
| 66.67% | 12 | 1.3 | 399 | 6,712 | 55.6% | 100.0% | |
| 75.00% | 12 | 6.7 | 812 | 11,795 | 62.5% | 100.0% | |
| 45.45% | 11 | 6.5 | 587 | 10,428 | 80.0% | 16.7% | |
| 72.73% | 11 | 5.3 | 982 | 12,255 | 60.0% | 83.3% | |
| 54.55% | 11 | 6.5 | 889 | 12,674 | 40.0% | 66.7% | |
| 72.73% | 11 | 4.9 | 764 | 11,341 | 66.7% | 80.0% | |
| 63.64% | 11 | 1.9 | 547 | 9,806 | 50.0% | 71.4% | |
| 81.82% | 11 | 4.2 | 642 | 11,181 | 100.0% | 75.0% | |
| 50.00% | 10 | 1.8 | 437 | 8,637 | 57.1% | 33.3% | |
| 100.00% | 9 | 1.6 | 512 | 11,283 | 100.0% | 100.0% | |
| 44.44% | 9 | 1.4 | 489 | 9,816 | 0.0% | 66.7% | |
| 55.56% | 9 | 6.5 | 825 | 12,183 | 33.3% | 66.7% | |
| 66.67% | 9 | 3.9 | 497 | 8,874 | 71.4% | 50.0% | |
| 66.67% | 9 | 4.7 | 863 | 11,676 | 50.0% | 71.4% | |
| 33.33% | 9 | 1.4 | 333 | 9,266 | 33.3% | 33.3% | |
| 66.67% | 9 | 5.0 | 713 | 10,101 | 60.0% | 75.0% | |
| 62.50% | 8 | 2.1 | 593 | 11,482 | 100.0% | 57.1% | |
| 37.50% | 8 | 3.8 | 746 | 10,746 | 50.0% | 25.0% | |
| 37.50% | 8 | 4.0 | 653 | 10,092 | 40.0% | 33.3% | |
| 50.00% | 8 | 5.8 | 663 | 9,687 | 50.0% | 50.0% | |
| 50.00% | 8 | 4.1 | 627 | 13,263 | 75.0% | 25.0% | |
| 28.57% | 7 | 4.9 | 560 | 9,457 | 20.0% | 50.0% | |
| 42.86% | 7 | 5.2 | 753 | 9,534 | 50.0% | 33.3% | |
| 42.86% | 7 | 6.8 | 717 | 11,985 | 50.0% | 40.0% | |
| 14.29% | 7 | 2.9 | 603 | 11,038 | 0.0% | 20.0% | |
| 85.71% | 7 | 4.0 | 662 | 11,827 | 0.0% | 100.0% | |
| 28.57% | 7 | 3.0 | 611 | 11,009 | 100.0% | 0.0% | |
| 28.57% | 7 | 2.0 | 514 | 7,602 | 20.0% | 50.0% | |
| 50.00% | 6 | 2.7 | 490 | 10,853 | 33.3% | 66.7% | |
| 50.00% | 6 | 4.9 | 738 | 10,969 | 33.3% | 66.7% | |
| 66.67% | 6 | 6.5 | 781 | 12,937 | 100.0% | 60.0% | |
| 50.00% | 6 | 7.2 | 754 | 9,659 | 25.0% | 100.0% | |
| 66.67% | 6 | 6.0 | 710 | 10,291 | 100.0% | 33.3% | |
| 50.00% | 6 | 5.8 | 494 | 10,234 | 0.0% | 75.0% | |
| 66.67% | 6 | 3.3 | 542 | 11,455 | 100.0% | 60.0% | |
| 50.00% | 6 | 5.9 | 759 | 12,386 | 0.0% | 60.0% | |
| 60.00% | 5 | 2.0 | 862 | 9,093 | 50.0% | 66.7% | |
| 40.00% | 5 | 7.1 | 803 | 9,913 | 33.3% | 50.0% | |
| 100.00% | 5 | 1.2 | 608 | 8,052 | 100.0% | 100.0% | |
| 80.00% | 5 | 6.2 | 751 | 9,814 | 66.7% | 100.0% | |
| 0.00% | 5 | 3.4 | 709 | 12,118 | 0.0% | 0.0% | |
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Seraphine vs Cassiopeia - Frequently Asked Questions
How does Seraphine do against Cassiopeia in League of Legends?
Seraphine wins the Seraphine vs Cassiopeia matchup with a 66.7% win rate compared to Cassiopeia's 33.3%, a 33.3 percentage point difference. This data is based on 6 recent ranked games in patch 26.9.
How does Seraphine do against Cassiopeia in the early game?
In the early game, Seraphine has the advantage against Cassiopeia with a 100.0% win rate versus 0.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Seraphine do against Cassiopeia in the late game?
In the late game, Seraphine takes over the Seraphine vs Cassiopeia matchup with a 60.0% win rate compared to 40.0%. Seraphine scales better into team fights and objective contests after 25 minutes.
Who wins the Seraphine vs Cassiopeia matchup?
Seraphine wins the matchup against Cassiopeia with a 66.7% win rate in League of Legends patch 26.9. The 33.3 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 6 games analyzed.
What is the best Seraphine build against Cassiopeia?
The best Seraphine build against Cassiopeia includes Luden's Echo, Stormsurge, Rabadon's Deathcap with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.
What are the best Seraphine runes against Cassiopeia?
The best Seraphine runes against Cassiopeia use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Cassiopeia matchup. See the full rune breakdown in the matchup comparison above.
Does Seraphine counter Cassiopeia?
Yes, Seraphine has a favorable matchup against Cassiopeia with a 66.7% win rate. Seraphine strongly counters Cassiopeia in lane based on current patch 26.9 data.
How do I play Seraphine against Cassiopeia?
When playing Seraphine against Cassiopeia, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.
