Seraphine - League of Legends Champion
Win Rate
52.7%
Pick Rate
7.0%

Seraphinevs Zeri

SSupportMage
Patch26.9
Matches514,344
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 9, 2026
MethodologyData Methodology

Seraphine vs Zeri is a decisive matchup in LoL patch 26.9. Zeri wins with a 57.1% win rate (+14.3%) over Seraphine based on 7 games. Seraphine wins the early laning phase while Zeri scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Zeri matchup.

Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Zeri - 42.9% win rateZeri(42.9%)
Seraphine - 42.9% win rate in this matchup
Seraphine
42.9% WR
VS
Zeri vs Seraphine matchup - 57.1% win rate
Zeri
57.1% WR

Who Wins the Seraphine vs Zeri Matchup?

Zeri wins the Seraphine vs Zeri matchup
Winner
Zeri
Matches: 7
42.9%
Win Rate
57.1%
6.8
CS / min
7.9
717
DMG / min
867
11,985
Gold / game
13,649
483
Heal / min
191
478
DMG Mitigated / min
385
0.9
CC / min
0.2
50.0%
Early Game WR
50.0%
40.0%
Late Game WR
60.0%

Seraphine vs Zeri Matchup Summary

The Seraphine vs Zeri matchup is a decisive matchup in League of Legends ranked play. Based on 7 recent matches analyzed, Zeri wins with a 57.1% win rate compared to Seraphine's 42.9%, giving Zeri a 14.3 percentage point advantage. Game phase dynamics play a critical role here: Seraphine controls the early laning stage, but Zeri outscales as the game goes longer. The matchup shifts dramatically depending on game length — Seraphine needs to press advantages before Zeri reaches their power spikes, while Zeri should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Seraphine leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Zeri has a strong advantage in this matchup. Seraphine players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Zeri overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Zeri Laning Phase Breakdown

Zeri wins the laning phase against Seraphine in League of Legends

Zeri is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Zeri holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.

Farming
6.8Seraphine
7.9Zeri
Zeri significantly out-farms Seraphine by 1.1 CS per minute, accumulating an estimated 17 CS lead by mid game. This substantial farming gap gives Zeri a major gold advantage and earlier item completions. Seraphine players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
717Seraphine
867Zeri
Zeri heavily out-damages Seraphine by 150 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Zeri's sustained damage advantage take over.
Economy
11,985Seraphine
13,649Zeri
Zeri generates a commanding 1,664 more gold per game than Seraphine. This substantial economic advantage means Zeri consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Seraphine should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
0.9Seraphine
0.2Zeri
Seraphine provides 0.7 seconds more crowd control per minute than Zeri, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Seraphine coordinate with their jungler and control the pace of skirmishes.
Sustain
961Seraphine
576Zeri
Seraphine vastly out-sustains Zeri, healing and mitigating 385 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Zeri is forced to recall. Building grievous wounds early is essential for Zeri, and focusing on burst trade patterns rather than sustained fights is critical.

Early Game vs Late Game

Early Game
Seraphine
50.0%
+0.0% advantage
Seraphine early game win rateSeraphine50.0%
Zeri early game win rateZeri50.0%
Late Game
Zeri
60.0%
+20.0% advantage
Seraphine late game win rateSeraphine40.0%
Zeri late game win rateZeri60.0%

The early game (first 15 minutes) is a toss-up between Seraphine and Zeri, with Seraphine holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Zeri is far superior in the late game (25+ minutes), boasting a 60.0% win rate — 20.0 points above Seraphine. Extended games heavily favor Zeri, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Seraphine has the edge early, but Zeri gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Seraphine Runes Against Zeri

Sorcery rune tree - Seraphine primary runes vs ZeriSorcery
Arcane Comet - best Seraphine rune vs ZeriManaflow Band - best Seraphine rune vs ZeriTranscendence - best Seraphine rune vs ZeriGathering Storm - best Seraphine rune vs Zeri
Inspiration rune tree - Seraphine secondary runes vs ZeriInspiration
Cash Back - best Seraphine rune vs ZeriTriple Tonic - best Seraphine rune vs Zeri
100.0% WR

The Sorcery and Inspiration rune setup gives Seraphine the best tools to compete against Zeri in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.9. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.9
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
54.32%4401.64479,38952.5%55.6%
51.11%4071.34558,69753.1%49.3%
52.82%3541.44919,45248.9%55.4%
47.26%2921.44989,16050.7%44.2%
51.52%2641.75379,65955.4%48.7%
53.67%2591.64899,04058.3%50.0%
48.63%2551.75069,41637.5%56.3%
54.29%2461.55079,55558.8%51.4%
55.74%2351.34868,82963.1%49.2%
51.63%2151.44978,68852.2%51.0%
49.00%2001.44338,60347.1%51.0%
50.28%1811.54999,42648.1%52.0%
50.85%1771.45358,96151.8%50.0%
54.86%1751.34159,00058.0%52.8%
58.14%1721.44639,41653.7%61.0%
56.02%1661.45029,14664.9%48.9%
55.92%1521.43688,41763.5%48.7%
51.37%1461.44979,42052.9%50.0%
53.15%1431.75529,43456.9%50.6%
56.20%1371.54809,71956.7%55.8%
53.68%1361.44528,73656.9%50.0%
53.03%1321.46179,19752.5%53.5%
56.88%1102.150710,22054.5%57.9%
55.56%1081.44989,24659.5%53.0%
52.48%1011.84729,41446.3%56.7%
56.38%941.44518,68957.5%55.3%
54.02%871.35308,42868.3%41.3%
50.60%841.45009,09070.0%39.6%
56.25%804.762210,64555.0%57.5%
46.67%751.44839,01352.6%40.5%
54.29%701.44889,23754.8%53.9%
55.07%691.44829,98460.9%52.2%
48.33%606.671912,70942.9%51.3%
48.28%581.55308,80046.9%50.0%
48.21%566.583112,45355.0%44.4%
50.00%565.978312,07844.0%54.8%
44.90%491.45198,76344.0%45.8%
55.10%495.872312,00066.7%50.0%
61.70%471.44769,16261.9%61.5%
56.41%392.058710,64866.7%50.0%
57.89%385.171011,81653.9%60.0%
47.37%382.25799,65964.7%33.3%
71.43%356.783613,16672.2%70.6%
58.82%344.466910,69364.3%55.0%
43.75%321.24158,49250.0%37.5%
41.94%311.34289,52136.4%45.0%
67.86%284.470112,07890.0%55.6%
61.54%263.85979,69375.0%50.0%
56.00%255.774310,80642.9%61.1%
40.00%251.34698,45450.0%30.8%
58.33%242.248910,01162.5%56.3%
33.33%242.04838,86133.3%33.3%
52.17%233.26088,97766.7%36.4%
52.17%231.64879,68544.4%57.1%
47.83%236.478412,48657.1%33.3%
60.87%231.75179,78960.0%61.5%
50.00%221.45228,48760.0%41.7%
57.14%216.673011,71044.4%66.7%
45.00%205.981713,00775.0%37.5%
45.00%201.65469,72850.0%42.9%
47.37%195.068110,45944.4%50.0%
73.68%196.079611,36987.5%63.6%
66.67%181.947710,17671.4%63.6%
44.44%186.178111,82750.0%37.5%
47.06%171.45569,90862.5%33.3%
60.00%151.55059,68985.7%37.5%
50.00%146.082212,56566.7%37.5%
71.43%143.856610,90780.0%66.7%
61.54%137.176712,83360.0%62.5%
38.46%134.775611,44140.0%37.5%
69.23%132.147411,370100.0%42.9%
33.33%125.67508,38637.5%25.0%
50.00%124.166510,63150.0%50.0%
66.67%121.33996,71255.6%100.0%
75.00%126.781211,79562.5%100.0%
45.45%116.558710,42880.0%16.7%
72.73%115.398212,25560.0%83.3%
54.55%116.588912,67440.0%66.7%
72.73%114.976411,34166.7%80.0%
63.64%111.95479,80650.0%71.4%
81.82%114.264211,181100.0%75.0%
50.00%101.84378,63757.1%33.3%
100.00%91.651211,283100.0%100.0%
44.44%91.44899,8160.0%66.7%
55.56%96.582512,18333.3%66.7%
66.67%93.94978,87471.4%50.0%
66.67%94.786311,67650.0%71.4%
33.33%91.43339,26633.3%33.3%
66.67%95.071310,10160.0%75.0%
62.50%82.159311,482100.0%57.1%
37.50%83.874610,74650.0%25.0%
37.50%84.065310,09240.0%33.3%
50.00%85.86639,68750.0%50.0%
50.00%84.162713,26375.0%25.0%
28.57%74.95609,45720.0%50.0%
42.86%75.27539,53450.0%33.3%
42.86%76.871711,98550.0%40.0%
14.29%72.960311,0380.0%20.0%
85.71%74.066211,8270.0%100.0%
28.57%73.061111,009100.0%0.0%
28.57%72.05147,60220.0%50.0%
50.00%62.749010,85333.3%66.7%
50.00%64.973810,96933.3%66.7%
66.67%66.578112,937100.0%60.0%
50.00%67.27549,65925.0%100.0%
66.67%66.071010,291100.0%33.3%
50.00%65.849410,2340.0%75.0%
66.67%63.354211,455100.0%60.0%
50.00%65.975912,3860.0%60.0%
60.00%52.08629,09350.0%66.7%
40.00%57.18039,91333.3%50.0%
100.00%51.26088,052100.0%100.0%
80.00%56.27519,81466.7%100.0%
0.00%53.470912,1180.0%0.0%

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Seraphine vs Zeri - Frequently Asked Questions

How does Seraphine do against Zeri in League of Legends?

Zeri wins the Seraphine vs Zeri matchup with a 57.1% win rate compared to Seraphine's 42.9%, a 14.3 percentage point difference. This data is based on 7 recent ranked games in patch 26.9.

How does Seraphine do against Zeri in the early game?

In the early game, Seraphine has the advantage against Zeri with a 50.0% win rate versus 50.0%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Zeri in the late game?

In the late game, Zeri takes over the Seraphine vs Zeri matchup with a 60.0% win rate compared to 40.0%. Zeri scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Zeri matchup?

Zeri wins the matchup against Seraphine with a 57.1% win rate in League of Legends patch 26.9. The 14.3 percentage point advantage means Zeri is significantly favored in this lane matchup based on 7 games analyzed.

What is the best Seraphine build against Zeri?

The best Seraphine build against Zeri includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Zeri?

The best Seraphine runes against Zeri use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Seraphine vs Zeri matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Zeri?

No, Seraphine struggles against Zeri with only a 42.9% win rate. Zeri has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Zeri's lead.

How do I play Seraphine against Zeri?

When playing Seraphine against Zeri, play cautiously and avoid Zeri's power spikes. Look for jungle assistance and team-dependent plays since Zeri has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.