Shame•Curse

Is Shame good in Slay the Spire 2?

Shame is a curse Curse curse in Slay the Spire 2. In combat it resolves as: At the end of your turn, if this is in your Hand, gain Frail. It ranks among the strongest cards its class can draft right now, earning a spot at S tier in our Slay the Spire 2 card tier list.

Across 13 recorded runs, decks running it win 45.5% of the time, comfortably clear of the 19.0% average, by 26.5%. It’s a more selective pick, turning up in just 0.3% of decks that could run it. Necrobinder players keep it in 0.2% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.4 times in the decks that take it.

It performs best next to Deflect — together they post a +4.9% swing in win rate. It also has strong chemistry with the relic Venerable Tea Set, which moves its win rate by +12.6%. At - energy, it’s upgraded in 0.0% of runs and usually joins the deck around floor 20.

That’s 5 wins, 6 deaths, and 2 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Test Subject Boss, which closes out 15.4% of its appearances. Read on for Shame’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Curse run.

Best Cards to Pair with Shame

Ranked by win-rate lift, Shame performs best alongside Deflect (+4.9%), Setup Strike (+4.9%), and Offering (+4.9%).

Deflect+4.9%4 runsSetup Strike+4.9%3 runsOffering+4.9%3 runsShrug It Off+4.9%3 runsStrike+0.8%3 runsDefend+0.8%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Shame Win Rate by Class

Shame is played across 5 classes, led by Necrobinder (100.0%), Silent (50.0%), and Regent (50.0%) by win rate.

The Necrobinder100.0%2 runsThe Silent50.0%3 runsThe Regent50.0%2 runsThe Ironclad33.3%4 runsThe Defect0.0%2 runs

Best Relics for Shame

Shame pairs best with the relics Venerable Tea Set (+12.6%), Meal Ticket (+12.6%), and Eternal Feather (+12.6%), ranked by win-rate lift.

Venerable Tea Set+12.6%3 runsMeal Ticket+12.6%3 runsEternal Feather+12.6%3 runsGremlin Horn+12.6%3 runsRegal Pillow+11.5%5 runsLantern+11.5%5 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Shame Card Details

Shame is a curse curse costing - energy; it’s upgraded in 0.0% of runs and usually picked up by floor 20.

At the end of your turn, if this is in your Hand, gain Frail.

What Ends Runs with Shame

Shame’s most common run-enders are Test Subject Boss (15.4%).

• Test Subject Boss15.4% of runs

See Also

Compare Shame with the rest of the best Slay the Spire 2 cards, relics, and classes below.