Nutritious Oyster•Relic

Is Nutritious Oyster good in Slay the Spire 2?

In Slay the Spire 2, Nutritious Oyster is an ancient relic you can pick up on your climb. Its effect: Upon pickup, raise your Max HP by. The data marks it as a weaker relic, settling at F tier — rarely a run-defining grab.

Over 82 tracked runs the win rate of decks holding it sits at 15.4%, 3.6% short of the 18.9% all-run baseline. It sees lighter play, carried in only 2.2% of runs. It does its best work in the hands of the Defect, who post a 18.2% win rate with it. Within Defect runs specifically, it’s carried 2.6% of the time.

Its standout card pairing is Thunder, which lifts the relic’s win rate by +84.6% when both are in play. It also works nicely with Rupture, good for a +84.6% win-rate change. It typically enters the deck near floor 1. As an ancient relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 10 ended in victory while 55 fell to a defeat. Its most common run-ender is Lagavulin Matriarch Boss, finishing 6.1% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Nutritious Oyster is worth grabbing.

Best Cards with Nutritious Oyster

The cards that gain the most from carrying Nutritious Oyster are Thunder (+84.6%), Rupture (+84.6%), and Royal Gamble (+51.3%), each shown with its win-rate swing.

Thunder+84.6%3 runsRupture+84.6%3 runsRoyal Gamble+51.3%3 runsManifest Authority+51.3%3 runsAfterimage+51.3%4 runsTesla Coil+51.3%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Nutritious Oyster Win Rate by Class

Of the 5 classes that carry Nutritious Oyster, it performs best with Defect (18.2%), Regent (18.2%), and Ironclad (16.7%).

The Defect18.2%15 runsThe Regent18.2%13 runsThe Ironclad16.7%19 runsThe Silent13.3%21 runsThe Necrobinder10.0%14 runs

Nutritious Oyster Details

Carried in 2.2% of runs, Nutritious Oyster is an ancient relic typically acquired near floor 1.

Upon pickup, raise your Max HP by.

What Ends Runs with Nutritious Oyster

Runs carrying Nutritious Oyster end most often against Lagavulin Matriarch Boss (6.1%), Entomancer Elite (6.1%), and Knowledge Demon Boss (4.9%) — the share of its runs each accounts for is shown.

• Lagavulin Matriarch Boss6.1% of runs
• Entomancer Elite6.1% of runs
• Knowledge Demon Boss4.9% of runs
• Decimillipede Elite4.9% of runs
• The Kin Boss3.7% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.