Toxic Egg
Win Rate
36.7%
Pick Rate
2.2%
Δ vs Avg
+22.8

Toxic Egg Relic

Rare
Rarity
Rare
Methodology
Data Methodology

Whenever you add a Skill into your Deck, Upgrade it.

Is Toxic Egg good in Slay the Spire 2?

In Slay the Spire 2, Toxic Egg is a rare relic you can pick up on your climb. Its effect: Whenever you add a Skill into your Deck, Upgrade it. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 455 tracked runs the win rate of decks holding it sits at 36.7%, 22.8% ahead of the 13.8% all-run baseline. It sees lighter play, carried in only 2.2% of runs. It does its best work in the hands of the Regent, who post a 45.6% win rate with it. Within Regent runs specifically, it’s carried 2.4% of the time.

Its standout card pairing is Sword Sage, which lifts the relic’s win rate by +46.7% when both are in play. It also works nicely with Fan of Knives, good for a +45.7% win-rate change. It typically enters the deck near floor 17. As a rare relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 165 ended in victory while 285 fell to a defeat. Its most common run-ender is Queen Boss, finishing 5.1% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Toxic Egg is worth grabbing.

Toxic Egg Win Rate & Pick Rate

At a 36.7% win rate, Toxic Egg runs 22.8% ahead of the 13.8% all-run baseline — the bars below put the two side by side.

Win rate36.7%
Average run13.8%
+22.8% vs averagePick rate: 2.2%455 runs

Run Outcomes with Toxic Egg

Across the 455 runs that carried Toxic Egg, 165 ended in a win and 290 in a loss — a 36.3% win share, counting abandons as losses.

  • Wins 36.3%
  • Losses 63.7%

Pick or Skip: Toxic Egg

Players take Toxic Egg in 60.1% of the 749 offers it appears in; those runs win 36.3% against 26.6% for runs that passed, a pick lift of +9.5% over 444 decided runs.

Pick rate when offered60.1%749 offers

Taken 450 times out of 749 offers.

Win rate when picked36.3%444 runs
Win rate when skipped26.6%286 runs
+9.7% vs skippingPick lift: +9.5%Sample OK

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Toxic Egg

The cards that gain the most from carrying Toxic Egg are Sword Sage (+46.7%), Fan of Knives (+45.7%), and Finisher (+35.5%), each shown with its win-rate swing.

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Toxic Egg Win Rate by Class

Of the 5 classes that carry Toxic Egg, it performs best with Regent (45.6%), Silent (40.0%), and Necrobinder (37.6%).

Toxic Egg Details

Carried in 2.2% of runs, Toxic Egg is a rare relic typically acquired near floor 17.

Whenever you add a Skill into your Deck, Upgrade it.

RarityRare
Typical pickup floor17
Pick rate2.2%
Runs tracked455

What Ends Runs with Toxic Egg

Runs carrying Toxic Egg end most often against Queen Boss (5.1%), Test Subject Boss (4.8%), and Kaiser Crab Boss (4.0%) — the share of its runs each accounts for is shown.

  • Queen Boss5.1% of runs
  • Test Subject Boss4.8% of runs
  • Kaiser Crab Boss4.0% of runs
  • Knowledge Demon Boss4.0% of runs
  • Decimillipede Elite3.5% of runs
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Toxic Egg – Frequently Asked Questions

Is Toxic Egg good in Slay the Spire 2?

Across 455 tracked runs carrying it, Toxic Egg wins 36.7% of the time — +22.8% above the average run. Win rate reflects how often runs with the relic end in victory.

What does Toxic Egg do in Slay the Spire 2?

Whenever you add a Skill into your Deck, Upgrade it.

How rare is Toxic Egg in Slay the Spire 2?

Toxic Egg is a Rare relic, picked up in 2.2% of tracked runs.

What is the best card to use with Toxic Egg?

In tracked runs, Toxic Egg has performed best alongside Sword Sage, which lifts its win rate by +46.7% over 18 runs together.

Which class is Toxic Egg best in?

Toxic Egg has its highest win rate with The Regent (45.6%).

Should I take Toxic Egg when it is offered?

Players take Toxic Egg in 60.1% of its 749 recorded offers. Runs that picked it win 36.3% (444 decided runs) against 26.6% for runs that skipped it (286 decided runs) — a +9.7% difference, and a +9.5% pick lift once sample size is accounted for.

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.