Annie, League of Legends champion
Win Rate
49.6%
Pick Rate
1.0%
Ban Rate
0.9%

Annie Mid Runes: Keystone & Shards

Annie F TierMageSupport
Patch
26.20
Games
1,334
Lane
Mid
Tier
All Tiers
Last Updated
Oct 14, 2026 UTC
Methodology
Data Methodology

Best Mid Annie runes for LoL Patch 26.20 - Electrocute from the Domination tree with Sorcery secondary (50.7% WR, 39.1% pick rate). Annie's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Secondary tree: Absolute Focus, Axiom Arcanist.

Annie performs best with Electrocute as the keystone rune from the Domination tree. Annie's optimal primary runes are Electrocute, Cheap Shot, Grisly Mementos, Relentless Hunter. Annie's secondary rune tree is Sorcery with Absolute Focus, Axiom Arcanist. This rune setup achieves a 50.67% win rate (+1.0% win rate difference) with a 39.1% pick rate across 521 Annie games.
50.7%Win Rate
+1.0%WR Diff
39.1%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Absolute FocusAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

Axiom ArcanistAxiom Arcanist

Your Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)

Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.

This alternative Annie rune build uses Deathfire Touch as the keystone from the Sorcery tree. The primary runes are Deathfire Touch, Manaflow Band, Celerity, Scorch. Annie's secondary rune tree is Precision with Cut Down, Legend: Haste. This setup achieves a 52.38% win rate (+2.8% win rate difference) with a 9.4% pick rate across 126 games.
52.4%Win Rate
+2.8%WR Diff
9.4%Pick Rate
Deathfire TouchDeathfire Touch

Damaging a champion with an ability burns them for 3 - 12 based on level (+2.5% AP) (+7% bonus AD) magic damage per second. After burning for 3 seconds, the damage of the burn increases by 75% while they remain on fire.

Duration:
Single Target: 4s
Area of Effect: 2s
Damage over Time: 1s

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

CelerityCelerity

All movement bonuses are 7% more effective on you and gain 1% Move Speed.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Cut DownCut Down

Deal 8% more damage to champions who have more than 60% health.

Legend: HasteLegend: Haste

Gain 1.5 basic ability haste for every Legend stack (max 10 stacks).

Earn progress toward Legend stacks for every champion takedown, epic monster takedown, large monster kill, and minion kill.

These champions share at least 4 runes with Annie's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Annie's playstyle or want to learn champions with familiar rune setups.Orianna, Aurelion Sol, Vel'Koz, Anivia, Taliyah

Every Annie Mid Keystone and Secondary Tree (Patch 26.20)

1,295 games

Annie Mid runs Electrocute in 75% of games, with a 50.1% win rate. Sorcery is the usual secondary tree (67%). Standard stat shards: Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense).

Keystones

RunePlayersWin RateGames
ElectrocuteElectrocuteMost played75.0%50.1%971
Deathfire TouchDeathfire Touch16.8%50.0%218
First StrikeFirst Strike3.6%39.1%46

Secondary trees

RunePlayersWin RateGames
SorcerySorceryMost played67.0%50.1%868
PrecisionPrecision14.1%49.7%183
InspirationInspiration10.5%50.0%136
DominationDomination5.2%38.8%67
ResolveResolve3.2%48.8%41

Pick rate is the share of Annie games in this lane that used the rune; options under 40 games are left out. A higher win rate on a rarely picked rune is usually a matchup-specific choice, not a general upgrade.

Annie Minor Runes by Tree

Every minor rune Annie players take, grouped by rune tree, with how often it is picked and how often it wins.

Domination

RunePlayersWin RateGames
Cheap ShotCheap ShotMost played74.7%49.5%967
Grisly MementosGrisly Mementos71.4%49.4%924
Relentless HunterRelentless Hunter57.0%48.5%738
Ultimate HunterUltimate Hunter21.7%52.3%281
Taste of BloodTaste of Blood5.7%43.2%74
Sixth SenseSixth Sense4.6%58.3%60

Sorcery

RunePlayersWin RateGames
Axiom ArcanistAxiom ArcanistMost played61.5%49.0%796
Absolute FocusAbsolute Focus58.8%50.3%762
ScorchScorch21.3%51.4%276
Manaflow BandManaflow Band20.8%52.2%270
CelerityCelerity15.3%50.5%198
TranscendenceTranscendence8.3%46.3%108

Precision

RunePlayersWin RateGames
Legend: HasteLegend: HasteMost played13.1%50.6%170
Cut DownCut Down13.0%49.4%168

Inspiration

RunePlayersWin RateGames
Cosmic InsightCosmic InsightMost played12.8%46.4%166
Biscuit DeliveryBiscuit Delivery10.2%48.5%132
Triple TonicTriple Tonic3.1%47.5%40

Annie Stat Shards

Which stat shards Annie players choose in each of the three shard rows, and the win rate of each.

RunePlayersWin RateGames
Adaptive Force (flex)Adaptive Force (flex)Most played82.8%49.2%1,072
Health Scaling (defense)Health Scaling (defense)74.8%48.5%969
Adaptive Force (offense)Adaptive Force (offense)70.3%49.7%910
Attack Speed (offense)Attack Speed (offense)24.7%50.0%320
Health (defense)Health (defense)23.4%51.8%303
Move Speed (flex)Move Speed (flex)16.5%50.0%214
Ability Haste (offense)Ability Haste (offense)5.0%43.1%65
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Annie Runes FAQ - Patch 26.20

What is the best keystone for Annie Mid?

Electrocute: Annie Mid takes it in 75% of ranked games and wins 50.1% of 971 games. Alternatives: Deathfire Touch (17%, 50.0%), First Strike (4%, 39.1%).

What stat shards should Annie take?

Most Annie players take Adaptive Force (offense), Adaptive Force (flex), Health Scaling (defense) — one from each shard row.

What are the best Annie runes in patch 26.20?

The best Annie runes in patch 26.20 use the Domination tree with Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, and the Sorcery tree with Absolute Focus and Axiom Arcanist. This rune setup achieves a 50.7% win rate with a 39.1% pick rate.

What is the win rate for Annie's best rune page?

Annie's best rune page has a 50.7% win rate in patch 26.20, which is +1.0% compared to Annie's average win rate. This rune setup has a 39.1% pick rate among Annie players.

What keystone should I use on Annie?

Electrocute from the Domination tree is the best keystone rune for Annie in patch 26.20. This keystone synergizes well with Annie's kit and provides a 50.7% win rate.

What is Annie's primary rune tree?

Annie's primary rune tree is Domination. The optimal Domination runes for Annie are Electrocute, Cheap Shot, Grisly Mementos, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Annie's secondary rune tree?

Annie's best secondary rune tree is Sorcery. The recommended Sorcery runes are Absolute Focus and Axiom Arcanist, which complement Annie's Domination primary tree.

What are alternative rune setups for Annie?

An alternative Annie rune setup uses Deathfire Touch from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Annie's runes?

Annie's top rune page has a 39.1% pick rate in patch 26.20. This indicates that 39.1% of Annie players use the Electrocute setup with Domination and Sorcery trees.