
Elise Runes
The top Elise runes in LoL patch 25.23 are Dark Harvest, Cheap Shot, Sixth Sense, Relentless Hunter for Elise's primary runes. Elise's runes in his secondary tree best utilizes Triumph and Cut Down. These Elise rune choices provide the best Elise rune build for ranked.


Spider Queen
Human Form: When Elise's abilities hit an enemy, she gains a dormant Spiderling.
Spider Form: Basic attacks deal bonus magic damage and restore health to Elise.

Neurotoxin / Venomous Bite
Human Form: Deals damage based upon how high the target's Health is.
Spider Form: Lunges at an enemy and deals damage based upon how low their Health is.Cost:- 80/
- 85/
- 90/
- 95/
- 100
Cooldown:- 6
Range:- 615


Volatile Spiderling / Skittering Frenzy
Human Form: Releases a venom-gorged Spiderling that explodes when it nears a target.
Spider Form: Elise and her Spiderlings gain Attack Speed.Cost:- 60/
- 70/
- 80/
- 90/
- 100
Cooldown:- 12
Range:- 950


Cocoon / Rappel
Human Form: Stuns the first enemy unit hit and reveals them if they are not stealthed.
Spider Form: Elise and her Spiderlings ascend into the air and then descend upon target enemy. After descending on an enemy target, Elise's bonus damage and healing from Spider Queen is increased.Cost:- 50
Cooldown:- 12/
- 12/
- 11/
- 11/
- 10
Range:- 1075


Spider Form
Transforms into a menacing spider, reducing her attack range in exchange for Move Speed, new abilities, and a Spiderling swarm that will attack her foes.
Cost:- 0
Cooldown:- 3
Range:- 20
- Assassin,
- Mage

Elise performs best with Dark Harvest as the keystone rune. The optimal primary runes for Elise include Dark Harvest, Cheap Shot, Sixth Sense. This rune setup achieves a 1.00% win rate across 1 Elise games.
Primary Tree
DominationThis alternative Elise rune build uses Dark Harvest as the keystone. This setup provides a different playstyle for Elise and achieves a 1.00% win rate. Consider this rune page when facing specific matchups or team compositions.
Primary Tree
DominationElise Runes - Frequently Asked Questions
What are the best Elise runes?
The best Elise runes in patch 25.23 are Dark Harvest, Cheap Shot, Sixth Sense, and Relentless Hunter for the primary tree, and Triumph and Cut Down for the secondary tree. These runes provide optimal performance for Elise.
What keystone should I use on Elise?
Dark Harvest is the best keystone rune for Elise. This keystone synergizes well with Elise's abilities and provides maximum value in most matchups.
What are Elise's secondary runes?
Elise's best secondary runes are Triumph and Cut Down. These secondary runes complement Elise's primary rune choices and enhance overall effectiveness.
Can I use different rune setups on Elise?
Yes, Elise can utilize different rune setups depending on matchup and playstyle. While Dark Harvest is most popular, alternative keystones may work better in specific situations.


























