Seraphine - League of Legends Champion
Win Rate
52.4%
Pick Rate
10.0%

Seraphinevs Neeko

SSupportMage
Patch26.14
Matches226,800
LaneAll Lanes
TierAll Tiers
Last UpdatedJul 21, 2026
MethodologyData Methodology

Seraphine vs Neeko is a moderate matchup in LoL patch 26.14. Seraphine wins with a 51.5% win rate (+3.0%) over Neeko based on 33 games. Neeko wins the early laning phase while Seraphine scales better into the late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Neeko matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 51.5% win rate in this matchup
Seraphine
51.5% WR
VS
Neeko vs Seraphine matchup - 48.5% win rate
Neeko
48.5% WR

Who Wins the Seraphine vs Neeko Matchup?

Seraphine wins the Seraphine vs Neeko matchup
Winner
Seraphine
Matches: 33
51.5%
Win Rate
48.5%
1.5
CS / min
1.9
504
DMG / min
565
8,360
Gold / game
8,453
229
Heal / min
101
327
DMG Mitigated / min
355
1.1
CC / min
1.4
43.8%
Early Game WR
56.3%
58.8%
Late Game WR
41.2%

Seraphine vs Neeko Matchup Summary

The Seraphine vs Neeko matchup is a moderate matchup in League of Legends ranked play. Based on 33 recent matches analyzed, Seraphine wins with a 51.5% win rate compared to Neeko's 48.5%, giving Seraphine a 3.0 percentage point advantage. Game phase dynamics play a critical role here: Neeko controls the early laning stage, but Seraphine outscales as the game goes longer. The matchup shifts dramatically depending on game length — Neeko needs to press advantages before Seraphine reaches their power spikes, while Seraphine should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in CS, where Neeko leads by 0.4 CS/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine has a statistical edge, but the margin is close enough that respecting Neeko's strengths is important. Trade when cooldowns are favorable, track the enemy jungler, and build toward your strongest item spikes to convert the slight advantage into a decisive lead. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Neeko Laning Phase Breakdown

Neeko wins the laning phase against Seraphine in League of Legends

Neeko is favored during the laning phase against Seraphine, winning 4 out of 5 key stat categories. Neeko holds advantages in farming, damage, gold income and crowd control, making them the stronger laner in this matchup.

Farming
1.5Seraphine
1.9Neeko
Neeko edges out Seraphine by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Neeko.
Damage
504Seraphine
565Neeko
Neeko deals 61 more champion damage per minute than Seraphine. While noticeable in extended trades, this gap can be offset by Seraphine choosing favorable fight windows, such as engaging when Neeko's key abilities are on cooldown or trading immediately after dodging a skillshot.
Economy
8,360Seraphine
8,453Neeko
Seraphine and Neeko generate nearly equal gold per game, with just a 93 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.1Seraphine
1.4Neeko
Both Seraphine and Neeko provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
556Seraphine
457Neeko
Seraphine heals and mitigates 100 more damage per minute than Neeko, providing moderate extra durability. This sustain edge allows Seraphine to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Neeko.

Best Seraphine Build Against Neeko

Ionian Boots of Lucidity is the optimal boots choice against Neeko, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Neeko are Luden's Echo, Echoes of Helia and Imperial Mandate. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 2 games — well above average and making it the top item path against Neeko. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Neeko matchup.

Early Game vs Late Game

Early Game
Neeko
56.3%
+12.5% advantage
Seraphine early game win rateSeraphine43.8%
Neeko early game win rateNeeko56.3%
Late Game
Seraphine
58.8%
+17.6% advantage
Seraphine late game win rateSeraphine58.8%
Neeko late game win rateNeeko41.2%

Neeko dominates the early game (first 15 minutes) with a commanding 56.3% win rate — a 12.5 percentage point lead over Seraphine. This lopsided early game means Neeko can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 58.8% win rate — 17.6 points above Neeko. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Neeko must aggressively press their early advantage and close out the game before Seraphine reaches their scaling breakpoints. If Seraphine survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Seraphine Runes Against Neeko

Sorcery rune tree - Seraphine primary runes vs NeekoSorcery
Summon Aery - best Seraphine rune vs NeekoManaflow Band - best Seraphine rune vs NeekoTranscendence - best Seraphine rune vs NeekoGathering Storm - best Seraphine rune vs Neeko
Resolve rune tree - Seraphine secondary runes vs NeekoResolve
Font of Life - best Seraphine rune vs NeekoRevitalize - best Seraphine rune vs Neeko
42.9% WR

Running Sorcery primary with Resolve secondary allows Seraphine to press their advantage against Neeko, amplifying the strengths that make this a favorable matchup.


Seraphine matchup data for League of Legends patch 26.14. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.14
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
55.85%2991.74719,29548.1%60.0%
49.76%2071.55128,84357.0%45.3%
47.70%1741.55109,00848.0%47.4%
49.13%1731.44618,48850.0%48.5%
49.12%1711.64808,75953.7%46.1%
47.06%1531.55109,22549.1%45.8%
48.30%1471.95329,70651.0%46.9%
50.38%1331.54679,03049.0%51.2%
45.97%1241.44288,53360.0%36.5%
48.21%1121.44729,01753.3%44.8%
54.55%1102.35059,68744.4%59.5%
46.79%1091.55018,61150.0%44.4%
57.41%1081.45369,50765.8%52.2%
55.32%941.85399,07347.4%60.7%
50.56%891.44849,28360.0%45.8%
52.87%871.34668,26252.8%52.9%
57.65%851.54169,35765.6%52.8%
57.50%805.372411,20659.3%56.6%
45.45%771.64769,99525.0%50.8%
63.16%761.55059,33854.8%68.9%
57.89%761.75148,58067.6%48.7%
50.00%721.64569,53364.0%42.5%
50.00%662.04959,25747.8%51.2%
50.77%651.46317,61950.0%51.6%
53.85%656.077710,54060.0%48.6%
46.88%641.34479,18159.1%40.5%
52.46%611.54608,55950.0%54.0%
51.72%581.45178,94657.7%46.9%
53.45%581.35148,75145.5%58.3%
43.86%571.45249,59460.0%38.1%
54.55%551.55419,53777.8%43.2%
52.83%531.44887,86337.5%65.5%
52.94%513.765010,65950.0%54.3%
53.49%436.17089,63055.2%50.0%
56.10%411.44789,02957.1%55.0%
36.84%385.975311,16633.3%38.5%
51.52%331.55048,36043.8%58.8%
54.55%331.44978,85036.4%63.6%
62.50%325.476410,80441.7%75.0%
35.48%311.54698,95836.4%35.0%
54.84%311.94618,75463.6%50.0%
55.17%293.267211,13925.0%66.7%
60.71%284.15919,88872.7%52.9%
32.14%286.176410,58033.3%31.3%
69.23%265.776110,57085.7%50.0%
70.83%241.45079,19650.0%81.3%
56.52%236.182912,78350.0%60.0%
56.52%231.85069,03258.3%54.5%
47.62%213.564410,63366.7%40.0%
57.14%211.66148,42960.0%54.5%
42.86%211.648511,10033.3%44.4%
63.16%195.569112,81460.0%64.3%
63.16%191.75289,58566.7%60.0%
47.37%196.387810,25960.0%33.3%
50.00%186.580110,04650.0%50.0%
50.00%186.280711,85837.5%60.0%
50.00%186.885311,27550.0%50.0%
56.25%165.472113,6070.0%69.2%
50.00%164.861610,99950.0%50.0%
56.25%165.866011,976100.0%36.4%
75.00%162.24547,74077.8%71.4%
80.00%152.472410,151100.0%66.7%
66.67%152.474310,11660.0%70.0%
42.86%145.879310,92340.0%44.4%
61.54%131.44069,43660.0%62.5%
66.67%126.279211,77420.0%100.0%
33.33%125.16559,89640.0%28.6%
54.55%113.46429,30060.0%50.0%
40.00%101.35288,42020.0%60.0%
40.00%105.289411,60625.0%50.0%
80.00%102.254811,212100.0%71.4%
55.56%94.86278,88680.0%25.0%
44.44%96.47018,84342.9%50.0%
55.56%91.655510,08533.3%66.7%
25.00%85.075011,78850.0%16.7%
85.71%75.55249,75775.0%100.0%
57.14%71.55089,13366.7%50.0%
42.86%75.566910,94833.3%50.0%
85.71%76.187613,23166.7%100.0%
42.86%74.36429,62220.0%100.0%
57.14%73.050210,97250.0%60.0%
57.14%72.667710,02866.7%50.0%
71.43%73.04619,27766.7%75.0%
28.57%73.673212,7790.0%33.3%
66.67%65.886412,97750.0%75.0%
50.00%64.85639,34966.7%33.3%
33.33%66.786113,96850.0%25.0%
66.67%65.56098,223100.0%0.0%
83.33%64.062711,888100.0%80.0%
50.00%64.249210,633100.0%25.0%
100.00%64.68619,415100.0%100.0%
80.00%52.45339,18466.7%100.0%
60.00%51.55748,068100.0%33.3%
80.00%55.787512,964100.0%75.0%
40.00%51.64836,62350.0%33.3%
60.00%53.08026,67733.3%100.0%
100.00%52.36298,546100.0%100.0%
60.00%54.26028,77833.3%100.0%
60.00%54.74626,532100.0%33.3%
40.00%56.485013,194100.0%0.0%
20.00%53.473711,9840.0%33.3%
100.00%55.51,02313,201100.0%100.0%

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Seraphine vs Neeko - Frequently Asked Questions

How does Seraphine do against Neeko in League of Legends?

Seraphine wins the Seraphine vs Neeko matchup with a 51.5% win rate compared to Neeko's 48.5%, a 3.0 percentage point difference. This data is based on 33 recent ranked games in patch 26.14.

How does Seraphine do against Neeko in the early game?

In the early game, Neeko has the advantage against Seraphine with a 56.3% win rate versus 43.8%. Neeko players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Neeko in the late game?

In the late game, Seraphine takes over the Seraphine vs Neeko matchup with a 58.8% win rate compared to 41.2%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Neeko matchup?

Seraphine wins the matchup against Neeko with a 51.5% win rate in League of Legends patch 26.14. The 3.0 percentage point advantage means Seraphine is moderately favored in this lane matchup based on 33 games analyzed.

What is the best Seraphine build against Neeko?

The best Seraphine build against Neeko includes Luden's Echo, Echoes of Helia, Imperial Mandate with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Neeko?

The best Seraphine runes against Neeko use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 42.9% win rate in the Seraphine vs Neeko matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Neeko?

Yes, Seraphine has a favorable matchup against Neeko with a 51.5% win rate. Seraphine has a solid advantage over Neeko in lane based on current patch 26.14 data.

How do I play Seraphine against Neeko?

When playing Seraphine against Neeko, leverage your statistical advantages by trading aggressively during favorable windows. Play safe early and scale into your power spikes where you outperform Neeko. Build the recommended items and runes for this specific matchup for the best results.