Seraphine - League of Legends Champion
Win Rate
52.3%
Pick Rate
7.8%

Seraphinevs Neeko

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 5, 2026
MethodologyData Methodology

Seraphine vs Neeko is a decisive matchup in LoL patch 26.11. Seraphine wins with a 61.3% win rate (+22.6%) over Neeko based on 124 games. Seraphine holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Neeko matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 61.3% win rate in this matchup
Seraphine
61.3% WR
VS
Neeko vs Seraphine matchup - 38.7% win rate
Neeko
38.7% WR

Who Wins the Seraphine vs Neeko Matchup?

Seraphine wins the Seraphine vs Neeko matchup
Winner
Seraphine
Matches: 124
61.3%
Win Rate
38.7%
1.6
CS / min
1.9
481
DMG / min
582
9,075
Gold / game
8,988
300
Heal / min
85
367
DMG Mitigated / min
347
1.1
CC / min
1.4
67.7%
Early Game WR
32.3%
54.8%
Late Game WR
45.2%

Seraphine vs Neeko Matchup Summary

The Seraphine vs Neeko matchup is a decisive matchup in League of Legends ranked play. Based on 124 recent matches analyzed, Seraphine wins with a 61.3% win rate compared to Neeko's 38.7%, giving Seraphine a 22.6 percentage point advantage. Seraphine dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Neeko players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Seraphine leads by 235 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Seraphine players can confidently pick into Neeko and play aggressively from level 1. Look to establish lane dominance early through favorable trades and zone Neeko away from CS whenever possible. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Neeko Laning Phase Breakdown

Neeko wins the laning phase against Seraphine in League of Legends

Neeko is favored during the laning phase against Seraphine, winning 3 out of 5 key stat categories. Neeko holds advantages in farming, damage and crowd control, making them the stronger laner in this matchup.

Farming
1.6Seraphine
1.9Neeko
Seraphine and Neeko farm at nearly identical rates in this matchup, with only a 0.3 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
481Seraphine
582Neeko
Neeko heavily out-damages Seraphine by 102 DMG/min, dominating both short trades and all-in fights. Seraphine should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Neeko's sustained damage advantage take over.
Economy
9,075Seraphine
8,988Neeko
Seraphine and Neeko generate nearly equal gold per game, with just a 86 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.1Seraphine
1.4Neeko
Both Seraphine and Neeko provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
667Seraphine
432Neeko
Seraphine vastly out-sustains Neeko, healing and mitigating 235 more damage per minute. This massive durability gap means Seraphine can absorb significant punishment and remain in lane while Neeko is forced to recall. Building grievous wounds early is essential for Neeko, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Neeko

Ionian Boots of Lucidity is the optimal boots choice against Neeko, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Neeko are Echoes of Helia, Rylai's Crystal Scepter and Diadem of Songs. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 5 games — well above average and making it the top item path against Neeko. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Neeko matchup.

Early Game vs Late Game

Early Game
Seraphine
67.7%
+35.5% advantage
Seraphine early game win rateSeraphine67.7%
Neeko early game win rateNeeko32.3%
Late Game
Seraphine
54.8%
+9.7% advantage
Seraphine late game win rateSeraphine54.8%
Neeko late game win rateNeeko45.2%

Seraphine dominates the early game (first 15 minutes) with a commanding 67.7% win rate — a 35.5 percentage point lead over Neeko. This lopsided early game means Seraphine can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Seraphine is far superior in the late game (25+ minutes), boasting a 54.8% win rate — 9.7 points above Neeko. Extended games heavily favor Seraphine, whose kit and scaling make them a dominant force in team fights and objective control.

Seraphine holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Neeko players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Neeko

Sorcery rune tree - Seraphine primary runes vs NeekoSorcery
Arcane Comet - best Seraphine rune vs NeekoManaflow Band - best Seraphine rune vs NeekoTranscendence - best Seraphine rune vs NeekoScorch - best Seraphine rune vs Neeko
Inspiration rune tree - Seraphine secondary runes vs NeekoInspiration
Biscuit Delivery - best Seraphine rune vs NeekoCosmic Insight - best Seraphine rune vs Neeko
68.8% WR

Running Sorcery primary with Inspiration secondary allows Seraphine to press their advantage against Neeko, amplifying the strengths that make this a favorable matchup.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Neeko - Frequently Asked Questions

How does Seraphine do against Neeko in League of Legends?

Seraphine wins the Seraphine vs Neeko matchup with a 61.3% win rate compared to Neeko's 38.7%, a 22.6 percentage point difference. This data is based on 124 recent ranked games in patch 26.11.

How does Seraphine do against Neeko in the early game?

In the early game, Seraphine has the advantage against Neeko with a 67.7% win rate versus 32.3%. Seraphine players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Neeko in the late game?

In the late game, Seraphine takes over the Seraphine vs Neeko matchup with a 54.8% win rate compared to 45.2%. Seraphine scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Neeko matchup?

Seraphine wins the matchup against Neeko with a 61.3% win rate in League of Legends patch 26.11. The 22.6 percentage point advantage means Seraphine is significantly favored in this lane matchup based on 124 games analyzed.

What is the best Seraphine build against Neeko?

The best Seraphine build against Neeko includes Echoes of Helia, Rylai's Crystal Scepter, Diadem of Songs with Ionian Boots of Lucidity. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Neeko?

The best Seraphine runes against Neeko use the Sorcery primary tree with Inspiration secondary. This rune setup achieves a 68.8% win rate in the Seraphine vs Neeko matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Neeko?

Yes, Seraphine has a favorable matchup against Neeko with a 61.3% win rate. Seraphine strongly counters Neeko in lane based on current patch 26.11 data.

How do I play Seraphine against Neeko?

When playing Seraphine against Neeko, leverage your statistical advantages by trading aggressively during favorable windows. You have early game priority — look for kills and zone control before first recall. Build the recommended items and runes for this specific matchup for the best results.