Leafy Poultice Relic

Is Leafy Poultice good in Slay the Spire 2?

In Slay the Spire 2, Leafy Poultice is an ancient relic you can pick up on your climb. Its effect: Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose Max HP. The data marks it as a weaker relic, settling at F tier — rarely a run-defining grab.

Over 1081 tracked runs the win rate of decks holding it sits at 16.4%, 2.6% ahead of the 13.8% all-run baseline. It sees lighter play, carried in only 5.2% of runs. It does its best work in the hands of the Necrobinder, who post a 25.0% win rate with it. Within Necrobinder runs specifically, it’s carried 5.7% of the time.

Its standout card pairing is Mad Science, which lifts the relic’s win rate by +56.9% when both are in play. It also works nicely with Neurosurge, good for a +56.6% win-rate change. It typically enters the deck near floor 1. As an ancient relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 176 ended in victory while 894 fell to a defeat. Its most common run-ender is Decimillipede Elite, finishing 3.4% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Leafy Poultice is worth grabbing.

Pick or Skip: Leafy Poultice

Across 1081 offers Leafy Poultice has a 100.0% pick rate; the 1081 runs that took it and 0 that left it are still below the sample floor, so no win rate is shown.

Taken 1081 times out of 1081 offers.

A win rate is only shown once that side clears the sample floor. Below it you get the run counts and nothing else — a 0% here would be a reporting artefact, not a result.

Pick rate when offered counts offers, not runs: out of every time the game put this in front of a player, how often it was taken. It is not the same number as the share of runs that end up containing it.

Pick lift is the sample-adjusted gap between runs that took the option and runs that passed on it. It is the fair way to rank choices, because raw win rates put the smallest samples on top.

Best Cards with Leafy Poultice

The cards that gain the most from carrying Leafy Poultice are Mad Science (+56.9%), Neurosurge (+56.6%), and Hang (+44.7%), each shown with its win-rate swing.

Mad Science+56.9%45 runsNeurosurge+56.6%26 runsHang+44.7%18 runsTransfigure+43.5%21 runsCapture Spirit+43.5%30 runsBlade of Ink+42.6%22 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Leafy Poultice Win Rate by Class

Of the 5 classes that carry Leafy Poultice, it performs best with Necrobinder (25.0%), Silent (20.8%), and Regent (16.9%).

The Necrobinder25.0%206 runsThe Silent20.8%237 runsThe Regent16.9%178 runsThe Defect10.9%186 runsThe Ironclad9.5%268 runs

Leafy Poultice Details

Carried in 5.2% of runs, Leafy Poultice is an ancient relic typically acquired near floor 1.

Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose Max HP.

What Ends Runs with Leafy Poultice

Runs carrying Leafy Poultice end most often against Decimillipede Elite (3.4%), Knowledge Demon Boss (2.9%), and Waterfall Giant Boss (2.9%) — the share of its runs each accounts for is shown.

• Decimillipede Elite3.4% of runs
• Knowledge Demon Boss2.9% of runs
• Waterfall Giant Boss2.9% of runs
• The Insatiable Boss2.6% of runs
• Infested Prisms Elite2.6% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.