Leafy Poultice•Relic

Is Leafy Poultice good in Slay the Spire 2?

In Slay the Spire 2, Leafy Poultice is an ancient relic you can pick up on your climb. Its effect: Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose Max HP. The data marks it as a weaker relic, settling at D tier — rarely a run-defining grab.

Over 43 tracked runs the win rate of decks holding it sits at 25.7%, 13.1% ahead of the 12.6% all-run baseline. It sees lighter play, carried in only 8.3% of runs. It does its best work in the hands of the Ironclad, who post a 75.0% win rate with it. Within Ironclad runs specifically, it’s carried 8.2% of the time.

Its standout card pairing is Survivor, which lifts the relic’s win rate by +74.3% when both are in play. It also works nicely with Prepared, good for a +74.3% win-rate change. It typically enters the deck near floor 1. As an ancient relic, how often it’s offered depends on its rarity tier.

Of the runs that carried it, 9 ended in victory while 26 fell to a defeat. Its most common run-ender is Vantom Boss, finishing 9.3% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Leafy Poultice is worth grabbing.

Best Cards with Leafy Poultice

The cards that gain the most from carrying Leafy Poultice are Survivor (+74.3%), Prepared (+74.3%), and Mayhem (+74.3%), each shown with its win-rate swing.

Survivor+74.3%5 runsPrepared+74.3%3 runsMayhem+74.3%4 runsFan of Knives+74.3%3 runsDefend+49.3%4 runsBash+49.3%4 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Leafy Poultice Win Rate by Class

Of the 5 classes that carry Leafy Poultice, it performs best with Ironclad (75.0%), Silent (50.0%), and Necrobinder (20.0%).

The Ironclad75.0%4 runsThe Silent50.0%6 runsThe Necrobinder20.0%18 runsThe Regent20.0%11 runsThe Defect0.0%4 runs

Leafy Poultice Details

Carried in 8.3% of runs, Leafy Poultice is an ancient relic typically acquired near floor 1.

Upon pickup, Transform 1 of your Strikes and 1 of your Defends and lose Max HP.

What Ends Runs with Leafy Poultice

Runs carrying Leafy Poultice end most often against Vantom Boss (9.3%), Infested Prisms Elite (7.0%), and Skulking Colony Elite (4.7%) — the share of its runs each accounts for is shown.

• Vantom Boss9.3% of runs
• Infested Prisms Elite7.0% of runs
• Skulking Colony Elite4.7% of runs

See Also

Keep exploring Slay the Spire 2 tier lists and stats below.