
Neow's TalismanRelic
Upon pickup, Upgrade 1 of your Strikes and 1 of your Defends.
Is Neow's Talisman good in Slay the Spire 2?
Neow's Talisman is an ancient relic in Slay the Spire 2. While carried, it does the following: Upon pickup, Upgrade 1 of your Strikes and 1 of your Defends. It currently underperforms most relics, sitting at F tier in our Slay the Spire 2 relic rankings.
Across 38 recorded runs, decks carrying it win 17.2% of the time, trailing the 18.9% average by 1.7%. It’s a more situational relic, showing up in just 1.0% of runs. The class that gets the most out of it is the Regent, at a 66.7% win rate. Regent players hold onto it in 0.7% of their runs.
It combos especially well with Dagger Throw, worth a +82.8% win-rate swing together. Another strong card to run with it is Falling Star, worth +49.4% to its win rate. On average it’s acquired around floor 1 of a run. Its ancient rarity shapes how frequently you’ll run into it.
It has 5 run wins against 24 losses in our tracked data. When runs carrying it end, the most frequent culprit is Kaiser Crab Boss, which closes out 5.3% of them. Read on for Neow's Talisman’s complete card, class, and threat breakdown before you decide to pick it up.
Neow's Talisman Win Rate & Pick Rate
Neow's Talisman’s 17.2% win rate trails the 18.9% all-run average by 1.7%, the gap charted below.
Run Outcomes with Neow's Talisman
Neow's Talisman has 5 wins and 33 losses over 38 tracked runs (13.2% won); abandoned runs count as losses.
- Wins 13.2%
- Losses 86.8%
Best Cards with Neow's Talisman
Ranked by win-rate lift, the best cards to run with Neow's Talisman are Dagger Throw (+82.8%), Falling Star (+49.4%), and Venerate (+49.4%).
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Neow's Talisman Details
Neow's Talisman is an ancient relic carried in 1.0% of runs and usually picked up around floor 1.
Upon pickup, Upgrade 1 of your Strikes and 1 of your Defends.
What Ends Runs with Neow's Talisman
Neow's Talisman’s most common run-enders are Kaiser Crab Boss (5.3%), Queen Boss (5.3%), and The Insatiable Boss (5.3%).
- Kaiser Crab Boss5.3% of runs
- Queen Boss5.3% of runs
- The Insatiable Boss5.3% of runs
- Lagavulin Matriarch Boss5.3% of runs
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Neow's Talisman – Frequently Asked Questions
Is Neow's Talisman good in Slay the Spire 2?
Across 38 tracked runs carrying it, Neow's Talisman wins 17.2% of the time — +1.7% below the average run. Win rate reflects how often runs with the relic end in victory.
What does Neow's Talisman do in Slay the Spire 2?
Upon pickup, Upgrade 1 of your Strikes and 1 of your Defends.
How rare is Neow's Talisman in Slay the Spire 2?
Neow's Talisman is an Ancient relic, picked up in 1.0% of tracked runs.
What is the best card to use with Neow's Talisman?
In tracked runs, Neow's Talisman has performed best alongside Dagger Throw, which lifts its win rate by +82.8% over 3 runs together.
Which class is Neow's Talisman best in?
Neow's Talisman has its highest win rate with The Regent (66.7%).
See Also
Compare Neow's Talisman with the rest of the best Slay the Spire 2 relics, cards, and classes below.