Annie - League of Legends Champion
Win Rate
50.1%
Pick Rate
1.5%

AnnieRunes

CMageSupport
Patch26.5
Matches469,660
LaneAll Lanes
TierAll Tiers
Last UpdatedMar 12, 2026
MethodologyData Methodology

Best Annie runes for LoL Patch 26.5 - Electrocute from the Domination tree with Sorcery secondary (68.8% WR, 1.2% pick rate). Annie's optimal primary runes are Electrocute, Cheap Shot, Sixth Sense, Relentless Hunter. Secondary tree: Absolute Focus, Axiom Arcanist.

Annie performs best with Electrocute as the keystone rune from the Domination tree. Annie's optimal primary runes are Electrocute, Cheap Shot, Sixth Sense, Relentless Hunter. Annie's secondary rune tree is Sorcery with Absolute Focus, Axiom Arcanist. This rune setup achieves a 68.75% win rate (+18.6% win rate difference) with a 1.2% pick rate across 16 Annie games.
68.8%Win Rate
+18.6%WR Diff
1.2%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Cheap ShotCheap Shot

Damaging champions with impaired movement or actions deals 10 - 45 bonus true damage (based on level).

Cooldown: 4s
Activates on damage occurring after the impairment.

Sixth SenseSixth Sense

Automatically sense a nearby untracked and unseen ward, tracking it for the team.

Level 11: Also reveal the ward for 10s.

This effect has a 250 second Cooldown.

Relentless HunterRelentless Hunter

Gain 8 Move Speed out of combat per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

Absolute FocusAbsolute Focus

While above 70% health, gain an adaptive bonus of up to 18 Attack Damage or 30 Ability Power (based on level).

Grants 1.8 Attack Damage or 3 Ability Power at level 1.

Axiom ArcanistAxiom Arcanist

Your Ultimate has 12% increased damage, healing, and shielding.
(AoE damage is reduced to a 8% increase)

Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown by 7%.

This alternative Annie rune build uses Summon Aery as the keystone from the Sorcery tree. The primary runes are Summon Aery, Manaflow Band, Transcendence, Scorch. Annie's secondary rune tree is Inspiration with Biscuit Delivery, Cosmic Insight. This setup achieves a 52.94% win rate (+2.8% win rate difference) with a 2.6% pick rate across 34 games.
52.9%Win Rate
+2.8%WR Diff
2.6%Pick Rate
Summon AerySummon Aery

Damaging enemy champions with basic attacks or abilities sends Aery to them, dealing 10 - 50 based on level (+0.05 AP) (+0.1 bonus AD).

Empowering or protecting allies with abilities sends Aery to them, shielding them for 30 - 100 based on level (+0.05 AP) (+0.1 bonus AD).

Aery cannot be sent out again until she returns to you.

Manaflow BandManaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.

Cooldown: 15 seconds

TranscendenceTranscendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.

ScorchScorch

Your next damaging ability hit sets champions on fire dealing 20 - 40 bonus magic damage based on level after 1s.

Cooldown: 10s

Biscuit DeliveryBiscuit Delivery

Biscuit Delivery: Gain a Total Biscuit of Everlasting Will every 2 mins, until 6 min.

Biscuits restore 20 + 2% of your maximum health, increased by up to 100% based on missing Health. Consuming or selling a Biscuit permanently increases your max health by 30.

Cosmic InsightCosmic Insight

+18 Summoner Spell Haste
+10 Item Haste

These champions share at least 4 runes with Annie's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Annie's playstyle or want to learn champions with familiar rune setups.Malzahar, Nami, Evelynn, Anivia, Taliyah and 2 others

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Annie Runes - Frequently Asked Questions

What are the best Annie runes in patch 26.5?

The best Annie runes in patch 26.5 use the Domination tree with Electrocute, Cheap Shot, Sixth Sense, and Relentless Hunter, and the Sorcery tree with Absolute Focus and Axiom Arcanist. This rune setup achieves a 68.8% win rate with a 1.2% pick rate.

What is the win rate for Annie's best rune page?

Annie's best rune page has a 68.8% win rate in patch 26.5, which is +18.6% compared to Annie's average win rate. This rune setup has a 1.2% pick rate among Annie players.

What keystone should I use on Annie?

Electrocute from the Domination tree is the best keystone rune for Annie in patch 26.5. This keystone synergizes well with Annie's kit and provides a 68.8% win rate.

What is Annie's primary rune tree?

Annie's primary rune tree is Domination. The optimal Domination runes for Annie are Electrocute, Cheap Shot, Sixth Sense, and Relentless Hunter, with Electrocute being the keystone of choice.

What is Annie's secondary rune tree?

Annie's best secondary rune tree is Sorcery. The recommended Sorcery runes are Absolute Focus and Axiom Arcanist, which complement Annie's Domination primary tree.

What are alternative rune setups for Annie?

An alternative Annie rune setup uses Summon Aery from the Sorcery tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Annie's runes?

Annie's top rune page has a 1.2% pick rate in patch 26.5. This indicates that 1.2% of Annie players use the Electrocute setup with Domination and Sorcery trees.