Karthus - League of Legends Champion
Win Rate
50.1%
Pick Rate
1.2%

Karthusvs Ryze

BMage
Patch26.10
Matches1,492,117
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 20, 2026
MethodologyData Methodology

Karthus vs Ryze is a decisive matchup in LoL patch 26.10. Ryze wins with a 60.0% win rate (+20.0%) over Karthus based on 5 games. Ryze wins the early laning phase while Karthus scales better into the late game. Below you'll find the best Karthus build, runes, laning stats, and strategies for the Karthus vs Ryze matchup.

Karthus Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Karthus performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Ryze - 40.0% win rateRyze(40.0%)
Karthus - 40.0% win rate in this matchup
Karthus
40.0% WR
VS
Ryze vs Karthus matchup - 60.0% win rate
Ryze
60.0% WR

Who Wins the Karthus vs Ryze Matchup?

Ryze wins the Karthus vs Ryze matchup
Winner
Ryze
Matches: 5
40.0%
Win Rate
60.0%
7.0
CS / min
7.5
1,053
DMG / min
827
13,515
Gold / game
14,015
89
Heal / min
216
403
DMG Mitigated / min
534
0.5
CC / min
0.7
0.0%
Early Game WR
100.0%
50.0%
Late Game WR
50.0%

Karthus vs Ryze Matchup Summary

The Karthus vs Ryze matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Ryze wins with a 60.0% win rate compared to Karthus's 40.0%, giving Ryze a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Ryze controls the early laning stage, but Karthus outscales as the game goes longer. The matchup shifts dramatically depending on game length — Ryze needs to press advantages before Karthus reaches their power spikes, while Karthus should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Ryze leads by 259 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Ryze has a strong advantage in this matchup. Karthus players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Ryze overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Karthus vs Ryze Laning Phase Breakdown

Ryze wins the laning phase against Karthus in League of Legends

Ryze is favored during the laning phase against Karthus, winning 4 out of 5 key stat categories. Ryze holds advantages in farming, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
7.0Karthus
7.5Ryze
Ryze edges out Karthus by 0.5 CS per minute — a moderate farming advantage that adds up to roughly 7 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Ryze.
Damage
1,053Karthus
827Ryze
Karthus heavily out-damages Ryze by 226 DMG/min, dominating both short trades and all-in fights. Ryze should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Karthus's sustained damage advantage take over.
Economy
13,515Karthus
14,015Ryze
Ryze earns 500 more gold per game than Karthus, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Ryze slightly faster item completions.
Utility
0.5Karthus
0.7Ryze
Both Karthus and Ryze provide similar amounts of crowd control (0.2s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
492Karthus
750Ryze
Ryze vastly out-sustains Karthus, healing and mitigating 259 more damage per minute. This massive durability gap means Ryze can absorb significant punishment and remain in lane while Karthus is forced to recall. Building grievous wounds early is essential for Karthus, and focusing on burst trade patterns rather than sustained fights is critical.

Best Karthus Build Against Ryze

Spellslinger's Shoes is the optimal boots choice against Ryze, providing the mobility and stats Karthus needs most in this matchup. The top-performing core items for Karthus against Ryze are Shadowflame, Zhonya's Hourglass and Blackfire Torch. This combination gives Karthus an effective balance of damage, survivability, and utility for the matchup. This build performs exceptionally well, achieving a 100.0% win rate across 1 games — well above average and making it the top item path against Ryze. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Karthus vs Ryze matchup.

Early Game vs Late Game

Early Game
Ryze
100.0%
+100.0% advantage
Karthus early game win rateKarthus0.0%
Ryze early game win rateRyze100.0%
Late Game
Karthus
50.0%
+0.0% advantage
Karthus late game win rateKarthus50.0%
Ryze late game win rateRyze50.0%

Ryze dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Karthus. This lopsided early game means Ryze can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Late game (25+ minutes) is equally balanced, with Karthus at 50.0% win rate — only 0.0 points ahead of Ryze. Team fight execution and macro play determine the winner at this stage, not champion matchup advantage.

The power dynamics shift as the game progresses — Ryze has the edge early, but Karthus gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Karthus Runes Against Ryze

Sorcery rune tree - Karthus primary runes vs RyzeSorcery
Deathfire Touch - best Karthus rune vs RyzeAxiom Arcanist - best Karthus rune vs RyzeTranscendence - best Karthus rune vs RyzeScorch - best Karthus rune vs Ryze
Precision rune tree - Karthus secondary runes vs RyzePrecision
Presence of Mind - best Karthus rune vs RyzeCoup de Grace - best Karthus rune vs Ryze
100.0% WR

The Sorcery and Precision rune setup gives Karthus the best tools to compete against Ryze in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Karthus matchup data for League of Legends patch 26.10. The table below shows Karthus's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Karthus build, runes, laning stats, and early vs late game analysis for that specific matchup.

Karthus matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.72%876.51,43615,47744.4%55.0%
38.81%671.31,12513,16139.4%38.2%
56.25%641.31,19413,04853.6%58.3%
47.54%616.51,31513,77460.9%39.5%
49.12%571.31,22613,24150.0%48.1%
48.21%566.41,33314,54271.4%34.3%
49.06%531.61,25814,67943.8%51.4%
55.77%521.41,24614,31768.2%46.7%
45.83%486.41,31013,50359.1%34.6%
51.06%471.61,19014,27650.0%51.7%
47.83%466.61,29814,16350.0%46.4%
64.44%451.51,10713,99162.5%65.5%
38.64%446.81,26513,47840.0%37.5%
47.62%421.41,05612,78643.5%52.6%
47.62%421.21,14712,99544.4%50.0%
51.22%416.41,47315,65130.0%58.1%
45.00%401.41,09414,12441.7%46.4%
72.73%331.31,17112,66290.0%46.1%
60.61%331.61,25315,41075.0%56.0%
57.58%336.51,46816,29470.0%52.2%
46.88%326.31,18014,08654.5%42.9%
46.88%321.51,17813,60046.1%47.4%
51.61%311.51,20214,79846.1%55.6%
41.94%311.61,28414,23630.8%50.0%
58.62%292.01,18514,59654.5%61.1%
37.93%294.91,28913,75540.0%36.8%
51.85%271.21,17213,62150.0%53.3%
33.33%276.31,23015,01728.6%35.0%
51.85%271.51,16813,01436.4%62.5%
60.00%251.41,07412,26860.0%60.0%
56.00%251.21,23414,42140.0%66.7%
33.33%241.21,09511,94633.3%33.3%
43.48%231.81,10011,23244.4%42.9%
39.13%231.41,23813,90250.0%30.8%
50.00%222.01,14814,38725.0%55.6%
59.09%221.51,29414,98042.9%66.7%
40.91%222.11,14013,17857.1%33.3%
47.62%215.31,18714,06150.0%47.4%
57.14%211.51,23914,30633.3%66.7%
70.00%202.51,09412,70890.0%50.0%
36.84%196.01,53514,06266.7%23.1%
26.32%196.21,11210,98511.1%40.0%
52.63%196.71,24912,88355.6%50.0%
47.37%196.71,18112,60988.9%10.0%
63.16%191.51,19914,17375.0%54.5%
78.95%193.11,26815,94160.0%85.7%
33.33%186.21,24313,99557.1%18.2%
50.00%182.21,43716,30575.0%42.9%
41.18%175.01,43416,07250.0%38.5%
58.82%171.31,24914,72871.4%50.0%
58.82%176.01,22814,48733.3%64.3%
64.71%176.31,26112,77671.4%60.0%
52.94%174.31,24414,93866.7%50.0%
47.06%172.194013,06150.0%44.4%
31.25%162.21,22713,87050.0%25.0%
53.33%156.11,30014,18950.0%55.6%
46.67%151.71,36313,81540.0%50.0%
46.67%151.699413,75966.7%33.3%
46.67%153.11,21514,57471.4%25.0%
40.00%151.41,10812,71340.0%40.0%
28.57%143.993710,91225.0%30.0%
42.86%146.51,25415,88325.0%50.0%
42.86%145.81,34513,50460.0%33.3%
21.43%141.41,04411,32212.5%33.3%
50.00%146.91,23014,77125.0%60.0%
35.71%146.71,13512,15022.2%60.0%
61.54%132.81,31812,08950.0%71.4%
76.92%136.71,32415,23850.0%81.8%
66.67%126.01,36315,16666.7%66.7%
58.33%122.392511,28157.1%60.0%
27.27%113.21,33314,15350.0%14.3%
45.45%116.51,13412,11060.0%33.3%
54.55%114.690911,36866.7%40.0%
36.36%113.61,24512,58133.3%37.5%
30.00%103.61,13714,21633.3%28.6%
30.00%104.71,38812,64225.0%33.3%
60.00%106.11,55313,14466.7%50.0%
60.00%101.71,15412,30560.0%60.0%
44.44%91.41,24815,30225.0%60.0%
66.67%95.81,10412,813100.0%57.1%
77.78%96.81,29912,37350.0%85.7%
66.67%91.31,04812,239100.0%40.0%
87.50%84.51,19713,451100.0%80.0%
25.00%83.41,14213,50933.3%20.0%
87.50%86.41,47414,41275.0%100.0%
62.50%87.01,11710,44575.0%50.0%
28.57%74.01,33913,9550.0%40.0%
42.86%71.61,09211,84950.0%33.3%
71.43%76.91,32613,79050.0%100.0%
42.86%76.51,29313,07950.0%33.3%
42.86%75.41,43910,76333.3%50.0%
14.29%72.61,55313,9700.0%20.0%
71.43%76.41,14711,13566.7%100.0%
28.57%73.11,17012,82120.0%50.0%
28.57%76.51,42014,40550.0%20.0%
50.00%65.11,11810,97925.0%100.0%
83.33%66.41,24814,492100.0%75.0%
50.00%64.98565,88340.0%100.0%
50.00%65.97556,75750.0%50.0%
16.67%62.71,32815,1970.0%20.0%
83.33%61.51,33912,763100.0%66.7%
33.33%61.81,19810,54240.0%0.0%
20.00%52.31,12213,874100.0%0.0%
60.00%52.280511,041100.0%50.0%
80.00%56.91,83313,03550.0%100.0%
60.00%56.41,52016,893100.0%50.0%
40.00%57.01,05313,5150.0%50.0%
60.00%54.71,49115,869100.0%50.0%
80.00%57.01,31014,701100.0%75.0%
60.00%56.61,02913,18933.3%100.0%
40.00%57.21,22312,39825.0%100.0%
20.00%56.71,2529,7390.0%33.3%
20.00%56.81,04914,3630.0%20.0%

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Karthus vs Ryze - Frequently Asked Questions

How does Karthus do against Ryze in League of Legends?

Ryze wins the Karthus vs Ryze matchup with a 60.0% win rate compared to Karthus's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Karthus do against Ryze in the early game?

In the early game, Ryze has the advantage against Karthus with a 100.0% win rate versus 0.0%. Ryze players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Karthus do against Ryze in the late game?

In the late game, Karthus takes over the Karthus vs Ryze matchup with a 50.0% win rate compared to 50.0%. Karthus scales better into team fights and objective contests after 25 minutes.

Who wins the Karthus vs Ryze matchup?

Ryze wins the matchup against Karthus with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Ryze is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Karthus build against Ryze?

The best Karthus build against Ryze includes Shadowflame, Zhonya's Hourglass, Blackfire Torch with Spellslinger's Shoes. This build achieves a 100.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Karthus runes against Ryze?

The best Karthus runes against Ryze use the Sorcery primary tree with Precision secondary. This rune setup achieves a 100.0% win rate in the Karthus vs Ryze matchup. See the full rune breakdown in the matchup comparison above.

Does Karthus counter Ryze?

No, Karthus struggles against Ryze with only a 40.0% win rate. Ryze has the advantage in this matchup. Karthus players should focus on safe farming and avoiding extended trades to minimize Ryze's lead.

How do I play Karthus against Ryze?

When playing Karthus against Ryze, play cautiously and avoid Ryze's power spikes. Focus on safe farming — you outscale Ryze in the late game. Use the matchup-specific build and runes above to optimize your chances.