Seraphine - League of Legends Champion
Win Rate
52.1%
Pick Rate
7.6%

Seraphinevs Galio

SSupportMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Seraphine vs Galio is a moderate matchup in LoL patch 26.11. Galio wins with a 51.7% win rate (+3.3%) over Seraphine based on 60 games. Galio holds the advantage in both the early and late game. Below you'll find the best Seraphine build, runes, laning stats, and strategies for the Seraphine vs Galio matchup.

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Seraphine Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Seraphine performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Seraphine - 48.3% win rate in this matchup
Seraphine
48.3% WR
VS
Galio vs Seraphine matchup - 51.7% win rate
Galio
51.7% WR

Who Wins the Seraphine vs Galio Matchup?

Galio wins the Seraphine vs Galio matchup
Winner
Galio
Matches: 60
48.3%
Win Rate
51.7%
2.1
CS / min
2.2
440
DMG / min
463
8,595
Gold / game
8,875
218
Heal / min
107
327
DMG Mitigated / min
1,354
1.2
CC / min
1.3
48.3%
Early Game WR
51.7%
48.4%
Late Game WR
51.6%

Seraphine vs Galio Matchup Summary

The Seraphine vs Galio matchup is a moderate matchup in League of Legends ranked play. Based on 60 recent matches analyzed, Galio wins with a 51.7% win rate compared to Seraphine's 48.3%, giving Galio a 3.3 percentage point advantage. Galio dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Seraphine players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in sustain, where Galio leads by 917 HP/min — a difference that heavily influences the outcome of trades and skirmishes. While Galio is slightly favored, Seraphine can absolutely win this lane through smart trading patterns and wave management. Focus on playing around your cooldowns, conceding CS only when necessary, and capitalizing on Galio's mistakes. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Seraphine vs Galio Laning Phase Breakdown

Galio wins the laning phase against Seraphine in League of Legends

Galio is favored during the laning phase against Seraphine, winning 5 out of 5 key stat categories. Galio holds advantages in farming, damage, gold income, crowd control and sustain, making them the stronger laner in this matchup.

Farming
2.1Seraphine
2.2Galio
Seraphine and Galio farm at nearly identical rates in this matchup, with only a 0.1 CS/min difference. Neither champion holds a meaningful farming advantage, so lane dominance will come from trading and jungle interaction rather than CS leads.
Damage
440Seraphine
463Galio
Damage output is virtually even between Seraphine and Galio, with only 23 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
8,595Seraphine
8,875Galio
Seraphine and Galio generate nearly equal gold per game, with just a 280 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
1.2Seraphine
1.3Galio
Both Seraphine and Galio provide similar amounts of crowd control (0.1s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
544Seraphine
1,461Galio
Galio vastly out-sustains Seraphine, healing and mitigating 917 more damage per minute. This massive durability gap means Galio can absorb significant punishment and remain in lane while Seraphine is forced to recall. Building grievous wounds early is essential for Seraphine, and focusing on burst trade patterns rather than sustained fights is critical.

Best Seraphine Build Against Galio

Ionian Boots of Lucidity is the optimal boots choice against Galio, providing the mobility and stats Seraphine needs most in this matchup. The top-performing core items for Seraphine against Galio are Echoes of Helia, Moonstone Renewer and Rylai's Crystal Scepter. This combination gives Seraphine an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Seraphine vs Galio matchup.

Early Game vs Late Game

Early Game
Galio
51.7%
+3.4% advantage
Seraphine early game win rateSeraphine48.3%
Galio early game win rateGalio51.7%
Late Game
Galio
51.6%
+3.2% advantage
Seraphine late game win rateSeraphine48.4%
Galio late game win rateGalio51.6%

During the early laning phase (first 15 minutes), Galio has a meaningful 51.7% win rate, outperforming Seraphine by 3.4 percentage points. Galio players should look to press this advantage through aggressive trades, wave priority, and early jungle coordination.

In the late game (25+ minutes), Galio takes over with a 51.6% win rate, leading Seraphine by 3.2 percentage points. Galio scales more effectively into team fights and objective contests.

Galio holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Seraphine players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Seraphine Runes Against Galio

Sorcery rune tree - Seraphine primary runes vs GalioSorcery
Summon Aery - best Seraphine rune vs GalioManaflow Band - best Seraphine rune vs GalioTranscendence - best Seraphine rune vs GalioGathering Storm - best Seraphine rune vs Galio
Resolve rune tree - Seraphine secondary runes vs GalioResolve
Font of Life - best Seraphine rune vs GalioRevitalize - best Seraphine rune vs Galio
50.0% WR

The Sorcery and Resolve rune setup gives Seraphine the best tools to compete against Galio in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Seraphine matchup data for League of Legends patch 26.11. The table below shows Seraphine's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Seraphine build, runes, laning stats, and early vs late game analysis for that specific matchup.

Seraphine matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
47.75%7791.74669,35944.9%49.5%
50.91%5501.44939,17358.0%45.0%
49.45%5481.44879,00751.2%48.0%
50.83%5431.44879,19746.8%53.9%
52.69%5011.54979,35248.8%55.5%
50.21%4781.85269,25551.6%49.0%
48.69%4211.54709,01249.2%48.3%
50.00%3341.44539,01050.4%49.7%
50.91%3301.95249,71553.4%49.2%
51.72%3191.44699,56046.7%55.4%
52.44%3071.44938,93052.7%52.2%
53.17%2841.74839,53147.7%56.6%
52.84%2821.44878,90149.2%55.8%
50.78%2581.54449,24750.5%51.0%
47.97%2461.54669,32744.7%50.4%
54.85%2371.85849,76454.8%54.9%
54.85%2371.44528,96551.9%57.4%
53.07%2281.53918,66358.8%46.8%
54.63%2271.84989,66455.6%54.0%
43.13%2111.35028,90135.6%48.8%
52.22%2031.45229,03758.4%47.4%
43.22%1991.54988,96147.1%40.4%
48.44%1921.44979,41851.2%46.3%
53.45%1741.84629,23249.4%56.7%
49.70%1691.66149,70344.4%52.2%
52.26%1551.44799,11856.9%48.2%
57.53%1461.45699,69067.9%51.1%
54.48%1454.566211,52162.3%50.0%
52.52%1391.44899,05164.1%42.7%
61.29%1241.64819,07567.7%54.8%
50.00%1221.44628,51250.8%49.1%
50.00%1201.45089,23252.8%47.8%
51.30%1151.44638,90542.2%57.1%
59.13%1156.281412,23054.7%62.9%
53.49%861.54809,03567.5%41.3%
54.88%825.867711,89860.0%51.9%
61.25%804.878912,00275.9%52.9%
56.76%746.880712,47863.9%50.0%
53.42%732.05109,99152.0%54.2%
56.16%731.55149,44956.8%55.6%
46.88%641.54679,51052.0%43.6%
43.33%601.65579,12160.7%28.1%
48.33%602.14408,59548.3%48.4%
54.24%596.283112,84042.1%60.0%
54.24%593.359210,05860.9%50.0%
60.34%585.375111,90651.9%67.7%
63.16%572.056710,73279.0%55.3%
44.23%521.75759,42052.0%37.0%
51.06%472.04629,10847.6%53.9%
50.00%402.260810,02652.6%47.6%
56.76%376.389112,39562.5%52.4%
44.44%362.55159,08730.8%52.2%
60.61%334.259811,53455.6%62.5%
51.52%335.366611,60061.5%45.0%
42.42%336.281310,73542.1%42.9%
51.52%336.878711,42658.8%43.8%
65.63%321.64749,16373.3%58.8%
65.63%324.168110,15666.7%64.7%
58.06%311.64859,79966.7%52.6%
56.67%306.673310,93362.5%50.0%
41.38%291.45019,36630.8%50.0%
44.44%275.167710,72263.6%31.3%
62.96%271.649810,32862.5%63.2%
54.17%244.26249,65645.5%61.5%
50.00%222.45679,74940.0%58.3%
45.45%223.04909,41825.0%57.1%
63.64%222.250811,56760.0%64.7%
40.00%206.580113,55633.3%41.2%
55.00%206.779212,47966.7%45.5%
55.00%202.04629,45857.1%53.9%
45.00%205.871411,07240.0%50.0%
70.00%201.464510,69887.5%58.3%
63.16%191.443410,16060.0%64.3%
61.11%185.67038,05964.3%50.0%
58.82%176.286512,02650.0%63.6%
35.29%171.244610,23775.0%23.1%
75.00%166.791813,62771.4%77.8%
37.50%161.54798,92840.0%36.4%
60.00%156.776112,98866.7%55.6%
40.00%155.359710,54633.3%44.4%
60.00%151.646310,50775.0%54.5%
50.00%143.264710,32850.0%50.0%
50.00%142.65519,74250.0%50.0%
42.86%144.85849,77450.0%37.5%
53.85%136.392112,20066.7%42.9%
30.77%134.16039,87733.3%28.6%
61.54%133.15949,46842.9%83.3%
58.33%126.78259,19670.0%0.0%
50.00%124.36669,42433.3%66.7%
58.33%126.076411,19160.0%57.1%
72.73%116.175811,907100.0%66.7%
27.27%114.55499,3630.0%50.0%
54.55%116.266011,06050.0%60.0%
60.00%105.680311,24250.0%75.0%
80.00%101.44777,16187.5%50.0%
66.67%94.552110,244100.0%62.5%
44.44%91.84238,69366.7%33.3%
37.50%86.293011,95740.0%33.3%
62.50%81.66239,74233.3%80.0%
37.50%81.53958,01025.0%50.0%
37.50%81.34679,59625.0%50.0%
25.00%85.367010,06850.0%16.7%
25.00%83.45779,67325.0%25.0%
62.50%81.457011,7740.0%71.4%
75.00%85.470711,28850.0%83.3%
50.00%81.14638,69050.0%50.0%
50.00%86.298713,25366.7%40.0%
75.00%81.648710,73550.0%83.3%
85.71%71.45378,417100.0%0.0%
42.86%71.949210,03133.3%50.0%
71.43%73.163510,657100.0%60.0%
57.14%73.473912,184100.0%50.0%
100.00%73.15957,466100.0%100.0%
71.43%73.05208,01175.0%66.7%
33.33%67.382210,97625.0%50.0%
100.00%62.35489,903100.0%100.0%
83.33%62.247410,918100.0%80.0%
50.00%61.63829,86350.0%50.0%
100.00%55.957011,5490.0%100.0%
40.00%51.649610,44750.0%33.3%
60.00%51.256510,3000.0%75.0%
40.00%56.06469,77425.0%100.0%
40.00%53.864610,54966.7%0.0%
80.00%51.549910,15550.0%100.0%

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Seraphine vs Galio - Frequently Asked Questions

How does Seraphine do against Galio in League of Legends?

Galio wins the Seraphine vs Galio matchup with a 51.7% win rate compared to Seraphine's 48.3%, a 3.3 percentage point difference. This data is based on 60 recent ranked games in patch 26.11.

How does Seraphine do against Galio in the early game?

In the early game, Galio has the advantage against Seraphine with a 51.7% win rate versus 48.3%. Galio players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Seraphine do against Galio in the late game?

In the late game, Galio takes over the Seraphine vs Galio matchup with a 51.6% win rate compared to 48.4%. Galio scales better into team fights and objective contests after 25 minutes.

Who wins the Seraphine vs Galio matchup?

Galio wins the matchup against Seraphine with a 51.7% win rate in League of Legends patch 26.11. The 3.3 percentage point advantage means Galio is moderately favored in this lane matchup based on 60 games analyzed.

What is the best Seraphine build against Galio?

The best Seraphine build against Galio includes Echoes of Helia, Moonstone Renewer, Rylai's Crystal Scepter with Ionian Boots of Lucidity. Check the matchup breakdown above for the full item path and build order.

What are the best Seraphine runes against Galio?

The best Seraphine runes against Galio use the Sorcery primary tree with Resolve secondary. This rune setup achieves a 50.0% win rate in the Seraphine vs Galio matchup. See the full rune breakdown in the matchup comparison above.

Does Seraphine counter Galio?

No, Seraphine struggles against Galio with only a 48.3% win rate. Galio has the advantage in this matchup. Seraphine players should focus on safe farming and avoiding extended trades to minimize Galio's lead.

How do I play Seraphine against Galio?

When playing Seraphine against Galio, play cautiously and avoid Galio's power spikes. Look for jungle assistance and team-dependent plays since Galio has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.