Vayne - League of Legends Champion
Win Rate
50.4%
Pick Rate
5.3%

Vaynevs Kayle

BMarksmanAssassin
Patch26.7
Matches508,082
LaneAll Lanes
TierAll Tiers
Last UpdatedApr 15, 2026
MethodologyData Methodology

Vayne vs Kayle is a decisive matchup in LoL patch 26.7. Kayle wins with a 55.6% win rate (+11.1%) over Vayne based on 18 games. Kayle holds the advantage in both the early and late game. Below you'll find the best Vayne build, runes, laning stats, and strategies for the Vayne vs Kayle matchup.

Vayne Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Vayne performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Kayle - 44.4% win rateKayle(44.4%)
Vayne - 44.4% win rate in this matchup
Vayne
44.4% WR
VS
Kayle vs Vayne matchup - 55.6% win rate
Kayle
55.6% WR

Who Wins the Vayne vs Kayle Matchup?

Kayle wins the Vayne vs Kayle matchup
Winner
Kayle
Matches: 18
44.4%
Win Rate
55.6%
6.4
CS / min
6.9
837
DMG / min
664
11,795
Gold / game
12,139
237
Heal / min
287
553
DMG Mitigated / min
418
0.3
CC / min
0.3
42.9%
Early Game WR
57.1%
45.5%
Late Game WR
54.5%

Vayne vs Kayle Matchup Summary

The Vayne vs Kayle matchup is a decisive matchup in League of Legends ranked play. Based on 18 recent matches analyzed, Kayle wins with a 55.6% win rate compared to Vayne's 44.4%, giving Kayle a 11.1 percentage point advantage. Kayle dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Vayne players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Vayne leads by 173 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Kayle has a strong advantage in this matchup. Vayne players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Kayle overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Vayne vs Kayle Laning Phase Breakdown

Vayne wins the laning phase against Kayle in League of Legends

Vayne is favored during the laning phase against Kayle, winning 3 out of 5 key stat categories. Vayne holds advantages in damage, crowd control and sustain, making them the stronger laner in this matchup.

Farming
6.4Vayne
6.9Kayle
Kayle edges out Vayne by 0.4 CS per minute — a moderate farming advantage that adds up to roughly 6 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Kayle.
Damage
837Vayne
664Kayle
Vayne heavily out-damages Kayle by 173 DMG/min, dominating both short trades and all-in fights. Kayle should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Vayne's sustained damage advantage take over.
Economy
11,795Vayne
12,139Kayle
Kayle earns 344 more gold per game than Vayne, equivalent to roughly one additional component item. This economic edge comes from a combination of better farming, kill participation, and objective control, giving Kayle slightly faster item completions.
Utility
0.3Vayne
0.3Kayle
Both Vayne and Kayle provide similar amounts of crowd control (0.0s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
790Vayne
705Kayle
Vayne heals and mitigates 85 more damage per minute than Kayle, providing moderate extra durability. This sustain edge allows Vayne to stay in lane longer between recalls and gradually win extended wars of attrition. Consider building early grievous wounds if playing Kayle.

Best Vayne Build Against Kayle

Mercury's Treads is the optimal boots choice against Kayle, providing the mobility and stats Vayne needs most in this matchup. The top-performing core items for Vayne against Kayle are Essence Reaver, Experimental Hexplate and Infinity Edge. This combination gives Vayne an effective balance of damage, survivability, and utility for the matchup. This build achieves a solid 50.0% win rate across 2 games, proving it to be a reliable item path when facing Kayle. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Vayne vs Kayle matchup.

Early Game vs Late Game

Early Game
Kayle
57.1%
+14.3% advantage
Vayne early game win rateVayne42.9%
Kayle early game win rateKayle57.1%
Late Game
Kayle
54.5%
+9.1% advantage
Vayne late game win rateVayne45.5%
Kayle late game win rateKayle54.5%

Kayle dominates the early game (first 15 minutes) with a commanding 57.1% win rate — a 14.3 percentage point lead over Vayne. This lopsided early game means Kayle can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Kayle is far superior in the late game (25+ minutes), boasting a 54.5% win rate — 9.1 points above Vayne. Extended games heavily favor Kayle, whose kit and scaling make them a dominant force in team fights and objective control.

Kayle holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Vayne players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.

Best Vayne Runes Against Kayle

Precision rune tree - Vayne primary runes vs KaylePrecision
Press the Attack - best Vayne rune vs KaylePresence of Mind - best Vayne rune vs KayleLegend: Bloodline - best Vayne rune vs KayleCoup de Grace - best Vayne rune vs Kayle
Resolve rune tree - Vayne secondary runes vs KayleResolve
Bone Plating - best Vayne rune vs KayleOvergrowth - best Vayne rune vs Kayle
100.0% WR

The Precision and Resolve rune setup gives Vayne the best tools to compete against Kayle in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Vayne matchup data for League of Legends patch 26.7. The table below shows Vayne's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Vayne build, runes, laning stats, and early vs late game analysis for that specific matchup.

Vayne matchup win rates and stats in League of Legends patch 26.7
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
49.02%3576.081713,23145.3%52.0%
52.47%3246.289813,59649.3%55.2%
48.09%3146.283212,81944.0%52.7%
49.01%3025.982512,93747.5%50.3%
52.94%2726.083913,07152.8%53.1%
45.37%2276.496014,25446.9%44.2%
50.00%2226.493713,71750.0%50.0%
52.71%2036.585613,74148.9%56.0%
52.32%1516.582813,28755.4%49.4%
58.39%1496.695312,70051.6%63.5%
51.30%1155.881313,71761.5%42.9%
47.71%1096.088213,23938.2%57.4%
55.67%976.488012,62559.6%51.1%
51.55%976.380612,73552.5%50.0%
50.00%945.983213,59546.7%53.1%
36.36%886.279012,98330.0%41.7%
47.44%786.692813,28446.3%48.6%
61.33%756.692412,10266.7%55.6%
55.56%726.185813,24745.2%63.4%
57.35%686.085313,57456.0%58.1%
36.76%686.288112,39436.7%36.8%
52.54%596.383712,51848.5%57.7%
42.37%596.287012,82834.4%51.9%
38.60%575.760511,22540.0%37.0%
37.50%565.560110,77030.4%42.4%
43.40%536.21,04512,46744.4%42.3%
44.00%506.188613,06147.8%40.7%
53.06%496.11,21413,80450.0%55.2%
65.91%446.186913,29266.7%65.4%
56.82%445.692114,04761.1%53.9%
43.18%445.799611,54831.3%50.0%
50.00%406.384813,58435.3%60.9%
55.00%405.989314,58823.1%70.4%
57.50%406.395114,24860.0%56.7%
48.72%396.595213,49157.9%40.0%
57.89%386.01,02912,41355.0%61.1%
42.11%386.192313,74144.4%40.0%
54.05%377.092811,69252.4%56.3%
40.54%375.880412,22541.2%40.0%
40.00%355.71,14111,80838.9%41.2%
55.88%346.585611,12557.9%53.3%
50.00%326.098613,59966.7%43.5%
66.67%306.289612,54050.0%81.3%
56.67%306.298113,89653.9%58.8%
48.28%296.785812,18028.6%66.7%
55.17%296.31,02413,69462.5%46.1%
51.85%275.798412,39145.5%56.3%
61.54%266.185111,71961.5%61.5%
64.00%256.080811,77055.6%68.8%
44.00%256.892712,26342.9%45.5%
33.33%246.483511,60541.7%25.0%
56.52%235.592112,42462.5%53.3%
43.48%236.383712,92160.0%30.8%
40.91%226.678811,10141.7%40.0%
52.38%215.992313,47740.0%63.6%
60.00%205.290914,35220.0%73.3%
47.37%196.91,00811,89263.6%25.0%
50.00%186.273213,04560.0%37.5%
50.00%186.21,05312,78455.6%44.4%
44.44%186.483711,79542.9%45.5%
50.00%185.875412,37328.6%63.6%
76.47%176.91,02114,29680.0%75.0%
29.41%176.982911,89737.5%22.2%
41.18%176.086215,19160.0%33.3%
43.75%166.083811,77362.5%25.0%
56.25%166.690711,52757.1%55.6%
37.50%165.465913,20816.7%50.0%
68.75%166.793713,92583.3%60.0%
53.33%155.968611,41937.5%71.4%
73.33%156.485112,62177.8%66.7%
50.00%145.785111,11416.7%75.0%
42.86%144.364512,05114.3%71.4%
53.85%133.388514,16275.0%44.4%
53.85%135.71,05513,76250.0%55.6%
58.33%125.656210,02757.1%60.0%
25.00%124.586213,08325.0%25.0%
50.00%126.378413,32833.3%66.7%
27.27%116.277113,46233.3%25.0%
63.64%116.387415,82666.7%62.5%
36.36%116.665110,70650.0%20.0%
45.45%115.591912,62950.0%40.0%
72.73%116.474510,85071.4%75.0%
45.45%116.01,06414,50840.0%50.0%
70.00%106.699613,49075.0%66.7%
40.00%106.887613,21633.3%50.0%
55.56%96.393712,28633.3%100.0%
44.44%96.21,07715,702100.0%28.6%
33.33%96.877411,06920.0%50.0%
25.00%85.569310,37825.0%25.0%
50.00%85.99738,78533.3%100.0%
37.50%81.983414,72733.3%40.0%
42.86%75.690112,809100.0%20.0%
0.00%76.655810,7000.0%0.0%
42.86%74.665114,53850.0%40.0%
71.43%76.168213,12675.0%66.7%
57.14%75.588812,31625.0%100.0%
57.14%75.489512,10050.0%66.7%
42.86%74.077311,64333.3%50.0%
57.14%72.51,31315,57625.0%100.0%
33.33%64.65709,10525.0%50.0%
66.67%65.91,08915,49350.0%75.0%
50.00%65.776213,18250.0%50.0%
50.00%61.989114,832100.0%40.0%
16.67%65.384410,4420.0%33.3%
0.00%65.979510,7240.0%0.0%
83.33%66.196311,361100.0%50.0%
50.00%66.380413,574100.0%40.0%
40.00%54.793914,778100.0%0.0%
60.00%51.71,19517,6480.0%75.0%
20.00%51.56919,37833.3%0.0%
60.00%55.31,10015,380100.0%50.0%
20.00%56.891512,5530.0%33.3%
40.00%56.51,02117,6030.0%40.0%

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Vayne vs Kayle - Frequently Asked Questions

How does Vayne do against Kayle in League of Legends?

Kayle wins the Vayne vs Kayle matchup with a 55.6% win rate compared to Vayne's 44.4%, a 11.1 percentage point difference. This data is based on 18 recent ranked games in patch 26.7.

How does Vayne do against Kayle in the early game?

In the early game, Kayle has the advantage against Vayne with a 57.1% win rate versus 42.9%. Kayle players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Vayne do against Kayle in the late game?

In the late game, Kayle takes over the Vayne vs Kayle matchup with a 54.5% win rate compared to 45.5%. Kayle scales better into team fights and objective contests after 25 minutes.

Who wins the Vayne vs Kayle matchup?

Kayle wins the matchup against Vayne with a 55.6% win rate in League of Legends patch 26.7. The 11.1 percentage point advantage means Kayle is significantly favored in this lane matchup based on 18 games analyzed.

What is the best Vayne build against Kayle?

The best Vayne build against Kayle includes Essence Reaver, Experimental Hexplate, Infinity Edge with Mercury's Treads. This build achieves a 50.0% win rate in the matchup. Check the matchup breakdown above for the full item path and build order.

What are the best Vayne runes against Kayle?

The best Vayne runes against Kayle use the Precision primary tree with Resolve secondary. This rune setup achieves a 100.0% win rate in the Vayne vs Kayle matchup. See the full rune breakdown in the matchup comparison above.

Does Vayne counter Kayle?

No, Vayne struggles against Kayle with only a 44.4% win rate. Kayle has the advantage in this matchup. Vayne players should focus on safe farming and avoiding extended trades to minimize Kayle's lead.

How do I play Vayne against Kayle?

When playing Vayne against Kayle, play cautiously and avoid Kayle's power spikes. Look for jungle assistance and team-dependent plays since Kayle has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.