DoubtCurse
At the end of your turn, if this is in your Hand, gain 1 Weak.
Is Doubt good in Slay the Spire 2?
Doubt is a curse Curse curse in Slay the Spire 2. In combat it resolves as: At the end of your turn, if this is in your Hand, gain 1 Weak. It ranks among the strongest cards its class can draft right now, earning a spot at S tier in our Slay the Spire 2 card tier list.
Across 58 recorded runs, decks running it win 45.1% of the time, comfortably clear of the 19.0% average, by 26.1%. It’s a more selective pick, turning up in just 1.5% of decks that could run it. Ironclad players keep it in 1.3% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.1 times in the decks that take it.
It performs best next to Shrug It Off — together they post a +16.7% swing in win rate. It also has strong chemistry with the relic Pendulum, which moves its win rate by +24.4%. At - energy, it’s upgraded in 0.0% of runs and usually joins the deck around floor 28.
That’s 23 wins, 28 deaths, and 7 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Test Subject Boss, which closes out 6.9% of its appearances. Read on for Doubt’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Curse run.
Doubt Win Rate & Pick Rate
Doubt’s 45.1% win rate clears the 19.0% all-deck average by 26.1%, the gap charted below.
Run Outcomes with Doubt
Doubt has 23 wins and 35 losses over 58 tracked runs (39.7% won); abandoned runs count as losses.
- Wins 39.7%
- Losses 60.3%
Best Cards to Pair with Doubt
Ranked by win-rate lift, Doubt performs best alongside Shrug It Off (+16.7%), Black Hole (+15.7%), and Cascade (+12.7%).
Based on small co-occurring samples — treat these as early signals, not final verdicts.
Best Relics for Doubt
Doubt pairs best with the relics Pendulum (+24.4%), Bag of Preparation (+18.0%), and Lantern (+16.1%), ranked by win-rate lift.
Pendulum8 runs
Bag of Preparation14 runs
Lantern19 runs
Game Piece4 runs
Joss Paper4 runs
Mercury Hourglass10 runsBased on small co-occurring samples — treat these as early signals, not final verdicts.
Doubt Card Details
Doubt is a curse curse costing - energy; it’s upgraded in 0.0% of runs and usually picked up by floor 28.
At the end of your turn, if this is in your Hand, gain 1 Weak.
What Ends Runs with Doubt
Doubt’s most common run-enders are Test Subject Boss (6.9%), Doormaker Boss (6.9%), and Decimillipede Elite (5.2%).
- Test Subject Boss6.9% of runs
- Doormaker Boss6.9% of runs
- Decimillipede Elite5.2% of runs
- Infested Prisms Elite3.4% of runs
- Entomancer Elite3.4% of runs
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Doubt – Frequently Asked Questions
Is Doubt good in Slay the Spire 2?
Across 58 tracked runs, Doubt has a 45.1% win rate — +26.1% above the average deck. Win rate reflects how often runs that include the card end in victory.
What does Doubt do in Slay the Spire 2?
Doubt costs - energy. At the end of your turn, if this is in your Hand, gain 1 Weak.
What class is Doubt in Slay the Spire 2?
Doubt is a Curse Curse Curse.
Is Doubt worth upgrading in Slay the Spire 2?
Doubt can be upgraded at a rest site to improve its effect.
What is the best relic for Doubt?
In tracked runs, Doubt has performed best alongside Pendulum, which lifts its win rate by +24.4% over 8 runs together.
See Also
Compare Doubt with the rest of the best Slay the Spire 2 cards, relics, and classes below.