Ghost SeedRelic
Strikes and Defends gain Ethereal.
Is Ghost Seed good in Slay the Spire 2?
In Slay the Spire 2, Ghost Seed is a shop relic you can pick up on your climb. Its effect: Strikes and Defends gain Ethereal. Right now it’s a high-value grab, sitting at B tier — one of the relics most worth taking.
Over 34 tracked runs the win rate of decks holding it sits at 51.9%, 32.9% ahead of the 19.0% all-run baseline. It sees lighter play, carried in only 0.9% of runs. It does its best work in the hands of the Defect, who post a 100.0% win rate with it. Within Defect runs specifically, it’s carried 0.5% of the time.
Its standout card pairing is Dagger Throw, which lifts the relic’s win rate by +48.1% when both are in play. It also works nicely with Ultimate Defend, good for a +48.1% win-rate change. It typically enters the deck near floor 26. As a shop relic, how often it’s offered depends on its rarity tier.
Of the runs that carried it, 14 ended in victory while 13 fell to a defeat. Its most common run-ender is Kaiser Crab Boss, finishing 8.8% of the runs it appears in. See the best cards, class split, and threats below for the full read on whether Ghost Seed is worth grabbing.
Ghost Seed Win Rate & Pick Rate
At a 51.9% win rate, Ghost Seed runs 32.9% ahead of the 19.0% all-run baseline — the bars below put the two side by side.
Run Outcomes with Ghost Seed
Across the 34 runs that carried Ghost Seed, 14 ended in a win and 20 in a loss — a 41.2% win share, counting abandons as losses.
- Wins 41.2%
- Losses 58.8%
Best Cards with Ghost Seed
The cards that gain the most from carrying Ghost Seed are Dagger Throw (+48.1%), Ultimate Defend (+48.1%), and Infernal Blade (+48.1%), each shown with its win-rate swing.
Dagger Throw3 runs
Ultimate Defend5 runs
Infernal Blade3 runs
Acrobatics3 runs
Battle Trance3 runs
Defend3 runsBased on small co-occurring samples — treat these as early signals, not final verdicts.
Ghost Seed Details
Carried in 0.9% of runs, Ghost Seed is a shop relic typically acquired near floor 26.
Strikes and Defends gain Ethereal.
What Ends Runs with Ghost Seed
Runs carrying Ghost Seed end most often against Kaiser Crab Boss (8.8%) and Knowledge Demon Boss (5.9%) — the share of its runs each accounts for is shown.
- Kaiser Crab Boss8.8% of runs
- Knowledge Demon Boss5.9% of runs
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Ghost Seed – Frequently Asked Questions
Is Ghost Seed good in Slay the Spire 2?
Across 34 tracked runs carrying it, Ghost Seed wins 51.9% of the time — +32.9% above the average run. Win rate reflects how often runs with the relic end in victory.
What does Ghost Seed do in Slay the Spire 2?
Strikes and Defends gain Ethereal.
How rare is Ghost Seed in Slay the Spire 2?
Ghost Seed is a Shop relic, picked up in 0.9% of tracked runs.
What is the best card to use with Ghost Seed?
In tracked runs, Ghost Seed has performed best alongside Dagger Throw, which lifts its win rate by +48.1% over 3 runs together.
Which class is Ghost Seed best in?
Ghost Seed has its highest win rate with The Defect (100.0%).
See Also
Keep exploring Slay the Spire 2 tier lists and stats below.