Sere Talon
Win Rate
14.3%
Pick Rate
0.2%
Δ vs Avg
-4.7

Sere TalonRelic

Ancient
RarityAncient
MethodologyData Methodology

Upon pickup, add random Curses and Wishes to your Deck.

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Is Sere Talon good in Slay the Spire 2?

Sere Talon is an ancient relic in Slay the Spire 2. While carried, it does the following: Upon pickup, add random Curses and Wishes to your Deck. It currently underperforms most relics, sitting at F tier in our Slay the Spire 2 relic rankings.

Across 7 recorded runs, decks carrying it win 14.3% of the time, trailing the 18.9% average by 4.7%. It’s a more situational relic, showing up in just 0.2% of runs. The class that gets the most out of it is the Regent, at a 100.0% win rate. Regent players hold onto it in 0.1% of their runs.

It combos especially well with Clumsy, worth a +10.7% win-rate swing together. Another strong card to run with it is Wish, worth 0.0% to its win rate. On average it’s acquired around floor 33 of a run. Its ancient rarity shapes how frequently you’ll run into it.

It has 1 run wins against 6 losses in our tracked data. When runs carrying it end, the most frequent culprit is Knights Elite, which closes out 28.6% of them. Read on for Sere Talon’s complete card, class, and threat breakdown before you decide to pick it up.

Sere Talon Win Rate & Pick Rate

Sere Talon’s 14.3% win rate trails the 18.9% all-run average by 4.7%, the gap charted below.

Win rate14.3%
Average run18.9%
-4.7% vs averagePick rate: 0.2%7 runs (limited)

Run Outcomes with Sere Talon

Sere Talon has 1 wins and 6 losses over 7 tracked runs (14.3% won); abandoned runs count as losses.

  • Wins 14.3%
  • Losses 85.7%

Best Cards with Sere Talon

Ranked by win-rate lift, the best cards to run with Sere Talon are Clumsy (+10.7%), Wish (0.0%), and Ascender's Bane (-14.3%).

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Sere Talon Win Rate by Class

Sere Talon shows up across 5 classes, led by Regent (100.0%), Defect (0.0%), and Silent (0.0%) by win rate.

Sere Talon Details

Sere Talon is an ancient relic carried in 0.2% of runs and usually picked up around floor 33.

Upon pickup, add random Curses and Wishes to your Deck.

RarityAncient
Typical pickup floor33
Pick rate0.2%
Runs tracked7

What Ends Runs with Sere Talon

Sere Talon’s most common run-enders are Knights Elite (28.6%).

  • Knights Elite28.6% of runs
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Sere Talon – Frequently Asked Questions

Is Sere Talon good in Slay the Spire 2?

Across 7 tracked runs carrying it, Sere Talon wins 14.3% of the time — +4.7% below the average run. Win rate reflects how often runs with the relic end in victory.

What does Sere Talon do in Slay the Spire 2?

Upon pickup, add random Curses and Wishes to your Deck.

How rare is Sere Talon in Slay the Spire 2?

Sere Talon is an Ancient relic, picked up in 0.2% of tracked runs.

What is the best card to use with Sere Talon?

In tracked runs, Sere Talon has performed best alongside Clumsy, which lifts its win rate by +10.7% over 4 runs together.

Which class is Sere Talon best in?

Sere Talon has its highest win rate with The Regent (100.0%).

See Also

Compare Sere Talon with the rest of the best Slay the Spire 2 relics, cards, and classes below.