Kassadin - League of Legends Champion
Win Rate
47.1%
Pick Rate
1.0%

KassadinRunes

FAssassinMage
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 7, 2026
MethodologyData Methodology

Best Kassadin runes for LoL Patch 26.11 - First Strike from the Inspiration tree with Domination secondary (57.1% WR, 1.4% pick rate). Kassadin's optimal primary runes are First Strike, Cash Back, Triple Tonic, Cosmic Insight. Secondary tree: Sudden Impact, Ultimate Hunter.

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Kassadin performs best with First Strike as the keystone rune from the Inspiration tree. Kassadin's optimal primary runes are First Strike, Cash Back, Triple Tonic, Cosmic Insight. Kassadin's secondary rune tree is Domination with Sudden Impact, Ultimate Hunter. This rune setup achieves a 57.14% win rate (+10.0% win rate difference) with a 1.4% pick rate across 28 Kassadin games.
57.1%Win Rate
+10.0%WR Diff
1.4%Pick Rate
First StrikeFirst Strike

Attacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 50% (35% for ranged champions) of bonus damage dealt as gold.

Cooldown: 25 - 15s

Cash BackCash Back

Get 7.5% Gold back when you purchase Legendary Items.

Triple TonicTriple Tonic

Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.

Cosmic InsightCosmic Insight

+18 Summoner Spell Haste
+10 Item Haste

Sudden ImpactSudden Impact

Damaging basic attacks and abilities deal a bonus 20 - 80 True Damage based on level to enemy champions after using a dash, leap, blink, teleport, or when leaving stealth for 4s.

Cooldown: 10s

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

This alternative Kassadin rune build uses Electrocute as the keystone from the Domination tree. The primary runes are Electrocute, Sudden Impact, Grisly Mementos, Ultimate Hunter. Kassadin's secondary rune tree is Resolve with Overgrowth, Bone Plating. This setup achieves a 56.25% win rate (+9.1% win rate difference) with a 0.8% pick rate across 16 games.
56.3%Win Rate
+9.1%WR Diff
0.8%Pick Rate
ElectrocuteElectrocute

Hitting a champion with 3 separate attacks or abilities within 3s deals bonus adaptive damage.

Damage: 70 - 240 (+0.1 bonus AD, +0.05 AP) damage.
Cooldown: 20s

'We called them the Thunderlords, for to speak of their lightning was to invite disaster.'

Sudden ImpactSudden Impact

Damaging basic attacks and abilities deal a bonus 20 - 80 True Damage based on level to enemy champions after using a dash, leap, blink, teleport, or when leaving stealth for 4s.

Cooldown: 10s

Grisly MementosGrisly Mementos

Collect 1 memento on champion takedowns, up to 18 total.

Gain 6 Trinket Haste for each collected. In game modes where vision Trinkets do not exist, instead gain 3 Summoner Spell Haste.

Ultimate HunterUltimate Hunter

Your ultimate gains 6 Ability Haste, plus an additional 5 Ability Haste per Bounty Hunter stack. Bounty Hunter stacks are earned the first time you get a takedown on each enemy champion.

OvergrowthOvergrowth

Absorb life essence from monsters or enemy minions that die near you, permanently gaining 3 maximum health for every 8.

When you've absorbed 120 monsters or enemy minions, gain an additional 3.5% maximum health.

Bone PlatingBone Plating

After taking damage from an enemy champion, the next 3 spells or attacks you receive from them deal 30-60 (based on level) less damage.

Duration: 1.5s
Cooldown: 55s

These champions share at least 4 runes with Kassadin's recommended rune builds. use similar keystone and secondary runes, making them good alternatives if you enjoy Kassadin's playstyle or want to learn champions with familiar rune setups.Akali, Rengar, Kha'Zix, Zed, Xerath and 2 others

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Kassadin Runes - Frequently Asked Questions

What are the best Kassadin runes in patch 26.11?

The best Kassadin runes in patch 26.11 use the Inspiration tree with First Strike, Cash Back, Triple Tonic, and Cosmic Insight, and the Domination tree with Sudden Impact and Ultimate Hunter. This rune setup achieves a 57.1% win rate with a 1.4% pick rate.

What is the win rate for Kassadin's best rune page?

Kassadin's best rune page has a 57.1% win rate in patch 26.11, which is +10.0% compared to Kassadin's average win rate. This rune setup has a 1.4% pick rate among Kassadin players.

What keystone should I use on Kassadin?

First Strike from the Inspiration tree is the best keystone rune for Kassadin in patch 26.11. This keystone synergizes well with Kassadin's kit and provides a 57.1% win rate.

What is Kassadin's primary rune tree?

Kassadin's primary rune tree is Inspiration. The optimal Inspiration runes for Kassadin are First Strike, Cash Back, Triple Tonic, and Cosmic Insight, with First Strike being the keystone of choice.

What is Kassadin's secondary rune tree?

Kassadin's best secondary rune tree is Domination. The recommended Domination runes are Sudden Impact and Ultimate Hunter, which complement Kassadin's Inspiration primary tree.

What are alternative rune setups for Kassadin?

An alternative Kassadin rune setup uses Electrocute from the Domination tree. This alternate build may be preferred in certain matchups or playstyles. Check the alternative rune page above for full details including win rate and pick rate.

How popular are Kassadin's runes?

Kassadin's top rune page has a 1.4% pick rate in patch 26.11. This indicates that 1.4% of Kassadin players use the First Strike setup with Inspiration and Domination trees.