Pantheonvs Karthus
Pantheon vs Karthus is a decisive matchup in LoL patch 26.11. Karthus wins with a 70.0% win rate (+40.0%) over Pantheon based on 10 games. Karthus holds the advantage in both the early and late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Karthus matchup.
Pantheon Matchup Breakdown
Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.
Who Wins the Pantheon vs Karthus Matchup?
Pantheon vs Karthus Matchup Summary
The Pantheon vs Karthus matchup is a decisive matchup in League of Legends ranked play. Based on 10 recent matches analyzed, Karthus wins with a 70.0% win rate compared to Pantheon's 30.0%, giving Karthus a 40.0 percentage point advantage. Karthus dominates at every stage — from early laning through late game team fights. This consistent advantage makes it difficult for Pantheon players to find favorable windows, so team-dependent strategies and avoiding solo confrontations are essential. The most significant statistical gap is in damage output, where Karthus leads by 517 DMG/min — a difference that heavily influences the outcome of trades and skirmishes. Karthus has a strong advantage in this matchup. Pantheon players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Karthus overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.
Pantheon vs Karthus Laning Phase Breakdown
Karthus is favored during the laning phase against Pantheon, winning 3 out of 5 key stat categories. Karthus holds advantages in farming, damage and gold income, making them the stronger laner in this matchup.
Best Pantheon Build Against Karthus
Mercury's Treads is the optimal boots choice against Karthus, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Karthus are Eclipse, Sundered Sky and Spear of Shojin. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Karthus matchup.
Early Game vs Late Game
Pantheon0.0%
Karthus100.0%Pantheon37.5%Karthus62.5%Karthus dominates the early game (first 15 minutes) with a commanding 100.0% win rate — a 100.0 percentage point lead over Pantheon. This lopsided early game means Karthus can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.
Karthus is far superior in the late game (25+ minutes), boasting a 62.5% win rate — 25.0 points above Pantheon. Extended games heavily favor Karthus, whose kit and scaling make them a dominant force in team fights and objective control.
Karthus holds the advantage at every stage of the game, making this a consistently favorable matchup from lane through late game team fights. Pantheon players should look for outplays, team-dependent strategies, and picks rather than relying on scaling to win this matchup.
Best Pantheon Runes Against Karthus
Domination
Inspiration
The Domination and Inspiration rune setup gives Pantheon the best tools to compete against Karthus in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.
Pantheon matchup data for League of Legends patch 26.11. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.
Opponent | Win Rate | Matches | CS/min | DMG/min | Gold/game | Early WR | Late WR |
|---|---|---|---|---|---|---|---|
| 51.56% | 192 | 1.6 | 710 | 10,530 | 48.8% | 53.7% | |
| 45.83% | 192 | 2.0 | 646 | 10,050 | 43.3% | 48.0% | |
| 48.13% | 160 | 1.6 | 701 | 10,561 | 46.8% | 49.4% | |
| 46.53% | 144 | 1.6 | 662 | 10,141 | 52.0% | 40.6% | |
| 43.48% | 138 | 1.6 | 709 | 10,541 | 41.2% | 44.8% | |
| 46.15% | 130 | 1.7 | 674 | 10,681 | 40.9% | 48.8% | |
| 43.75% | 128 | 4.4 | 810 | 11,657 | 38.3% | 46.9% | |
| 46.67% | 120 | 1.6 | 725 | 10,327 | 55.1% | 40.9% | |
| 44.92% | 118 | 5.7 | 875 | 11,362 | 46.8% | 43.7% | |
| 42.59% | 108 | 5.4 | 908 | 11,268 | 46.3% | 38.9% | |
| 45.28% | 106 | 1.6 | 668 | 10,085 | 38.8% | 50.9% | |
| 44.76% | 105 | 5.4 | 893 | 10,776 | 46.0% | 43.6% | |
| 54.46% | 101 | 4.7 | 761 | 11,281 | 60.5% | 50.8% | |
| 46.94% | 98 | 5.1 | 824 | 10,670 | 41.5% | 50.9% | |
| 52.58% | 97 | 2.6 | 899 | 11,208 | 36.6% | 64.3% | |
| 59.38% | 96 | 1.6 | 692 | 11,255 | 55.9% | 61.3% | |
| 55.79% | 95 | 5.5 | 994 | 12,385 | 65.1% | 48.1% | |
| 41.49% | 94 | 2.0 | 736 | 10,826 | 41.7% | 41.4% | |
| 48.89% | 90 | 5.2 | 986 | 10,977 | 57.5% | 39.5% | |
| 47.19% | 89 | 2.1 | 672 | 10,559 | 54.0% | 42.3% | |
| 47.13% | 87 | 1.7 | 643 | 9,646 | 52.0% | 40.5% | |
| 44.05% | 84 | 2.1 | 796 | 11,052 | 41.9% | 45.3% | |
| 53.75% | 80 | 5.4 | 959 | 12,142 | 63.6% | 46.8% | |
| 45.00% | 80 | 1.7 | 761 | 13,105 | 67.9% | 32.7% | |
| 57.69% | 78 | 1.6 | 588 | 9,792 | 62.5% | 52.6% | |
| 42.86% | 77 | 1.7 | 673 | 9,861 | 51.4% | 35.7% | |
| 41.56% | 77 | 1.7 | 628 | 9,754 | 40.0% | 42.9% | |
| 43.06% | 72 | 1.6 | 590 | 9,561 | 48.5% | 38.5% | |
| 57.14% | 70 | 4.4 | 949 | 12,449 | 41.7% | 65.2% | |
| 64.29% | 70 | 2.5 | 818 | 12,326 | 63.6% | 64.6% | |
| 46.38% | 69 | 4.8 | 863 | 11,485 | 41.9% | 50.0% | |
| 49.23% | 65 | 5.0 | 946 | 11,785 | 56.0% | 45.0% | |
| 37.50% | 64 | 5.2 | 1,142 | 10,640 | 45.2% | 30.3% | |
| 46.77% | 62 | 4.3 | 831 | 11,015 | 51.7% | 42.4% | |
| 42.62% | 61 | 4.9 | 1,054 | 11,971 | 47.1% | 40.9% | |
| 46.67% | 60 | 3.0 | 840 | 10,918 | 37.9% | 54.8% | |
| 40.68% | 59 | 1.3 | 750 | 11,709 | 44.0% | 38.2% | |
| 40.68% | 59 | 0.9 | 675 | 11,680 | 33.3% | 48.3% | |
| 44.64% | 56 | 1.8 | 695 | 10,417 | 42.3% | 46.7% | |
| 41.82% | 55 | 2.9 | 740 | 11,007 | 30.0% | 56.0% | |
| 45.45% | 55 | 5.2 | 906 | 11,247 | 47.1% | 44.7% | |
| 44.44% | 54 | 1.4 | 729 | 12,036 | 29.2% | 56.7% | |
| 52.83% | 53 | 5.4 | 962 | 10,416 | 65.4% | 40.7% | |
| 45.28% | 53 | 5.0 | 878 | 10,609 | 62.5% | 31.0% | |
| 46.15% | 52 | 6.0 | 928 | 11,564 | 43.5% | 48.3% | |
| 50.00% | 52 | 3.4 | 946 | 12,340 | 44.0% | 55.6% | |
| 47.06% | 51 | 5.1 | 892 | 11,670 | 57.9% | 40.6% | |
| 48.00% | 50 | 1.5 | 747 | 12,059 | 56.5% | 40.7% | |
| 38.00% | 50 | 5.4 | 850 | 10,778 | 37.5% | 38.5% | |
| 56.00% | 50 | 1.6 | 772 | 11,126 | 57.1% | 55.2% | |
| 53.06% | 49 | 3.3 | 885 | 11,442 | 43.5% | 61.5% | |
| 55.10% | 49 | 1.2 | 774 | 13,281 | 56.3% | 54.5% | |
| 48.94% | 47 | 1.5 | 655 | 10,695 | 42.1% | 53.6% | |
| 61.70% | 47 | 5.3 | 984 | 12,494 | 60.0% | 63.0% | |
| 45.65% | 46 | 4.4 | 830 | 11,847 | 41.2% | 48.3% | |
| 43.48% | 46 | 3.3 | 781 | 10,971 | 34.6% | 55.0% | |
| 53.33% | 45 | 2.5 | 714 | 10,465 | 44.4% | 59.3% | |
| 62.22% | 45 | 2.6 | 778 | 10,996 | 60.0% | 63.3% | |
| 60.00% | 45 | 5.9 | 846 | 11,090 | 61.5% | 57.9% | |
| 56.82% | 44 | 4.9 | 907 | 11,929 | 40.0% | 65.5% | |
| 47.73% | 44 | 4.8 | 770 | 11,457 | 56.3% | 42.9% | |
| 47.73% | 44 | 2.3 | 761 | 10,676 | 60.0% | 41.4% | |
| 51.16% | 43 | 4.7 | 933 | 11,628 | 45.5% | 53.1% | |
| 40.48% | 42 | 1.5 | 619 | 9,396 | 52.2% | 26.3% | |
| 45.24% | 42 | 5.5 | 863 | 11,805 | 43.8% | 46.1% | |
| 57.14% | 42 | 1.8 | 777 | 12,607 | 64.3% | 53.6% | |
| 50.00% | 42 | 4.9 | 786 | 11,701 | 56.3% | 46.1% | |
| 41.46% | 41 | 5.2 | 780 | 10,053 | 26.1% | 61.1% | |
| 53.66% | 41 | 5.0 | 816 | 10,313 | 41.2% | 62.5% | |
| 48.78% | 41 | 1.6 | 641 | 10,105 | 45.5% | 52.6% | |
| 47.50% | 40 | 2.0 | 721 | 9,190 | 50.0% | 44.4% | |
| 47.50% | 40 | 1.4 | 679 | 10,078 | 57.1% | 36.8% | |
| 50.00% | 40 | 5.3 | 957 | 11,736 | 50.0% | 50.0% | |
| 47.50% | 40 | 4.0 | 747 | 10,766 | 55.0% | 40.0% | |
| 35.00% | 40 | 4.1 | 845 | 10,930 | 26.7% | 40.0% | |
| 38.46% | 39 | 5.6 | 1,051 | 12,320 | 33.3% | 40.7% | |
| 47.37% | 38 | 5.9 | 833 | 11,832 | 50.0% | 45.8% | |
| 48.65% | 37 | 1.6 | 738 | 10,766 | 63.6% | 42.3% | |
| 40.54% | 37 | 1.5 | 735 | 10,868 | 56.3% | 28.6% | |
| 40.54% | 37 | 1.1 | 685 | 12,590 | 46.1% | 37.5% | |
| 47.22% | 36 | 4.4 | 766 | 11,089 | 44.4% | 50.0% | |
| 44.44% | 36 | 1.5 | 605 | 10,070 | 36.4% | 48.0% | |
| 42.86% | 35 | 4.7 | 842 | 10,891 | 33.3% | 52.9% | |
| 54.29% | 35 | 5.8 | 770 | 11,583 | 75.0% | 36.8% | |
| 45.71% | 35 | 1.0 | 734 | 11,598 | 42.9% | 47.6% | |
| 47.06% | 34 | 5.7 | 897 | 11,323 | 66.7% | 25.0% | |
| 50.00% | 34 | 1.1 | 683 | 12,420 | 50.0% | 50.0% | |
| 48.48% | 33 | 4.6 | 838 | 11,251 | 42.1% | 57.1% | |
| 69.70% | 33 | 5.2 | 947 | 12,225 | 84.6% | 60.0% | |
| 48.48% | 33 | 2.8 | 742 | 10,938 | 55.6% | 40.0% | |
| 42.42% | 33 | 3.4 | 878 | 11,817 | 60.0% | 34.8% | |
| 46.88% | 32 | 5.5 | 928 | 12,389 | 27.3% | 57.1% | |
| 41.94% | 31 | 5.5 | 983 | 11,071 | 41.2% | 42.9% | |
| 58.06% | 31 | 5.5 | 865 | 10,834 | 38.5% | 72.2% | |
| 35.48% | 31 | 5.1 | 903 | 11,909 | 46.7% | 25.0% | |
| 53.57% | 28 | 1.8 | 704 | 11,459 | 66.7% | 43.8% | |
| 60.71% | 28 | 5.2 | 945 | 12,262 | 58.3% | 62.5% | |
| 42.86% | 28 | 1.8 | 746 | 12,809 | 80.0% | 34.8% | |
| 42.86% | 28 | 1.1 | 765 | 12,724 | 33.3% | 50.0% | |
| 48.15% | 27 | 1.9 | 730 | 11,595 | 41.7% | 53.3% | |
| 33.33% | 27 | 1.6 | 722 | 10,454 | 42.9% | 23.1% | |
| 48.15% | 27 | 4.8 | 769 | 12,224 | 37.5% | 52.6% | |
| 62.96% | 27 | 5.1 | 783 | 10,921 | 64.3% | 61.5% | |
| 57.69% | 26 | 3.8 | 812 | 12,621 | 58.3% | 57.1% | |
| 40.00% | 25 | 0.8 | 609 | 10,484 | 36.4% | 42.9% | |
| 43.48% | 23 | 5.3 | 624 | 10,480 | 42.9% | 44.4% | |
| 43.48% | 23 | 5.9 | 848 | 11,777 | 54.5% | 33.3% | |
| 52.17% | 23 | 0.8 | 735 | 12,470 | 72.7% | 33.3% | |
| 50.00% | 22 | 3.3 | 864 | 11,397 | 61.5% | 33.3% | |
| 68.18% | 22 | 4.9 | 899 | 11,232 | 77.8% | 61.5% | |
| 52.38% | 21 | 4.7 | 848 | 12,486 | 75.0% | 38.5% | |
| 57.14% | 21 | 4.6 | 785 | 11,272 | 57.1% | 57.1% | |
| 38.10% | 21 | 1.5 | 756 | 12,252 | 30.8% | 50.0% | |
| 35.00% | 20 | 1.5 | 690 | 11,140 | 42.9% | 30.8% | |
| 38.89% | 18 | 1.6 | 713 | 12,757 | 28.6% | 45.5% | |
| 44.44% | 18 | 5.2 | 937 | 11,867 | 14.3% | 63.6% | |
| 38.89% | 18 | 5.8 | 978 | 10,604 | 27.3% | 57.1% | |
| 52.94% | 17 | 5.6 | 820 | 12,341 | 62.5% | 44.4% | |
| 56.25% | 16 | 2.8 | 704 | 8,920 | 70.0% | 33.3% | |
| 50.00% | 16 | 0.9 | 721 | 12,873 | 60.0% | 45.5% | |
| 40.00% | 15 | 5.6 | 1,181 | 14,586 | 66.7% | 33.3% | |
| 71.43% | 14 | 4.7 | 939 | 12,752 | 66.7% | 75.0% | |
| 50.00% | 14 | 5.3 | 966 | 13,756 | 50.0% | 50.0% | |
| 50.00% | 14 | 2.1 | 821 | 14,112 | 100.0% | 36.4% | |
| 42.86% | 14 | 1.3 | 847 | 12,311 | 42.9% | 42.9% | |
| 78.57% | 14 | 2.2 | 617 | 8,534 | 75.0% | 83.3% | |
| 57.14% | 14 | 4.8 | 1,102 | 14,742 | 50.0% | 60.0% | |
| 46.15% | 13 | 5.1 | 759 | 12,591 | 33.3% | 50.0% | |
| 53.85% | 13 | 0.9 | 731 | 10,124 | 37.5% | 80.0% | |
| 38.46% | 13 | 1.8 | 733 | 13,195 | 25.0% | 44.4% | |
| 41.67% | 12 | 4.4 | 883 | 11,808 | 50.0% | 33.3% | |
| 33.33% | 12 | 2.5 | 891 | 11,308 | 44.4% | 0.0% | |
| 50.00% | 12 | 4.7 | 717 | 10,830 | 33.3% | 66.7% | |
| 58.33% | 12 | 1.8 | 837 | 13,511 | 66.7% | 55.6% | |
| 18.18% | 11 | 2.8 | 763 | 12,241 | 33.3% | 12.5% | |
| 36.36% | 11 | 1.9 | 902 | 14,286 | 0.0% | 44.4% | |
| 54.55% | 11 | 0.7 | 678 | 13,622 | 50.0% | 55.6% | |
| 54.55% | 11 | 4.3 | 906 | 12,422 | 75.0% | 42.9% | |
| 54.55% | 11 | 5.0 | 748 | 12,461 | 50.0% | 55.6% | |
| 40.00% | 10 | 4.9 | 713 | 9,624 | 20.0% | 60.0% | |
| 30.00% | 10 | 2.6 | 627 | 12,924 | 0.0% | 37.5% | |
| 30.00% | 10 | 1.2 | 858 | 14,529 | 50.0% | 16.7% | |
| 44.44% | 9 | 4.4 | 965 | 12,230 | 0.0% | 57.1% | |
| 33.33% | 9 | 3.6 | 899 | 9,993 | 0.0% | 75.0% | |
| 44.44% | 9 | 4.3 | 864 | 10,460 | 50.0% | 40.0% | |
| 62.50% | 8 | 5.5 | 906 | 12,595 | 33.3% | 80.0% | |
| 37.50% | 8 | 0.9 | 792 | 10,925 | 50.0% | 25.0% | |
| 25.00% | 8 | 3.6 | 735 | 12,617 | 25.0% | 25.0% | |
| 50.00% | 8 | 4.7 | 922 | 12,728 | 33.3% | 60.0% | |
| 57.14% | 7 | 1.0 | 857 | 12,482 | 66.7% | 50.0% | |
| 85.71% | 7 | 4.3 | 755 | 11,853 | 100.0% | 80.0% | |
| 50.00% | 6 | 2.6 | 798 | 10,234 | 50.0% | 50.0% | |
| 50.00% | 6 | 2.0 | 939 | 12,131 | 50.0% | 50.0% | |
| 33.33% | 6 | 4.6 | 835 | 11,134 | 0.0% | 50.0% | |
| 80.00% | 5 | 3.6 | 1,187 | 15,637 | 100.0% | 75.0% | |
| 40.00% | 5 | 4.8 | 699 | 10,818 | 0.0% | 66.7% | |
| 40.00% | 5 | 1.0 | 779 | 11,623 | 33.3% | 50.0% | |
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Pantheon vs Karthus - Frequently Asked Questions
How does Pantheon do against Karthus in League of Legends?
Karthus wins the Pantheon vs Karthus matchup with a 70.0% win rate compared to Pantheon's 30.0%, a 40.0 percentage point difference. This data is based on 10 recent ranked games in patch 26.11.
How does Pantheon do against Karthus in the early game?
In the early game, Karthus has the advantage against Pantheon with a 100.0% win rate versus 0.0%. Karthus players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.
How does Pantheon do against Karthus in the late game?
In the late game, Karthus takes over the Pantheon vs Karthus matchup with a 62.5% win rate compared to 37.5%. Karthus scales better into team fights and objective contests after 25 minutes.
Who wins the Pantheon vs Karthus matchup?
Karthus wins the matchup against Pantheon with a 70.0% win rate in League of Legends patch 26.11. The 40.0 percentage point advantage means Karthus is significantly favored in this lane matchup based on 10 games analyzed.
What is the best Pantheon build against Karthus?
The best Pantheon build against Karthus includes Eclipse, Sundered Sky, Spear of Shojin with Mercury's Treads. Check the matchup breakdown above for the full item path and build order.
What are the best Pantheon runes against Karthus?
The best Pantheon runes against Karthus use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Karthus matchup. See the full rune breakdown in the matchup comparison above.
Does Pantheon counter Karthus?
No, Pantheon struggles against Karthus with only a 30.0% win rate. Karthus has the advantage in this matchup. Pantheon players should focus on safe farming and avoiding extended trades to minimize Karthus's lead.
How do I play Pantheon against Karthus?
When playing Pantheon against Karthus, play cautiously and avoid Karthus's power spikes. Look for jungle assistance and team-dependent plays since Karthus has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.