Pantheon - League of Legends Champion
Win Rate
48.5%
Pick Rate
4.6%

Pantheonvs Vex

FFighterAssassin
Patch26.11
Matches776,441
LaneAll Lanes
TierAll Tiers
Last UpdatedJun 4, 2026
MethodologyData Methodology

Pantheon vs Vex is a decisive matchup in LoL patch 26.11. Vex wins with a 58.3% win rate (+16.7%) over Pantheon based on 12 games. Pantheon wins the early laning phase while Vex scales better into the late game. Below you'll find the best Pantheon build, runes, laning stats, and strategies for the Pantheon vs Vex matchup.

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Pantheon Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Pantheon performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Pantheon - 41.7% win rate in this matchup
Pantheon
41.7% WR
VS
Vex vs Pantheon matchup - 58.3% win rate
Vex
58.3% WR

Who Wins the Pantheon vs Vex Matchup?

Vex wins the Pantheon vs Vex matchup
Winner
Vex
Matches: 12
41.7%
Win Rate
58.3%
4.4
CS / min
5.3
883
DMG / min
858
11,808
Gold / game
11,565
156
Heal / min
99
677
DMG Mitigated / min
465
0.9
CC / min
1.2
50.0%
Early Game WR
50.0%
33.3%
Late Game WR
66.7%

Pantheon vs Vex Matchup Summary

The Pantheon vs Vex matchup is a decisive matchup in League of Legends ranked play. Based on 12 recent matches analyzed, Vex wins with a 58.3% win rate compared to Pantheon's 41.7%, giving Vex a 16.7 percentage point advantage. Game phase dynamics play a critical role here: Pantheon controls the early laning stage, but Vex outscales as the game goes longer. The matchup shifts dramatically depending on game length — Pantheon needs to press advantages before Vex reaches their power spikes, while Vex should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in sustain, where Pantheon leads by 269 HP/min — a difference that heavily influences the outcome of trades and skirmishes. Vex has a strong advantage in this matchup. Pantheon players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Vex overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Pantheon vs Vex Laning Phase Breakdown

Pantheon wins the laning phase against Vex in League of Legends

Pantheon is favored during the laning phase against Vex, winning 3 out of 5 key stat categories. Pantheon holds advantages in damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
4.4Pantheon
5.3Vex
Vex significantly out-farms Pantheon by 0.9 CS per minute, accumulating an estimated 13 CS lead by mid game. This substantial farming gap gives Vex a major gold advantage and earlier item completions. Pantheon players should prioritize wave management techniques like freezing near tower and using abilities efficiently to minimize the deficit.
Damage
883Pantheon
858Vex
Damage output is virtually even between Pantheon and Vex, with only 24 DMG/min separating them. Fights in this matchup are decided more by ability timing and positioning than raw damage numbers, making mechanical skill the deciding factor in trades.
Economy
11,808Pantheon
11,565Vex
Pantheon and Vex generate nearly equal gold per game, with just a 243 gold difference. Neither champion has a clear economic advantage, so gold leads will depend on individual play quality, kill participation, and objective contributions.
Utility
0.9Pantheon
1.2Vex
Both Pantheon and Vex provide similar amounts of crowd control (0.3s/min difference), meaning neither has a significant advantage in locking down opponents for ganks or team fights. Lane ganks are equally effective for both sides.
Sustain
833Pantheon
564Vex
Pantheon vastly out-sustains Vex, healing and mitigating 269 more damage per minute. This massive durability gap means Pantheon can absorb significant punishment and remain in lane while Vex is forced to recall. Building grievous wounds early is essential for Vex, and focusing on burst trade patterns rather than sustained fights is critical.

Best Pantheon Build Against Vex

Swiftmarch is the optimal boots choice against Vex, providing the mobility and stats Pantheon needs most in this matchup. The top-performing core items for Pantheon against Vex are Voltaic Cyclosword, Sundered Sky and Youmuu's Ghostblade. This combination gives Pantheon an effective balance of damage, survivability, and utility for the matchup. Adjustments may be needed based on team compositions and game state, but this build provides the strongest foundation for the Pantheon vs Vex matchup.

Early Game vs Late Game

Early Game
Pantheon
50.0%
+0.0% advantage
Pantheon early game win ratePantheon50.0%
Vex early game win rateVex50.0%
Late Game
Vex
66.7%
+33.3% advantage
Pantheon late game win ratePantheon33.3%
Vex late game win rateVex66.7%

The early game (first 15 minutes) is a toss-up between Pantheon and Vex, with Pantheon holding a razor-thin 50.0% win rate edge (+0.0%). Individual skill and jungle proximity will matter more than champion advantage in the early laning phase.

Vex is far superior in the late game (25+ minutes), boasting a 66.7% win rate — 33.3 points above Pantheon. Extended games heavily favor Vex, whose kit and scaling make them a dominant force in team fights and objective control.

The power dynamics shift as the game progresses — Pantheon has the edge early, but Vex gradually takes over. However, the margins are slim enough that either champion can win at any stage with the right plays. Focus on taking advantages when you have them rather than waiting for a specific game phase.

Best Pantheon Runes Against Vex

Domination rune tree - Pantheon primary runes vs VexDomination
Electrocute - best Pantheon rune vs VexSudden Impact - best Pantheon rune vs VexGrisly Mementos - best Pantheon rune vs VexTreasure Hunter - best Pantheon rune vs Vex
Inspiration rune tree - Pantheon secondary runes vs VexInspiration
Biscuit Delivery - best Pantheon rune vs VexCosmic Insight - best Pantheon rune vs Vex
100.0% WR

The Domination and Inspiration rune setup gives Pantheon the best tools to compete against Vex in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Pantheon matchup data for League of Legends patch 26.11. The table below shows Pantheon's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Pantheon build, runes, laning stats, and early vs late game analysis for that specific matchup.

Pantheon matchup win rates and stats in League of Legends patch 26.11
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
51.56%1921.671010,53048.8%53.7%
45.83%1922.064610,05043.3%48.0%
48.13%1601.670110,56146.8%49.4%
46.53%1441.666210,14152.0%40.6%
43.48%1381.670910,54141.2%44.8%
46.15%1301.767410,68140.9%48.8%
43.75%1284.481011,65738.3%46.9%
46.67%1201.672510,32755.1%40.9%
44.92%1185.787511,36246.8%43.7%
42.59%1085.490811,26846.3%38.9%
45.28%1061.666810,08538.8%50.9%
44.76%1055.489310,77646.0%43.6%
54.46%1014.776111,28160.5%50.8%
46.94%985.182410,67041.5%50.9%
52.58%972.689911,20836.6%64.3%
59.38%961.669211,25555.9%61.3%
55.79%955.599412,38565.1%48.1%
41.49%942.073610,82641.7%41.4%
48.89%905.298610,97757.5%39.5%
47.19%892.167210,55954.0%42.3%
47.13%871.76439,64652.0%40.5%
44.05%842.179611,05241.9%45.3%
53.75%805.495912,14263.6%46.8%
45.00%801.776113,10567.9%32.7%
57.69%781.65889,79262.5%52.6%
42.86%771.76739,86151.4%35.7%
41.56%771.76289,75440.0%42.9%
43.06%721.65909,56148.5%38.5%
57.14%704.494912,44941.7%65.2%
64.29%702.581812,32663.6%64.6%
46.38%694.886311,48541.9%50.0%
49.23%655.094611,78556.0%45.0%
37.50%645.21,14210,64045.2%30.3%
46.77%624.383111,01551.7%42.4%
42.62%614.91,05411,97147.1%40.9%
46.67%603.084010,91837.9%54.8%
40.68%591.375011,70944.0%38.2%
40.68%590.967511,68033.3%48.3%
44.64%561.869510,41742.3%46.7%
41.82%552.974011,00730.0%56.0%
45.45%555.290611,24747.1%44.7%
44.44%541.472912,03629.2%56.7%
52.83%535.496210,41665.4%40.7%
45.28%535.087810,60962.5%31.0%
46.15%526.092811,56443.5%48.3%
50.00%523.494612,34044.0%55.6%
47.06%515.189211,67057.9%40.6%
48.00%501.574712,05956.5%40.7%
38.00%505.485010,77837.5%38.5%
56.00%501.677211,12657.1%55.2%
53.06%493.388511,44243.5%61.5%
55.10%491.277413,28156.3%54.5%
48.94%471.565510,69542.1%53.6%
61.70%475.398412,49460.0%63.0%
45.65%464.483011,84741.2%48.3%
43.48%463.378110,97134.6%55.0%
53.33%452.571410,46544.4%59.3%
62.22%452.677810,99660.0%63.3%
60.00%455.984611,09061.5%57.9%
56.82%444.990711,92940.0%65.5%
47.73%444.877011,45756.3%42.9%
47.73%442.376110,67660.0%41.4%
51.16%434.793311,62845.5%53.1%
40.48%421.56199,39652.2%26.3%
45.24%425.586311,80543.8%46.1%
57.14%421.877712,60764.3%53.6%
50.00%424.978611,70156.3%46.1%
41.46%415.278010,05326.1%61.1%
53.66%415.081610,31341.2%62.5%
48.78%411.664110,10545.5%52.6%
47.50%402.07219,19050.0%44.4%
47.50%401.467910,07857.1%36.8%
50.00%405.395711,73650.0%50.0%
47.50%404.074710,76655.0%40.0%
35.00%404.184510,93026.7%40.0%
38.46%395.61,05112,32033.3%40.7%
47.37%385.983311,83250.0%45.8%
48.65%371.673810,76663.6%42.3%
40.54%371.573510,86856.3%28.6%
40.54%371.168512,59046.1%37.5%
47.22%364.476611,08944.4%50.0%
44.44%361.560510,07036.4%48.0%
42.86%354.784210,89133.3%52.9%
54.29%355.877011,58375.0%36.8%
45.71%351.073411,59842.9%47.6%
47.06%345.789711,32366.7%25.0%
50.00%341.168312,42050.0%50.0%
48.48%334.683811,25142.1%57.1%
69.70%335.294712,22584.6%60.0%
48.48%332.874210,93855.6%40.0%
42.42%333.487811,81760.0%34.8%
46.88%325.592812,38927.3%57.1%
41.94%315.598311,07141.2%42.9%
58.06%315.586510,83438.5%72.2%
35.48%315.190311,90946.7%25.0%
53.57%281.870411,45966.7%43.8%
60.71%285.294512,26258.3%62.5%
42.86%281.874612,80980.0%34.8%
42.86%281.176512,72433.3%50.0%
48.15%271.973011,59541.7%53.3%
33.33%271.672210,45442.9%23.1%
48.15%274.876912,22437.5%52.6%
62.96%275.178310,92164.3%61.5%
57.69%263.881212,62158.3%57.1%
40.00%250.860910,48436.4%42.9%
43.48%235.362410,48042.9%44.4%
43.48%235.984811,77754.5%33.3%
52.17%230.873512,47072.7%33.3%
50.00%223.386411,39761.5%33.3%
68.18%224.989911,23277.8%61.5%
52.38%214.784812,48675.0%38.5%
57.14%214.678511,27257.1%57.1%
38.10%211.575612,25230.8%50.0%
35.00%201.569011,14042.9%30.8%
38.89%181.671312,75728.6%45.5%
44.44%185.293711,86714.3%63.6%
38.89%185.897810,60427.3%57.1%
52.94%175.682012,34162.5%44.4%
56.25%162.87048,92070.0%33.3%
50.00%160.972112,87360.0%45.5%
40.00%155.61,18114,58666.7%33.3%
71.43%144.793912,75266.7%75.0%
50.00%145.396613,75650.0%50.0%
50.00%142.182114,112100.0%36.4%
42.86%141.384712,31142.9%42.9%
78.57%142.26178,53475.0%83.3%
57.14%144.81,10214,74250.0%60.0%
46.15%135.175912,59133.3%50.0%
53.85%130.973110,12437.5%80.0%
38.46%131.873313,19525.0%44.4%
41.67%124.488311,80850.0%33.3%
33.33%122.589111,30844.4%0.0%
50.00%124.771710,83033.3%66.7%
58.33%121.883713,51166.7%55.6%
18.18%112.876312,24133.3%12.5%
36.36%111.990214,2860.0%44.4%
54.55%110.767813,62250.0%55.6%
54.55%114.390612,42275.0%42.9%
54.55%115.074812,46150.0%55.6%
40.00%104.97139,62420.0%60.0%
30.00%102.662712,9240.0%37.5%
30.00%101.285814,52950.0%16.7%
44.44%94.496512,2300.0%57.1%
33.33%93.68999,9930.0%75.0%
44.44%94.386410,46050.0%40.0%
62.50%85.590612,59533.3%80.0%
37.50%80.979210,92550.0%25.0%
25.00%83.673512,61725.0%25.0%
50.00%84.792212,72833.3%60.0%
57.14%71.085712,48266.7%50.0%
85.71%74.375511,853100.0%80.0%
50.00%62.679810,23450.0%50.0%
50.00%62.093912,13150.0%50.0%
33.33%64.683511,1340.0%50.0%
80.00%53.61,18715,637100.0%75.0%
40.00%54.869910,8180.0%66.7%
40.00%51.077911,62333.3%50.0%

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Pantheon vs Vex - Frequently Asked Questions

How does Pantheon do against Vex in League of Legends?

Vex wins the Pantheon vs Vex matchup with a 58.3% win rate compared to Pantheon's 41.7%, a 16.7 percentage point difference. This data is based on 12 recent ranked games in patch 26.11.

How does Pantheon do against Vex in the early game?

In the early game, Pantheon has the advantage against Vex with a 50.0% win rate versus 50.0%. Pantheon players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Pantheon do against Vex in the late game?

In the late game, Vex takes over the Pantheon vs Vex matchup with a 66.7% win rate compared to 33.3%. Vex scales better into team fights and objective contests after 25 minutes.

Who wins the Pantheon vs Vex matchup?

Vex wins the matchup against Pantheon with a 58.3% win rate in League of Legends patch 26.11. The 16.7 percentage point advantage means Vex is significantly favored in this lane matchup based on 12 games analyzed.

What is the best Pantheon build against Vex?

The best Pantheon build against Vex includes Voltaic Cyclosword, Sundered Sky, Youmuu's Ghostblade with Swiftmarch. Check the matchup breakdown above for the full item path and build order.

What are the best Pantheon runes against Vex?

The best Pantheon runes against Vex use the Domination primary tree with Inspiration secondary. This rune setup achieves a 100.0% win rate in the Pantheon vs Vex matchup. See the full rune breakdown in the matchup comparison above.

Does Pantheon counter Vex?

No, Pantheon struggles against Vex with only a 41.7% win rate. Vex has the advantage in this matchup. Pantheon players should focus on safe farming and avoiding extended trades to minimize Vex's lead.

How do I play Pantheon against Vex?

When playing Pantheon against Vex, play cautiously and avoid Vex's power spikes. Look for jungle assistance and team-dependent plays since Vex has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.