Enlightenment•Skill

Is Enlightenment good in Slay the Spire 2?

Enlightenment is an event Event skill in Slay the Spire 2. In combat it resolves as: Reduce the cost of ALL cards in your Hand to 1 this turn. It currently underperforms most alternatives, sitting at D tier in our Slay the Spire 2 card rankings.

Across 7 recorded runs, decks running it win 14.3% of the time, comfortably clear of the 12.6% average, by 1.7%. It’s a more selective pick, turning up in just 1.4% of decks that could run it. Necrobinder players keep it in 1.2% of their runs, so it’s a familiar sight in those decks. On average it shows up 1.9 times in the decks that take it.

It performs best next to Ascender's Bane — together they post a -14.3% swing in win rate. It also has strong chemistry with the relic Bag of Preparation, which moves its win rate by +19.0%. At 0 energy, it’s upgraded in 7.7% of runs and usually joins the deck around floor 23.

That’s 1 wins, 6 deaths, and 0 abandoned runs with it in the deck. The encounter that most often ends a run carrying it is Knowledge Demon Boss, which closes out 42.9% of its appearances. Read on for Enlightenment’s complete synergy, class, and threat breakdown to decide whether it earns a slot in your Event run.

Best Cards to Pair with Enlightenment

Ranked by win-rate lift, Enlightenment performs best alongside Ascender's Bane (-14.3%), Defend (-14.3%), and Falling Star (-14.3%).

Ascender's Bane-14.3%4 runsDefend-14.3%3 runsFalling Star-14.3%3 runsGather Light-14.3%3 runsVenerate-14.3%3 runsWrought in War-14.3%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Enlightenment Win Rate by Class

Enlightenment is played across 4 classes, led by Necrobinder (50.0%), Regent (0.0%), and Ironclad (0.0%) by win rate.

The Necrobinder50.0%2 runsThe Regent0.0%3 runsThe Ironclad0.0%1 runsThe Defect0.0%1 runs

Best Relics for Enlightenment

Enlightenment pairs best with the relics Bag of Preparation (+19.0%), Pael's Flesh (+19.0%), and Divine Right (-14.3%), ranked by win-rate lift.

Bag of Preparation+19.0%3 runsPael's Flesh+19.0%3 runsDivine Right-14.3%3 runs

Based on small co-occurring samples — treat these as early signals, not final verdicts.

Enlightenment Card Details

Enlightenment is an event skill costing 0 energy; it’s upgraded in 7.7% of runs and usually picked up by floor 23.

Reduce the cost of ALL cards in your Hand to 1 this turn.

What Ends Runs with Enlightenment

Enlightenment’s most common run-enders are Knowledge Demon Boss (42.9%) and Infested Prisms Elite (28.6%).

• Knowledge Demon Boss42.9% of runs
• Infested Prisms Elite28.6% of runs

See Also

Compare Enlightenment with the rest of the best Slay the Spire 2 cards, relics, and classes below.