First Strike - League of Legends Rune

First StrikeBuilds

Patch26.7
Matches508,082
TierAll Tiers
Last UpdatedApr 12, 2026
MethodologyData Methodology
Attacks or abilities against an enemy champion within 0.25s of entering champion combat grant 10 gold and First Strike for 3 seconds, causing you to deal 7% extra damage against champions, and granting 50% (35% for ranged champions) of bonus damage dealt as gold.

Cooldown: 25 - 15s

Discover the 11 champions that use First Strike in their primary rune builds. The top performing builds include Aurelion Sol (61.61% rune WR, +11.14% diff), Gangplank (67.57% rune WR, +18.09% diff), Kassadin (75.00% rune WR, +23.71% diff). The "Rune WR Diff" column shows how much better or worse the rune build performs compared to the champion's overall win rate - positive values indicate the rune synergizes well with that champion.

Rank
Champion
Top Rune Build
Rune WR
Rune WR Diff
Rune PR
1
First StrikeMagical FootwearTime Warp TonicCosmic InsightAbsolute FocusGathering Storm
61.61%+11.14%4.50%
2
First StrikeCash BackTriple TonicCosmic InsightBone PlatingUnflinching
67.57%+18.09%1.93%
3
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactUltimate Hunter
75.00%+23.71%1.72%
4
First StrikeCash BackTriple TonicCosmic InsightCheap ShotTreasure Hunter
58.06%+9.00%3.88%
5
First StrikeMagical FootwearTriple TonicJack Of All TradesManaflow BandTranscendence
87.50%+37.27%0.74%
6
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactTreasure Hunter
87.50%+40.28%0.69%
7
First StrikeCash BackTriple TonicCosmic InsightManaflow BandTranscendence
64.15%+12.31%1.09%
8
First StrikeCash BackTriple TonicCosmic InsightSudden ImpactTreasure Hunter
63.16%+12.46%1.15%
9
First StrikeMagical FootwearTriple TonicCosmic InsightCut DownPresence of Mind
70.00%+16.32%0.71%
10
First StrikeMagical FootwearBiscuit DeliveryCosmic InsightManaflow BandScorch
53.57%+4.43%3.70%
11
First StrikeMagical FootwearTriple TonicCosmic InsightSudden ImpactRelentless Hunter
56.67%+11.30%3.47%

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First Strike Builds - Frequently Asked Questions

What are the best First Strike builds in Patch 26.7?

The highest win rate First Strike builds are Aurelion Sol (61.61% WR), Gangplank (67.57% WR), Kassadin (75.00% WR). These builds have been tested across 11 champions in ranked play.

How do I build First Strike on my champion?

First Strike is typically used as part of a Inspiration build. The most successful First Strike builds pair it with Cosmic Insight, Triple Tonic, Cash Back. Check the builds table above to find the optimal rune page for your specific champion.

How many champions can use First Strike effectively?

Currently, 11 champions use First Strike in their optimal builds. The rune is most popular among Mage champions (47% of users).Vel'Koz achieves the highest win rate at 53.68%.

What is the average win rate for First Strike builds?

First Strike builds average a 51.52% win rate across all champions. Top performers like Aurelion Sol and Gangplank exceed this with win rates of 61.61% and 67.57% respectively.