
First Strike Builds
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Discover the 10 champions that use First Strike in their primary rune builds. The top performing builds include Miss Fortune (69.57% rune WR, +18.72% diff), Kassadin (68.75% rune WR, +19.37% diff), Jayce (56.10% rune WR, +7.79% diff). The "Rune WR Diff" column shows how much better or worse the rune build performs compared to the champion's overall win rate - positive values indicate the rune synergizes well with that champion.
Rank | Champion | Top Rune Build | Rune WR | Rune WR Diff | Rune PR |
|---|---|---|---|---|---|
| 1 | 69.57% | +18.72% | 0.21% | ||
| 2 | 68.75% | +19.37% | 1.88% | ||
| 3 | 56.10% | +7.79% | 1.26% | ||
| 4 | 70.45% | +19.30% | 1.30% | ||
| 5 | 62.50% | +12.66% | 0.84% | ||
| 6 | 72.41% | +20.46% | 0.50% | ||
| 7 | 68.75% | +19.05% | 0.14% | ||
| 8 | 66.67% | +16.42% | 0.65% | ||
| 9 | 70.97% | +22.20% | 0.53% | ||
| 10 | 58.82% | +8.54% | 1.22% |
First Strike Builds - Frequently Asked Questions
What are the best First Strike builds in Patch 26.1?
The highest win rate First Strike builds are Miss Fortune (69.57% WR), Kassadin (68.75% WR), Jayce (56.10% WR). These builds have been tested across 10 champions in ranked play.
How do I build First Strike on my champion?
First Strike is typically used as part of a Inspiration build. The most successful First Strike builds pair it with Triple Tonic, Cash Back, Cosmic Insight. Check the builds table above to find the optimal rune page for your specific champion.
How many champions can use First Strike effectively?
Currently, 10 champions use First Strike in their optimal builds. The rune is most popular among Mage champions (47% of users). Veigar achieves the highest win rate at 51.96%.
What is the average win rate for First Strike builds?
First Strike builds average a 51.08% win rate across all champions. Top performers like Miss Fortune and Kassadin exceed this with win rates of 69.57% and 68.75% respectively.
Miss Fortune





Kassadin



Jayce
Gangplank

Kennen
Veigar

Lux
Syndra
Zed
Rumble