Lissandra - League of Legends Champion
Win Rate
50.3%
Pick Rate
1.9%

Lissandravs Caitlyn

BMage
Patch26.10
Matches1,361,747
LaneAll Lanes
TierAll Tiers
Last UpdatedMay 19, 2026
MethodologyData Methodology

Lissandra vs Caitlyn is a decisive matchup in LoL patch 26.10. Caitlyn wins with a 60.0% win rate (+20.0%) over Lissandra based on 5 games. Lissandra wins the early laning phase while Caitlyn scales better into the late game. Below you'll find the best Lissandra build, runes, laning stats, and strategies for the Lissandra vs Caitlyn matchup.

Lissandra Matchup Breakdown

Use the dropdown to select an opponent and see a detailed breakdown of how Lissandra performs against them. You'll get head-to-head win rates, laning stats, the best build and runes for the matchup, and early vs late game analysis — all based on real ranked data.

Compare against an opponent
Caitlyn - 40.0% win rateCaitlyn(40.0%)
Lissandra - 40.0% win rate in this matchup
Lissandra
40.0% WR
VS
Caitlyn vs Lissandra matchup - 60.0% win rate
Caitlyn
60.0% WR

Who Wins the Lissandra vs Caitlyn Matchup?

Caitlyn wins the Lissandra vs Caitlyn matchup
Winner
Caitlyn
Matches: 5
40.0%
Win Rate
60.0%
7.0
CS / min
7.3
623
DMG / min
991
9,888
Gold / game
12,598
131
Heal / min
178
413
DMG Mitigated / min
394
1.4
CC / min
0.7
66.7%
Early Game WR
33.3%
0.0%
Late Game WR
100.0%

Lissandra vs Caitlyn Matchup Summary

The Lissandra vs Caitlyn matchup is a decisive matchup in League of Legends ranked play. Based on 5 recent matches analyzed, Caitlyn wins with a 60.0% win rate compared to Lissandra's 40.0%, giving Caitlyn a 20.0 percentage point advantage. Game phase dynamics play a critical role here: Lissandra controls the early laning stage, but Caitlyn outscales as the game goes longer. The matchup shifts dramatically depending on game length — Lissandra needs to press advantages before Caitlyn reaches their power spikes, while Caitlyn should focus on safe farming and hitting key item breakpoints. The most significant statistical gap is in crowd control, where Lissandra leads by 0.7s CC/min — a difference that heavily influences the outcome of trades and skirmishes. Caitlyn has a strong advantage in this matchup. Lissandra players should play defensively, prioritize safe farming under tower, and look for opportunities created by jungle pressure or Caitlyn overextending. Avoid prolonged trades and wait for team fights where positioning and coordination matter more. Understanding these matchup dynamics is essential for champion select decisions and in-game strategy when facing this lane opponent.

Lissandra vs Caitlyn Laning Phase Breakdown

Caitlyn wins the laning phase against Lissandra in League of Legends

Caitlyn is favored during the laning phase against Lissandra, winning 4 out of 5 key stat categories. Caitlyn holds advantages in farming, damage, gold income and sustain, making them the stronger laner in this matchup.

Farming
7.0Lissandra
7.3Caitlyn
Caitlyn edges out Lissandra by 0.3 CS per minute — a moderate farming advantage that adds up to roughly 5 CS over a 15-minute laning phase. This translates to earlier component purchases and slightly faster power spikes for Caitlyn.
Damage
623Lissandra
991Caitlyn
Caitlyn heavily out-damages Lissandra by 369 DMG/min, dominating both short trades and all-in fights. Lissandra should avoid extended combat and instead focus on burst trade patterns — short engages followed by immediate disengagement — to avoid letting Caitlyn's sustained damage advantage take over.
Economy
9,888Lissandra
12,598Caitlyn
Caitlyn generates a commanding 2,710 more gold per game than Lissandra. This substantial economic advantage means Caitlyn consistently reaches key item breakpoints earlier, creating a compounding lead that grows throughout the game. Lissandra should focus on cost-effective item choices and avoid unnecessary deaths to prevent falling further behind.
Utility
1.4Lissandra
0.7Caitlyn
Lissandra provides 0.7 seconds more crowd control per minute than Caitlyn, offering better gank setup potential and slightly more team fight utility. This CC advantage helps Lissandra coordinate with their jungler and control the pace of skirmishes.
Sustain
544Lissandra
572Caitlyn
Lissandra and Caitlyn have comparable sustain profiles, with only 27 HP/min separating their healing and damage mitigation. Neither champion can out-attrition the other in lane, so trades will be decided by burst potential and ability usage rather than sustain.

Early Game vs Late Game

Early Game
Lissandra
66.7%
+33.3% advantage
Lissandra early game win rateLissandra66.7%
Caitlyn early game win rateCaitlyn33.3%
Late Game
Caitlyn
100.0%
+100.0% advantage
Lissandra late game win rateLissandra0.0%
Caitlyn late game win rateCaitlyn100.0%

Lissandra dominates the early game (first 15 minutes) with a commanding 66.7% win rate — a 33.3 percentage point lead over Caitlyn. This lopsided early game means Lissandra can dictate the pace of the lane from level 1, controlling trades, wave state, and river priority.

Caitlyn is far superior in the late game (25+ minutes), boasting a 100.0% win rate — 100.0 points above Lissandra. Extended games heavily favor Caitlyn, whose kit and scaling make them a dominant force in team fights and objective control.

This matchup features a dramatic power shift: Lissandra must aggressively press their early advantage and close out the game before Caitlyn reaches their scaling breakpoints. If Caitlyn survives the laning phase without falling too far behind, the matchup flips in their favor. Dragon and Rift Herald control are pivotal — the team that secures early objectives can snowball or buy time to scale.

Best Lissandra Runes Against Caitlyn

Domination rune tree - Lissandra primary runes vs CaitlynDomination
Electrocute - best Lissandra rune vs CaitlynCheap Shot - best Lissandra rune vs CaitlynGrisly Mementos - best Lissandra rune vs CaitlynUltimate Hunter - best Lissandra rune vs Caitlyn
Sorcery rune tree - Lissandra secondary runes vs CaitlynSorcery
Manaflow Band - best Lissandra rune vs CaitlynTranscendence - best Lissandra rune vs Caitlyn
100.0% WR

The Domination and Sorcery rune setup gives Lissandra the best tools to compete against Caitlyn in this difficult matchup, compensating for the statistical disadvantages with optimal rune synergies.


Lissandra matchup data for League of Legends patch 26.10. The table below shows Lissandra's win rate, gold difference, and performance stats against every champion in the current meta. Click any champion name to see a detailed head-to-head breakdown including the best Lissandra build, runes, laning stats, and early vs late game analysis for that specific matchup.

Lissandra matchup win rates and stats in League of Legends patch 26.10
Opponent
Win Rate
Matches
CS/min
DMG/min
Gold/game
Early WR
Late WR
52.68%2246.778411,54054.0%51.6%
53.44%1896.883712,02463.5%47.0%
53.37%1786.586612,00641.6%62.4%
54.34%1736.880812,02457.6%52.3%
52.26%1556.677411,51656.9%48.9%
56.08%1486.690212,02057.9%55.0%
47.06%1196.685911,76641.7%50.7%
54.87%1136.896212,12164.0%47.6%
47.75%1116.666910,64638.5%55.9%
46.15%1046.075811,25545.6%46.5%
54.26%946.587412,05167.6%45.6%
39.78%936.576311,70543.8%37.7%
48.91%926.782012,10563.9%39.3%
50.00%747.092810,98051.4%48.6%
48.53%686.593912,00046.7%50.0%
50.79%636.679710,63455.9%44.8%
41.94%627.094010,33444.1%39.3%
47.54%616.877010,64248.4%46.7%
53.45%587.088311,62056.0%51.5%
47.37%576.875711,62754.2%42.4%
54.00%506.378011,07257.7%50.0%
44.00%506.878410,88158.3%30.8%
47.83%466.279510,64554.5%41.7%
48.89%456.576511,36430.0%64.0%
51.11%456.675112,10857.1%48.4%
54.55%446.290911,30647.8%61.9%
38.64%446.574311,45846.1%35.5%
60.47%436.885711,21757.9%62.5%
51.22%416.688612,60450.0%51.9%
36.59%416.090112,01353.9%28.6%
32.50%406.693012,39335.7%30.8%
55.00%406.981310,97371.4%36.8%
47.50%406.679310,25161.1%36.4%
41.03%396.987312,10250.0%36.0%
50.00%386.979811,48262.5%40.9%
51.61%316.279410,94450.0%52.6%
58.62%295.782810,76257.1%60.0%
46.43%285.477710,87063.6%35.3%
50.00%286.984211,21760.0%38.5%
50.00%266.891714,35080.0%42.9%
34.62%266.172412,10627.3%40.0%
57.69%266.884111,38069.2%46.1%
50.00%267.283510,68560.0%36.4%
58.33%247.084612,31150.0%64.3%
50.00%247.281811,29564.3%30.0%
65.22%236.981612,30263.6%66.7%
33.33%216.568111,42344.4%25.0%
52.38%217.587312,64866.7%41.7%
55.00%206.996511,40037.5%66.7%
36.84%193.759610,63950.0%33.3%
57.89%196.083012,67880.0%50.0%
68.42%196.689211,77471.4%66.7%
44.44%186.986311,10044.4%44.4%
70.59%176.879311,41357.1%80.0%
43.75%166.280413,11350.0%41.7%
43.75%164.287613,70966.7%38.5%
50.00%166.771011,45855.6%42.9%
76.92%137.087712,26380.0%75.0%
25.00%126.579411,298100.0%10.0%
41.67%126.399311,98142.9%40.0%
45.45%117.191612,86050.0%42.9%
40.00%101.84987,91750.0%25.0%
60.00%106.81,05712,17633.3%71.4%
50.00%102.662611,62250.0%50.0%
30.00%101.64817,48425.0%33.3%
60.00%107.31,08911,46566.7%50.0%
60.00%102.653210,334100.0%50.0%
40.00%105.674110,77450.0%37.5%
70.00%106.187112,73080.0%60.0%
60.00%106.57327,25166.7%50.0%
20.00%107.086411,95416.7%25.0%
33.33%97.393610,16216.7%66.7%
66.67%96.689910,45560.0%75.0%
33.33%97.577010,76250.0%20.0%
11.11%95.672610,7070.0%12.5%
88.89%96.61,07912,852100.0%83.3%
66.67%97.091814,855100.0%57.1%
62.50%87.493611,63675.0%50.0%
75.00%85.589211,008100.0%50.0%
37.50%87.597914,118100.0%16.7%
75.00%84.365311,20066.7%80.0%
75.00%87.191311,49450.0%100.0%
57.14%73.04845,16250.0%100.0%
28.57%72.469811,25450.0%20.0%
28.57%76.893812,08150.0%20.0%
57.14%75.07268,7190.0%100.0%
28.57%77.01,20012,84850.0%20.0%
33.33%61.84528,34966.7%0.0%
50.00%63.87827,56633.3%66.7%
66.67%62.05738,34633.3%100.0%
66.67%67.36289,807100.0%50.0%
66.67%66.179112,18150.0%75.0%
66.67%65.57527,86566.7%0.0%
50.00%66.593011,4250.0%60.0%
33.33%66.278310,96850.0%25.0%
16.67%66.399410,56850.0%0.0%
80.00%56.86467,52875.0%100.0%
0.00%56.675011,4390.0%0.0%
40.00%54.367511,12850.0%33.3%
20.00%52.470211,203100.0%0.0%
60.00%57.184810,75950.0%66.7%
80.00%56.699312,93150.0%100.0%
20.00%51.85648,39950.0%0.0%
80.00%57.095110,62975.0%100.0%
40.00%57.06239,88866.7%0.0%

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Lissandra vs Caitlyn - Frequently Asked Questions

How does Lissandra do against Caitlyn in League of Legends?

Caitlyn wins the Lissandra vs Caitlyn matchup with a 60.0% win rate compared to Lissandra's 40.0%, a 20.0 percentage point difference. This data is based on 5 recent ranked games in patch 26.10.

How does Lissandra do against Caitlyn in the early game?

In the early game, Lissandra has the advantage against Caitlyn with a 66.7% win rate versus 33.3%. Lissandra players should look to press their lane advantage through aggressive trades and wave control during the first 15 minutes.

How does Lissandra do against Caitlyn in the late game?

In the late game, Caitlyn takes over the Lissandra vs Caitlyn matchup with a 100.0% win rate compared to 0.0%. Caitlyn scales better into team fights and objective contests after 25 minutes.

Who wins the Lissandra vs Caitlyn matchup?

Caitlyn wins the matchup against Lissandra with a 60.0% win rate in League of Legends patch 26.10. The 20.0 percentage point advantage means Caitlyn is significantly favored in this lane matchup based on 5 games analyzed.

What is the best Lissandra build against Caitlyn?

The best Lissandra build against Caitlyn includes optimized core items. Check the matchup breakdown above for the full item path and build order.

What are the best Lissandra runes against Caitlyn?

The best Lissandra runes against Caitlyn use the Domination primary tree with Sorcery secondary. This rune setup achieves a 100.0% win rate in the Lissandra vs Caitlyn matchup. See the full rune breakdown in the matchup comparison above.

Does Lissandra counter Caitlyn?

No, Lissandra struggles against Caitlyn with only a 40.0% win rate. Caitlyn has the advantage in this matchup. Lissandra players should focus on safe farming and avoiding extended trades to minimize Caitlyn's lead.

How do I play Lissandra against Caitlyn?

When playing Lissandra against Caitlyn, play cautiously and avoid Caitlyn's power spikes. Look for jungle assistance and team-dependent plays since Caitlyn has the statistical advantage at most stages. Use the matchup-specific build and runes above to optimize your chances.